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Protein

Olfactory receptor 13J1

Gene

OR13J1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 13J1
Alternative name(s):
Olfactory receptor OR9-2
Gene namesi
Name:OR13J1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000168828.5
HGNCiHGNC:15108 OR13J1
neXtProtiNX_Q8NGT2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini47 – 54CytoplasmicSequence analysis8
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini76 – 99ExtracellularSequence analysisAdd BLAST24
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini161 – 197ExtracellularSequence analysisAdd BLAST37
Transmembranei198 – 217Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini218 – 237CytoplasmicSequence analysisAdd BLAST20
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 271ExtracellularSequence analysisAdd BLAST13
Transmembranei272 – 292Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini293 – 312CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi392309
PharmGKBiPA32049

Polymorphism and mutation databases

BioMutaiOR13J1
DMDMi38372769

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001507411 – 312Olfactory receptor 13J1Add BLAST312

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation
Glycosylationi191N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8NGT2
PeptideAtlasiQ8NGT2
PRIDEiQ8NGT2

PTM databases

PhosphoSitePlusiQ8NGT2

Expressioni

Gene expression databases

BgeeiENSG00000168828
CleanExiHS_OR13J1

Interactioni

Protein-protein interaction databases

BioGridi134172, 11 interactors
STRINGi9606.ENSP00000367219

Structurei

3D structure databases

ProteinModelPortaliQ8NGT2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJWF Eukaryota
ENOG41113GF LUCA
GeneTreeiENSGT00760000119058
HOGENOMiHOG000041365
HOVERGENiHBG017625
InParanoidiQ8NGT2
KOiK04257
OMAiLCLFKSV
OrthoDBiEOG091G0AZH
PhylomeDBiQ8NGT2
TreeFamiTF352686

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NGT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPLNRTEVS EFFLKGFSGY PALEHLLFPL CSAMYLVTLL GNTAIMAVSV
60 70 80 90 100
LDIHLHTPVY FFLGNLSTLD ICYTPTFVPL MLVHLLSSRK TISFAVCAIQ
110 120 130 140 150
MCLSLSTGST ECLLLAITAY DRYLAICQPL RYHVLMSHRL CVLLMGAAWV
160 170 180 190 200
LCLLKSVTEM VISMRLPFCG HHVVSHFTCK ILAVLKLACG NTSVSEDFLL
210 220 230 240 250
AGSILLLPVP LAFICLSYLL ILATILRVPS AARCCKAFST CLAHLAVVLL
260 270 280 290 300
FYGTIIFMYL KPKSKEAHIS DEVFTVLYAM VTTMLNPTIY SLRNKEVKEA
310
ARKVWGRSRA SR
Length:312
Mass (Da):34,689
Last modified:October 1, 2002 - v1
Checksum:i7AE2FAB223A9218B
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_053304133H → R. Corresponds to variant dbSNP:rs7044405Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065705 Genomic DNA Translation: BAC05928.1
AL133410 Genomic DNA No translation available.
CH471071 Genomic DNA Translation: EAW58323.1
BC136715 mRNA Translation: AAI36716.1
BC136716 mRNA Translation: AAI36717.1
AF399603 Genomic DNA Translation: AAK95088.1
BK004442 Genomic DNA Translation: DAA04840.1
CCDSiCCDS35011.1
RefSeqiNP_001004487.1, NM_001004487.1
UniGeneiHs.527480

Genome annotation databases

EnsembliENST00000377981; ENSP00000367219; ENSG00000168828
GeneIDi392309
KEGGihsa:392309
UCSCiuc011lph.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiO13J1_HUMAN
AccessioniPrimary (citable) accession number: Q8NGT2
Secondary accession number(s): B2RN66, Q6IF20, Q96R40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: February 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. SIMILARITY comments
    Index of protein domains and families

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