Q8NGX4 (Q8NGX4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Seven transmembrane helix receptor EMBL BAC05868.1

Gene names

Name:

OR10K2 HGNC 14826

Organism

Homo sapiens (Human) EMBL BAC05868.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity SAAS SAAS000725.

Ontologies

Keywords
Biological process	Olfaction SAAS SAAS000725 Sensory transduction
Cellular component	Cell membrane SAAS SAAS000725 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000725
Molecular function	G-protein coupled receptor SAAS SAAS000725 Receptor Transducer
Gene Ontology (GO)
Biological_process	detection of chemical stimulus involved in sensory perception of smell Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW olfactory receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8NGX4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 79950D2ED4424A9E	FASTA	261	29,358
	10 20 30 40 50 60 MERVNETVVR EVIFLGFSSL ARLQQLLFVI FLLLYLFTLG TNAIIISTIV LDRALHIPMY 70 80 90 100 110 120 FFLAILSCSE ICYTFIIVPK MLVDLLSQKK TISFLGCAIQ MFSFLFLGCS HSFLLAVMGY 130 140 150 160 170 180 DRYIAICNPL RYSVLMGHGV CMGLVAAACA CGFTVAQIIT SLVFHLPFYS SNQLHHFFCD 190 200 210 220 230 240 IAPVLKLASH HNHFSQIVIF MLCTLVLAIP LLLILVSYVH ILSAILQFPS TLGTQEASIS 250 260 RIFLDVFWTS VFQNHQITIV K

References

[1]

"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes." Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CBRC7TM_205 EMBL BAC05868.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB065642 Genomic DNA. Translation: BAC05868.1.
IPI	IPI00745594.
UniGene	Hs.626815.
3D structure databases
ProteinModelPortal	Q8NGX4.
SMR	Q8NGX4. Positions 109-140.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000041365.
HOVERGEN	HBG017625.
PhylomeDB	Q8NGX4.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8NGX4_HUMAN

Accession

Primary (citable) accession number: Q8NGX4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	May 29, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.