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Protein

Olfactory receptor 9I1

Gene

OR9I1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 9I1
Alternative name(s):
Olfactory receptor OR11-228
Gene namesi
Name:OR9I1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000172377.1.
HGNCiHGNC:14718. OR9I1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini47 – 54CytoplasmicSequence analysis8
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini76 – 99ExtracellularSequence analysisAdd BLAST24
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini161 – 197ExtracellularSequence analysisAdd BLAST37
Transmembranei198 – 217Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini218 – 237CytoplasmicSequence analysisAdd BLAST20
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 271ExtracellularSequence analysisAdd BLAST13
Transmembranei272 – 292Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini293 – 314CytoplasmicSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32794.

Polymorphism and mutation databases

BioMutaiOR9I1.
DMDMi38372750.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001506811 – 314Olfactory receptor 9I1Add BLAST314

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

EPDiQ8NGQ6.
PaxDbiQ8NGQ6.
PRIDEiQ8NGQ6.

PTM databases

PhosphoSitePlusiQ8NGQ6.

Expressioni

Gene expression databases

BgeeiENSG00000172377.
CleanExiHS_OR9I1.
ExpressionAtlasiQ8NGQ6. differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000302606.

Structurei

3D structure databases

ProteinModelPortaliQ8NGQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IPDA. Eukaryota.
ENOG41119U6. LUCA.
GeneTreeiENSGT00810000125445.
HOGENOMiHOG000041364.
HOVERGENiHBG017625.
InParanoidiQ8NGQ6.
KOiK04257.
OMAiMYLQSGS.
OrthoDBiEOG091G0AZH.
PhylomeDBiQ8NGQ6.
TreeFamiTF337111.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF13853. 7tm_4. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NGQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKNNLTRVT EFILMGFMDH PKLEIPLFLV FLSFYLVTLL GNVGMIMLIQ
60 70 80 90 100
VDVKLYTPMY FFLSHLSLLD ACYTSVITPQ ILATLATGKT VISYGHCAAQ
110 120 130 140 150
FFLFTICAGT ECFLLAVMAY DRYAAIRNPL LYTVAMNPRL CWSLVVGAYV
160 170 180 190 200
CGVSGAILRT TCTFTLSFCK DNQINFFFCD LPPLLKLACS DTANIEIVII
210 220 230 240 250
FFGNFVILAN ASVILISYLL IIKTILKVKS SGGRAKTFST CASHITAVAL
260 270 280 290 300
FFGALIFMYL QSGSGKSLEE DKVVSVFYTV VIPMLNPLIY SLRNKDVKDA
310
FRKVARRLQV SLSM
Length:314
Mass (Da):34,908
Last modified:October 1, 2002 - v1
Checksum:iBCB7E6BC6ADA706A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065733 Genomic DNA. Translation: BAC05954.1.
CH471076 Genomic DNA. Translation: EAW73796.1.
AF399531 Genomic DNA. Translation: AAK95016.1.
BK004292 Genomic DNA. Translation: DAA04690.1.
CCDSiCCDS31542.1.
RefSeqiNP_001005211.1. NM_001005211.1.
UniGeneiHs.632122.

Genome annotation databases

EnsembliENST00000302610; ENSP00000302606; ENSG00000172377.
GeneIDi219954.
KEGGihsa:219954.
UCSCiuc001nml.1. human.

Similar proteinsi

Entry informationi

Entry nameiOR9I1_HUMAN
AccessioniPrimary (citable) accession number: Q8NGQ6
Secondary accession number(s): Q6IFH0, Q96RA8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: September 27, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families