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Protein

Putative olfactory receptor 56B2

Gene

OR56B2P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative olfactory receptor 56B2
Gene namesi
Name:OR56B2P
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:15246. OR56B2P.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34ExtracellularSequence analysisAdd BLAST34
Transmembranei35 – 55Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini56 – 63CytoplasmicSequence analysis8
Transmembranei64 – 84Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini85 – 108ExtracellularSequence analysisAdd BLAST24
Transmembranei109 – 129Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini130 – 148CytoplasmicSequence analysisAdd BLAST19
Transmembranei149 – 169Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini170 – 205ExtracellularSequence analysisAdd BLAST36
Transmembranei206 – 226Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini227 – 246CytoplasmicSequence analysisAdd BLAST20
Transmembranei247 – 267Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini268 – 281ExtracellularSequence analysisAdd BLAST14
Transmembranei282 – 302Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini303 – 322CytoplasmicSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi38372699.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001507971 – 322Putative olfactory receptor 56B2Add BLAST322

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi12N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi106 ↔ 198PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PeptideAtlasiQ8NGI1.
PRIDEiQ8NGI1.

Structurei

3D structure databases

ProteinModelPortaliQ8NGI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG017625.
InParanoidiQ8NGI1.
PhylomeDBiQ8NGI1.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF13853. 7tm_4. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8NGI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVVLQELRD SNSSKFQVSE FILMGFPGIH SWQHWLSLPL ALLYLLALSA
60 70 80 90 100
NILILIIINK EAALHQPMYY FLGILAMADI GLATTIMPKI LAILWFNAKT
110 120 130 140 150
ISLLECFAQM YAIHCFVAME SSTFVCMAID RYVAICRPLR YPSIITESFV
160 170 180 190 200
FKANGFMALR NSLCLISVPL LAAQRHYCSQ NQIEHCLCSN LGVTSLSCDD
210 220 230 240 250
RRINSINQVL LAWTLMGSDL GLIILSYALI LYSVLKLNSP EAASKALSTC
260 270 280 290 300
TSHLILILFF YTVIIVISIT RSTGMRVPLI PVLLNVLHNV IPPALNPMVY
310 320
ALKNKELRQG LYKVLRLGVK GT
Length:322
Mass (Da):35,955
Last modified:October 1, 2002 - v1
Checksum:iCFA12F613D1EEF5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB065814 Genomic DNA. Translation: BAC06033.1.

Similar proteinsi

Entry informationi

Entry nameiO56B2_HUMAN
AccessioniPrimary (citable) accession number: Q8NGI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2002
Last modified: August 30, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families