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Protein

Olfactory receptor 51T1

Gene

OR51T1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 51T1
Alternative name(s):
Olfactory receptor OR11-26
Gene namesi
Name:OR51T1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:15205. OR51T1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727ExtracellularSequence analysisAdd
BLAST
Transmembranei28 – 4821Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini49 – 568CytoplasmicSequence analysis
Transmembranei57 – 7721Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini78 – 10124ExtracellularSequence analysisAdd
BLAST
Transmembranei102 – 12221Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini123 – 14119CytoplasmicSequence analysisAdd
BLAST
Transmembranei142 – 16221Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini163 – 19836ExtracellularSequence analysisAdd
BLAST
Transmembranei199 – 21921Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini220 – 23920CytoplasmicSequence analysisAdd
BLAST
Transmembranei240 – 26021Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini261 – 27515ExtracellularSequence analysisAdd
BLAST
Transmembranei276 – 29621Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini297 – 32731CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiOR51T1.
DMDMi38372711.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 327327Olfactory receptor 51T1PRO_0000150763Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...)Sequence analysis
Glycosylationi6 – 61N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8NGJ9.
PRIDEiQ8NGJ9.

Expressioni

Gene expression databases

CleanExiHS_OR51T1.
ExpressionAtlasiQ8NGJ9. baseline and differential.

Organism-specific databases

HPAiHPA046877.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369738.

Structurei

3D structure databases

ProteinModelPortaliQ8NGJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJGI. Eukaryota.
ENOG41116W3. LUCA.
GeneTreeiENSGT00840000129672.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
InParanoidiQ8NGJ9.
KOiK04257.
PhylomeDBiQ8NGJ9.
TreeFamiTF342735.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NGJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIFNNTTSS SSNFLLTAFP GLECAHVWIS IPVCCLYTIA LLGNSMIFLV
60 70 80 90 100
IITKRRLHKP MYYFLSMLAA VDLCLTITTL PTVLGVLWFH AREISFKACF
110 120 130 140 150
IQMFFVHAFS LLESSVLVAM AFDRFVAICN PLNYATILTD RMVLVIGLVI
160 170 180 190 200
CIRPAVFLLP LLVAINTVSF HGGHELSHPF CYHPEVIKYT YSKPWISSFW
210 220 230 240 250
GLFLQLYLNG TDVLFILFSY VLILRTVLGI VARKKQQKAL STCVCHICAV
260 270 280 290 300
TIFYVPLISL SLAHRLFHST PRVLCSTLAN IYLLLPPVLN PIIYSLKTKT
310 320
IRQAMFQLLQ SKGSWGFNVR GLRGRWD
Length:327
Mass (Da):36,998
Last modified:October 1, 2002 - v1
Checksum:i357B024140657D44
GO

Sequence cautioni

The sequence DAA04681 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065795 Genomic DNA. Translation: BAC06014.1.
AC011711 Genomic DNA. No translation available.
BK004283 Genomic DNA. Translation: DAA04681.1. Different initiation.
RefSeqiNP_001004759.1. NM_001004759.1.
UniGeneiHs.553804.

Genome annotation databases

EnsembliENST00000322049; ENSP00000322679; ENSG00000176900.
GeneIDi401665.
KEGGihsa:401665.
UCSCiuc010qyp.2. human.

Cross-referencesi

Web resourcesi

Human Olfactory Receptor Data Exploratorium (HORDE)

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065795 Genomic DNA. Translation: BAC06014.1.
AC011711 Genomic DNA. No translation available.
BK004283 Genomic DNA. Translation: DAA04681.1. Different initiation.
RefSeqiNP_001004759.1. NM_001004759.1.
UniGeneiHs.553804.

3D structure databases

ProteinModelPortaliQ8NGJ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369738.

Protein family/group databases

GPCRDBiSearch...

Polymorphism and mutation databases

BioMutaiOR51T1.
DMDMi38372711.

Proteomic databases

PaxDbiQ8NGJ9.
PRIDEiQ8NGJ9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000322049; ENSP00000322679; ENSG00000176900.
GeneIDi401665.
KEGGihsa:401665.
UCSCiuc010qyp.2. human.

Organism-specific databases

CTDi401665.
GeneCardsiOR51T1.
HGNCiHGNC:15205. OR51T1.
HPAiHPA046877.
neXtProtiNX_Q8NGJ9.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJGI. Eukaryota.
ENOG41116W3. LUCA.
GeneTreeiENSGT00840000129672.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
InParanoidiQ8NGJ9.
KOiK04257.
PhylomeDBiQ8NGJ9.
TreeFamiTF342735.

Enzyme and pathway databases

ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Miscellaneous databases

GeneWikiiOR51T1.
GenomeRNAii401665.
PROiQ8NGJ9.

Gene expression databases

CleanExiHS_OR51T1.
ExpressionAtlasiQ8NGJ9. baseline and differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO51T1_HUMAN
AccessioniPrimary (citable) accession number: Q8NGJ9
Secondary accession number(s): Q6IFH9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.