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Protein

60S acidic ribosomal protein P0-like

Gene

RPLP0P6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P0-like
Gene namesi
Name:RPLP0P6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:36404. RPLP0P6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74723863.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 31731760S acidic ribosomal protein P0-likePRO_0000349111Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei304 – 3041PhosphoserineBy similarity
Modified residuei307 – 3071PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8NHW5.
PaxDbiQ8NHW5.
PRIDEiQ8NHW5.
TopDownProteomicsiQ8NHW5.

PTM databases

iPTMnetiQ8NHW5.
PhosphoSiteiQ8NHW5.
SwissPalmiQ8NHW5.

Expressioni

Organism-specific databases

HPAiHPA003512.

Interactioni

Subunit structurei

P0 forms a pentameric complex by interaction with dimers of P1 and P2.By similarity

Protein-protein interaction databases

IntActiQ8NHW5. 4 interactions.
MINTiMINT-1143683.
STRINGi9606.ENSP00000339027.

Structurei

3D structure databases

ProteinModelPortaliQ8NHW5.
SMRiQ8NHW5. Positions 7-211.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L10P family.Curated

Phylogenomic databases

eggNOGiKOG0815. Eukaryota.
COG0244. LUCA.
HOGENOMiHOG000210987.
HOVERGENiHBG000711.
InParanoidiQ8NHW5.

Family and domain databases

InterProiIPR030670. L10E_eukaryotes.
IPR001790. Ribosomal_L10P.
[Graphical view]
PfamiPF00466. Ribosomal_L10. 1 hit.
[Graphical view]
PIRSFiPIRSF039087. L10E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NHW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK
60 70 80 90 100
VVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIWGNVGFVF TKEDLTEIRD
110 120 130 140 150
MLLANKVPAA ARAGAIAPCE VTVPAQNTGL GPEKTSFFQA LGITTKISRG
160 170 180 190 200
TIEILSDVQL IKTGDKVGAS EATLLNMLNI SPFSFGLVIQ QVFDNGSIYN
210 220 230 240 250
PEVLDKTEET LHSRFLEGVR NVASVCLQTG YPTVASVPHS IINGYKRVLA
260 270 280 290 300
LSVETDYTFP LAENVKAFLA DPSAFVAAAP VAADTTAAPA AAAAPAKVEA
310
KEESEESDED MGFGLFD
Length:317
Mass (Da):34,364
Last modified:October 1, 2002 - v1
Checksum:iCEC317735C03FA16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY064377 Genomic DNA. Translation: AAL62450.1.
CR596098 mRNA. No translation available.
CH471053 Genomic DNA. Translation: EAX00373.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY064377 Genomic DNA. Translation: AAL62450.1.
CR596098 mRNA. No translation available.
CH471053 Genomic DNA. Translation: EAX00373.1.

3D structure databases

ProteinModelPortaliQ8NHW5.
SMRiQ8NHW5. Positions 7-211.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8NHW5. 4 interactions.
MINTiMINT-1143683.
STRINGi9606.ENSP00000339027.

PTM databases

iPTMnetiQ8NHW5.
PhosphoSiteiQ8NHW5.
SwissPalmiQ8NHW5.

Polymorphism and mutation databases

DMDMi74723863.

Proteomic databases

EPDiQ8NHW5.
PaxDbiQ8NHW5.
PRIDEiQ8NHW5.
TopDownProteomicsiQ8NHW5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiRPLP0P6.
H-InvDBHIX0029989.
HIX0161916.
HGNCiHGNC:36404. RPLP0P6.
HPAiHPA003512.
neXtProtiNX_Q8NHW5.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0815. Eukaryota.
COG0244. LUCA.
HOGENOMiHOG000210987.
HOVERGENiHBG000711.
InParanoidiQ8NHW5.

Family and domain databases

InterProiIPR030670. L10E_eukaryotes.
IPR001790. Ribosomal_L10P.
[Graphical view]
PfamiPF00466. Ribosomal_L10. 1 hit.
[Graphical view]
PIRSFiPIRSF039087. L10E. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Physical/genetic map of the 2p22-2p21 region on chromosome 2."
    Gorry M.C., Zhang Y., Marks J.J., Suppe B., Hart P.S., Corteli J.R., Pallos D., Hart T.C.
    Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Full-length cDNA libraries and normalization."
    Li W.B., Gruber C., Jessee J., Polayes D.
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Cervix carcinoma.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiRLA0L_HUMAN
AccessioniPrimary (citable) accession number: Q8NHW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.