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Protein
Submitted name:

Seven transmembrane helix receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Submitted name:
Seven transmembrane helix receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8NGM4.
PRIDEiQ8NGM4.

Expressioni

Gene expression databases

BgeeiQ8NGM4.

Structurei

3D structure databases

ProteinModelPortaliQ8NGM4.
SMRiQ8NGM4. Positions 49-315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG41862.
HOGENOMiHOG000041365.
HOVERGENiHBG017625.
InParanoidiQ8NGM4.
OrthoDBiEOG75B85T.
PhylomeDBiQ8NGM4.
TreeFamiTF338157.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NGM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKREINSAF GVKSRYRYLG PLYVIYTYYH IRIILLFTQA PDLDLFPAAN
60 70 80 90 100
VSIMGAIKLS HNLHTPMYFF LCGLSFSETC TTVVVIPRML VDFLSESKTI
110 120 130 140 150
SLPECATQMF FFLGFASNNC FIMAAMSYDR YTAIHNPLQY HTLMTRKICL
160 170 180 190 200
QMMMASWMVG FLFSLCIIVT VFNLSLCDLN TIQHYFCDIS PVVSLACNYT
210 220 230 240 250
FYHEMAIFVL SAFVLVGSCI LIMISYVFIV FIVIKMPSAK GRSKAFSTCS
260 270 280 290 300
SHLTVVSIHY GFACFVYLRP KNSNSFDEDM LTAMIYTILM PLLNPIVYSL
310 320 330
RNKEMQIALR KTLGSVFGVF PQKTKKEPEH LKKLHSIDK
Length:339
Mass (Da):38,778
Last modified:October 1, 2002 - v1
Checksum:iA743039B42097A97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065766 Genomic DNA. Translation: BAC05986.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065766 Genomic DNA. Translation: BAC05986.1.

3D structure databases

ProteinModelPortaliQ8NGM4.
SMRiQ8NGM4. Positions 49-315.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ8NGM4.
PRIDEiQ8NGM4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG41862.
HOGENOMiHOG000041365.
HOVERGENiHBG017625.
InParanoidiQ8NGM4.
OrthoDBiEOG75B85T.
PhylomeDBiQ8NGM4.
TreeFamiTF338157.

Miscellaneous databases

NextBioi35541258.

Gene expression databases

BgeeiQ8NGM4.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
    Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y.
    Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CBRC7TM_329Imported.

Entry informationi

Entry nameiQ8NGM4_HUMAN
AccessioniPrimary (citable) accession number: Q8NGM4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 1, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.