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Protein
Submitted name:

Putative nudix hydrolyase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ADP-sugar diphosphatase activity Source: UniProtKB
  • calcium activated cation channel activity Source: UniProtKB
  • lyase activity Source: UniProtKB-KW

GO - Biological processi

  • cation transmembrane transport Source: GOC
  • cation transport Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported, LyaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Putative nudix hydrolyaseImported (EC:3.6.1.-Imported)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31842.

PTM / Processingi

Proteomic databases

PaxDbiQ8NG26.
PRIDEiQ8NG26.

Expressioni

Gene expression databases

GenevisibleiQ8NG26. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000303575.

Structurei

3D structure databases

ProteinModelPortaliQ8NG26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini128 – 284157Nudix hydrolaseInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili182 – 20928Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4195. Eukaryota.
ENOG410XPYY. LUCA.
HOGENOMiHOG000130166.
HOVERGENiHBG052693.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NG26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGSNGSKEN SHNKARTSPY PGSKVERSQV PNEKVGWLVE WQDYKPVEYT
60 70 80 90 100
AVSVLAGPRW ADPQISEGNF SPKFNEKDGH VERKSKNGLY EIENGRPRNP
110 120 130 140 150
AGRTGLVGRG LLGRWGPNHA ADPIITRWKR DSSGNKIMHP VSGKHILQFV
160 170 180 190 200
AIKRKDCGEW AIPGGMVDPG EKISATLKRE FGEEALNSLQ KTSAEKREIE
210 220 230 240 250
EKLHKLFSQD HLVIYKGYVD DPRNTDNAWM ETEAVNYHDE TGEIMDNLML
260 270 280 290 300
EAGDDAGKVK WVDINDKLKL YASHSQFIKL VAEKRDAHWS EDSEADCHAL
Length:300
Mass (Da):33,746
Last modified:October 1, 2002 - v1
Checksum:i9C35210C703657AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF265341 mRNA. Translation: AAM46066.1.
RefSeqiNP_932155.1. NM_198038.2.
UniGeneiHs.149500.

Genome annotation databases

GeneIDi53343.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF265341 mRNA. Translation: AAM46066.1.
RefSeqiNP_932155.1. NM_198038.2.
UniGeneiHs.149500.

3D structure databases

ProteinModelPortaliQ8NG26.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000303575.

Proteomic databases

PaxDbiQ8NG26.
PRIDEiQ8NG26.

Protocols and materials databases

DNASUi53343.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi53343.

Organism-specific databases

CTDi53343.
PharmGKBiPA31842.

Phylogenomic databases

eggNOGiKOG4195. Eukaryota.
ENOG410XPYY. LUCA.
HOGENOMiHOG000130166.
HOVERGENiHBG052693.

Miscellaneous databases

GenomeRNAii53343.

Gene expression databases

GenevisibleiQ8NG26. HS.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A Novel Human 'Nudix' Hydrolyase Gene, Cloning, Expression Analysis and Genome Localization."
    Lin S., Ying K., Xie Y., Mao Y.
    Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ8NG26_HUMAN
AccessioniPrimary (citable) accession number: Q8NG26
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.