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Protein
Submitted name:

Seven transmembrane helix receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported, TransducerSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Seven transmembrane helix receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei68 – 9023HelicalSequence analysisAdd
BLAST
Transmembranei110 – 12819HelicalSequence analysisAdd
BLAST
Transmembranei148 – 17225HelicalSequence analysisAdd
BLAST
Transmembranei205 – 23430HelicalSequence analysisAdd
BLAST
Transmembranei246 – 26823HelicalSequence analysisAdd
BLAST
Transmembranei280 – 30021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8NGM4.
PeptideAtlasiQ8NGM4.
PRIDEiQ8NGM4.

Expressioni

Gene expression databases

BgeeiQ8NGM4.

Structurei

3D structure databases

ProteinModelPortaliQ8NGM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 298250G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IUX9. Eukaryota.
ENOG41115S1. LUCA.
HOGENOMiHOG000041365.
HOVERGENiHBG017625.
InParanoidiQ8NGM4.
OrthoDBiEOG75B85T.
PhylomeDBiQ8NGM4.
TreeFamiTF338157.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NGM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKREINSAF GVKSRYRYLG PLYVIYTYYH IRIILLFTQA PDLDLFPAAN
60 70 80 90 100
VSIMGAIKLS HNLHTPMYFF LCGLSFSETC TTVVVIPRML VDFLSESKTI
110 120 130 140 150
SLPECATQMF FFLGFASNNC FIMAAMSYDR YTAIHNPLQY HTLMTRKICL
160 170 180 190 200
QMMMASWMVG FLFSLCIIVT VFNLSLCDLN TIQHYFCDIS PVVSLACNYT
210 220 230 240 250
FYHEMAIFVL SAFVLVGSCI LIMISYVFIV FIVIKMPSAK GRSKAFSTCS
260 270 280 290 300
SHLTVVSIHY GFACFVYLRP KNSNSFDEDM LTAMIYTILM PLLNPIVYSL
310 320 330
RNKEMQIALR KTLGSVFGVF PQKTKKEPEH LKKLHSIDK
Length:339
Mass (Da):38,778
Last modified:October 1, 2002 - v1
Checksum:iA743039B42097A97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065766 Genomic DNA. Translation: BAC05986.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065766 Genomic DNA. Translation: BAC05986.1.

3D structure databases

ProteinModelPortaliQ8NGM4.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ8NGM4.
PeptideAtlasiQ8NGM4.
PRIDEiQ8NGM4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IUX9. Eukaryota.
ENOG41115S1. LUCA.
HOGENOMiHOG000041365.
HOVERGENiHBG017625.
InParanoidiQ8NGM4.
OrthoDBiEOG75B85T.
PhylomeDBiQ8NGM4.
TreeFamiTF338157.

Gene expression databases

BgeeiQ8NGM4.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
    Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y.
    Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CBRC7TM_329Imported.

Entry informationi

Entry nameiQ8NGM4_HUMAN
AccessioniPrimary (citable) accession number: Q8NGM4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 6, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.