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Protein
Submitted name:

Argininosuccinate synthetase

Gene

ASS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: InterPro
  2. ATP binding Source: InterPro
  3. toxic substance binding Source: Ensembl

GO - Biological processi

  1. acute-phase response Source: Ensembl
  2. aging Source: Ensembl
  3. arginine biosynthetic process Source: InterPro
  4. argininosuccinate metabolic process Source: Ensembl
  5. cellular response to amine stimulus Source: Ensembl
  6. cellular response to amino acid stimulus Source: Ensembl
  7. cellular response to ammonium ion Source: Ensembl
  8. cellular response to cAMP Source: Ensembl
  9. cellular response to dexamethasone stimulus Source: Ensembl
  10. cellular response to glucagon stimulus Source: Ensembl
  11. cellular response to interferon-gamma Source: Ensembl
  12. cellular response to lipopolysaccharide Source: Ensembl
  13. cellular response to oleic acid Source: Ensembl
  14. cellular response to tumor necrosis factor Source: Ensembl
  15. diaphragm development Source: Ensembl
  16. kidney development Source: Ensembl
  17. liver development Source: Ensembl
  18. midgut development Source: Ensembl
  19. response to drug Source: Ensembl
  20. response to estradiol Source: Ensembl
  21. response to growth hormone Source: Ensembl
  22. response to mycotoxin Source: Ensembl
  23. response to nutrient Source: Ensembl
  24. response to zinc ion Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Argininosuccinate synthetaseImported
Gene namesi
Name:ASSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cell body fiber Source: Ensembl
  2. endoplasmic reticulum Source: Ensembl
  3. lysosome Source: Ensembl
  4. mitochondrial outer membrane Source: Ensembl
  5. nucleus Source: Ensembl
  6. perikaryon Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8NFZ7.

Expressioni

Gene expression databases

BgeeiQ8NFZ7.
ExpressionAtlasiQ8NFZ7. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di3.90.1260.10. 1 hit.
InterProiIPR001518. Arginosuc_synth.
IPR024074. AS_cat/multimer_dom_body.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8NFZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
QHGIPIPVTP KNPWSMDENL MHI
Length:23
Mass (Da):2,655
Last modified:October 1, 2002 - v1
Checksum:i45FFDF3925FD77D0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei23 – 231Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF363662 Genomic DNA. Translation: AAM60751.1.
UniGeneiHs.160786.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF363662 Genomic DNA. Translation: AAM60751.1.
UniGeneiHs.160786.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ8NFZ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ8NFZ7.
ExpressionAtlasiQ8NFZ7. baseline and differential.

Family and domain databases

Gene3Di3.90.1260.10. 1 hit.
InterProiIPR001518. Arginosuc_synth.
IPR024074. AS_cat/multimer_dom_body.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Human ASS exon 7."
    Haeberle J., Linnebank M., Pauli S., Harms E., Koch H.G.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8NFZ7_HUMAN
AccessioniPrimary (citable) accession number: Q8NFZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 26, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.