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Q8NHV7

- Q8NHV7_HUMAN

UniProt

Q8NHV7 - Q8NHV7_HUMAN

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Protein
Submitted name: Interleukin 5 receptor, alpha
Gene
IL5RA
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cytokine receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Interleukin 5 receptor, alphaImported
    Gene namesi
    Name:IL5RAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro
    Complete GO annotation...

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA29834.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8NHV7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NHV7.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000070224.
    HOVERGENiHBG052117.
    KOiK05067.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    InterProiIPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR015321. IL-6_rcpt_alpha-bd.
    IPR003532. Short_hematopoietin_rcpt_2_CS.
    [Graphical view]
    PfamiPF09240. IL6Ra-bind. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 2 hits.
    PROSITEiPS01356. HEMATOPO_REC_S_F2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8NHV7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIIVAHVLLI LLGATEILQA DLLPDEKISL LPPVNFTIKV TGLAQVLLQW    50
    KPNPDQEQRN VNLEYQVKIN APKEDDYETR ITESKCVTIL HKGFSASVRT 100
    ILQNDHSLLA SSWASAELHA PPGSPGTSIV NLTCTTNTTE DNYSRLRSYQ 150
    VSLHCTWLVG TDAPEDTQYF LYYRYGSWTE ECQEYSKDTL GRNIACWFPR 200
    TFILSKGRDW LAVLVDGSSK HSAIRPFDQL FALHAIDQIN PPLNVTAEIE 250
    GTRLSIQWEK PVSAFPIHCF DYEVKIHNTR NGYLQIEKLM TNAFISIIDD 300
    LSKYDVQVRA AVSSMCREAG LWSEWSQPIY VGFSR 335
    Length:335
    Mass (Da):37,985
    Last modified:October 1, 2002 - v1
    Checksum:i4AE70762398E5E11
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC027599 mRNA. Translation: AAH27599.1.
    RefSeqiNP_783855.1. NM_175728.2.
    UniGeneiHs.68876.

    Genome annotation databases

    GeneIDi3568.
    KEGGihsa:3568.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC027599 mRNA. Translation: AAH27599.1 .
    RefSeqi NP_783855.1. NM_175728.2.
    UniGenei Hs.68876.

    3D structure databases

    ProteinModelPortali Q8NHV7.
    ModBasei Search...

    Proteomic databases

    PRIDEi Q8NHV7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3568.
    KEGGi hsa:3568.

    Organism-specific databases

    CTDi 3568.
    PharmGKBi PA29834.

    Phylogenomic databases

    HOGENOMi HOG000070224.
    HOVERGENi HBG052117.
    KOi K05067.

    Miscellaneous databases

    GenomeRNAii 3568.
    NextBioi 13936.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    InterProi IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR015321. IL-6_rcpt_alpha-bd.
    IPR003532. Short_hematopoietin_rcpt_2_CS.
    [Graphical view ]
    Pfami PF09240. IL6Ra-bind. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 2 hits.
    PROSITEi PS01356. HEMATOPO_REC_S_F2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: TestisImported.

    Entry informationi

    Entry nameiQ8NHV7_HUMAN
    AccessioniPrimary (citable) accession number: Q8NHV7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: April 16, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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