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Unreviewed, UniProtKB/TrEMBL Q8NHX0 (Q8NHX0_HUMAN)

Last modified January 19, 2010. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Extracellular signal-related kinase 1c EMBL AAK52330.1
OrganismHomo sapiens (Human) EMBL AAK52330.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. Spearmint SPM003527

Sequence similarities

Contains 1 protein kinase domain.

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Sequences

Sequence LengthMass (Da)Tools
Q8NHX0-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: A82027A684BA12E1

FASTA33538,249
        10         20         30         40         50         60 
MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY 

        70         80         90        100        110        120 
DHVRKTRVAI KKISPFEHQT YCQRTLREIQ ILLRFRHENV IGIRDILRAS TLEAMRDVYI 

       130        140        150        160        170        180 
VQDLMETDLY KLLKSQQLSN DHICYFLYQI LRGLKYIHSA NVLHRDLKPS NLLSNTTCDL 

       190        200        210        220        230        240 
KICDFGLARI ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS 

       250        260        270        280        290        300 
NRPIFPGKHY LDQLNHILAL DLLDRMLTFN PNKRITVEEA LAHPYLEQYY DPTDEPVAEE 

       310        320        330 
PFTFAMELDD LPKERLKELI FQETARFQPG VLEAP

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References

[1]"Properties of human ERK1c."
Aebersold D.M., Yung Y., Seger R.
Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY033608 mRNA. Translation: AAK52330.1.
IPIIPI00304111.
UniGeneHs.861

3D structure databases

HSSPHSSP built from PDB template 1PME based on UniProtKB P28482.
SMRQ8NHX0. Positions 19-330.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8NHX0.

Proteomic databases

PRIDEQ8NHX0.

Genome annotation databases

EnsemblENST00000322266; ENSP00000327293; ENSG00000102882; Homo sapiens. [Genome view]
ENST00000395202; ENSP00000378628; ENSG00000102882; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:6877. MAPK3.

Phylogenomic databases

HOVERGENQ8NHX0.
PhylomeDBQ8NHX0.

Gene expression databases

ArrayExpressQ8NHX0.
BgeeQ8NHX0.

Family and domain databases

InterProIPR008349. Erk_1_2_MAPK.
IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR017442. Se/Thr_prot_kinase-like_dom.
IPR002290. Ser/Thr_prot_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSPR01770. ERK1ERK2MAPK.
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ8NHX0_HUMAN
AccessionPrimary (citable) accession number: Q8NHX0
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: January 19, 2010
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information