Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative olfactory receptor 2W6

Gene

OR2W6P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Enzyme and pathway databases

BioCyciZFISH:ENSG00000168126-MONOMER.
ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative olfactory receptor 2W6
Alternative name(s):
Olfactory receptor OR6-3
Putative olfactory receptor 2W7
Gene namesi
Name:OR2W6P
Synonyms:OR2W7P
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:15072. OR2W6P.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 31ExtracellularSequence analysisAdd BLAST31
Transmembranei32 – 52Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini53 – 63CytoplasmicSequence analysisAdd BLAST11
Transmembranei64 – 84Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini85 – 103ExtracellularSequence analysisAdd BLAST19
Transmembranei104 – 124Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini125 – 145CytoplasmicSequence analysisAdd BLAST21
Transmembranei146 – 166Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini167 – 202ExtracellularSequence analysisAdd BLAST36
Transmembranei203 – 223Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini224 – 245CytoplasmicSequence analysisAdd BLAST22
Transmembranei246 – 266Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini267 – 277ExtracellularSequence analysisAdd BLAST11
Transmembranei278 – 298Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini299 – 318CytoplasmicSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74760337.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003425121 – 318Putative olfactory receptor 2W6Add BLAST318

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi103 ↔ 185PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiQ8NHA6.

Structurei

3D structure databases

ProteinModelPortaliQ8NHA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG017625.
InParanoidiQ8NHA6.
PhylomeDBiQ8NHA6.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NHA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFYHVGQAA FELLTSSFIL VGFSDRPHLE LIVFVVVLIF YLLTLLGNMT
60 70 80 90 100
IVLLSALDSR LHTPMYFFLA NLSFLDMCFT TGSIPQMLYN LWGPDKTISY
110 120 130 140 150
VGCAIQLYFV LALGGVECVL LAVMAYDRYA AVCKPLHYTI IMHPRLCGQL
160 170 180 190 200
ASVAWLSGFG NSLIMAPQTL MLPRCGHRRV DHFLCEMPAL IGMACVDTMM
210 220 230 240 250
LEALAFALAI FIILAPLILI LISYGYVGGT VLRIKSAAGR KKAFNTCSSH
260 270 280 290 300
LIVVSLFYGT IIYMYLQPAN TYSQDQGKFL TLFYTIVTPS VNPLIYTLRN
310
KDVKEAMKKV LGKGSAEI
Length:318
Mass (Da):35,283
Last modified:October 1, 2002 - v1
Checksum:iE70ED182920CF4AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065475 Genomic DNA. Translation: BAC05729.1.
CH471081 Genomic DNA. Translation: EAX03126.1.
BK004697 Genomic DNA. No translation available.

Cross-referencesi

Web resourcesi

Human Olfactory Receptor Data Exploratorium (HORDE)

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065475 Genomic DNA. Translation: BAC05729.1.
CH471081 Genomic DNA. Translation: EAX03126.1.
BK004697 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ8NHA6.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Polymorphism and mutation databases

DMDMi74760337.

Proteomic databases

PRIDEiQ8NHA6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiOR2W6P.
HGNCiHGNC:15072. OR2W6P.
neXtProtiNX_Q8NHA6.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG017625.
InParanoidiQ8NHA6.
PhylomeDBiQ8NHA6.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000168126-MONOMER.
ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOR2W6_HUMAN
AccessioniPrimary (citable) accession number: Q8NHA6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.