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Protein

60S acidic ribosomal protein P0-like

Gene

RPLP0P6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.By similarity

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P0-like
Alternative name(s):
Large ribosomal subunit protein uL10-like
Gene namesi
Name:RPLP0P6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:36404. RPLP0P6.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74723863.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003491111 – 31760S acidic ribosomal protein P0-likeAdd BLAST317

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei24PhosphotyrosineBy similarity1
Modified residuei59PhosphothreonineBy similarity1
Cross-linki297Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Cross-linki297Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei304PhosphoserineBy similarity1
Modified residuei307PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ8NHW5.
MaxQBiQ8NHW5.
PaxDbiQ8NHW5.
PeptideAtlasiQ8NHW5.
PRIDEiQ8NHW5.
TopDownProteomicsiQ8NHW5.

PTM databases

iPTMnetiQ8NHW5.
PhosphoSitePlusiQ8NHW5.
SwissPalmiQ8NHW5.

Expressioni

Organism-specific databases

HPAiHPA003512.

Interactioni

Subunit structurei

P0 forms a pentameric complex by interaction with dimers of P1 and P2.By similarity

Protein-protein interaction databases

IntActiQ8NHW5. 5 interactors.
MINTiMINT-1143683.

Structurei

3D structure databases

ProteinModelPortaliQ8NHW5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0815. Eukaryota.
COG0244. LUCA.
HOGENOMiHOG000210987.
HOVERGENiHBG000711.
InParanoidiQ8NHW5.

Family and domain databases

InterProiView protein in InterPro
IPR030670. L10E_eukaryotes.
IPR001790. Ribosomal_L10P.
PfamiView protein in Pfam
PF00466. Ribosomal_L10. 1 hit.
PIRSFiPIRSF039087. L10E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NHW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK
60 70 80 90 100
VVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIWGNVGFVF TKEDLTEIRD
110 120 130 140 150
MLLANKVPAA ARAGAIAPCE VTVPAQNTGL GPEKTSFFQA LGITTKISRG
160 170 180 190 200
TIEILSDVQL IKTGDKVGAS EATLLNMLNI SPFSFGLVIQ QVFDNGSIYN
210 220 230 240 250
PEVLDKTEET LHSRFLEGVR NVASVCLQTG YPTVASVPHS IINGYKRVLA
260 270 280 290 300
LSVETDYTFP LAENVKAFLA DPSAFVAAAP VAADTTAAPA AAAAPAKVEA
310
KEESEESDED MGFGLFD
Length:317
Mass (Da):34,364
Last modified:October 1, 2002 - v1
Checksum:iCEC317735C03FA16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY064377 Genomic DNA. Translation: AAL62450.1.
CR596098 mRNA. No translation available.
CH471053 Genomic DNA. Translation: EAX00373.1.

Similar proteinsi

Entry informationi

Entry nameiRLA0L_HUMAN
AccessioniPrimary (citable) accession number: Q8NHW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 1, 2002
Last modified: August 30, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families