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Q8NFY4

- SEM6D_HUMAN

UniProt

Q8NFY4 - SEM6D_HUMAN

Protein

Semaphorin-6D

Gene

SEMA6D

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
    • BLAST
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.

    GO - Molecular functioni

    1. receptor activity Source: InterPro

    GO - Biological processi

    1. axon guidance Source: Reactome
    2. negative regulation of smooth muscle cell migration Source: Ensembl
    3. positive regulation of smooth muscle cell migration Source: Ensembl
    4. ventricular system development Source: Ensembl

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Neurogenesis

    Enzyme and pathway databases

    ReactomeiREACT_19200. Other semaphorin interactions.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Semaphorin-6D
    Gene namesi
    Name:SEMA6D
    Synonyms:KIAA1479
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:16770. SEMA6D.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Cytoplasm, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134951035.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 10731053Semaphorin-6DPRO_0000044615Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi51 – 511N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi108 ↔ 118PROSITE-ProRule annotation
    Disulfide bondi136 ↔ 145PROSITE-ProRule annotation
    Disulfide bondi259 ↔ 370PROSITE-ProRule annotation
    Glycosylationi283 – 2831N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi284 ↔ 329PROSITE-ProRule annotation
    Glycosylationi435 – 4351N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi461 – 4611N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi477 ↔ 506PROSITE-ProRule annotation
    Disulfide bondi515 ↔ 533PROSITE-ProRule annotation
    Disulfide bondi521 ↔ 568PROSITE-ProRule annotation
    Disulfide bondi525 ↔ 541PROSITE-ProRule annotation
    Glycosylationi631 – 6311N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    MaxQBiQ8NFY4.
    PaxDbiQ8NFY4.
    PRIDEiQ8NFY4.

    PTM databases

    PhosphoSiteiQ8NFY4.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8NFY4.
    BgeeiQ8NFY4.
    GenevestigatoriQ8NFY4.

    Organism-specific databases

    HPAiHPA043109.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NFY4.
    SMRiQ8NFY4. Positions 23-533.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini21 – 662642ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini684 – 1073390CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei663 – 68321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini27 – 512486SemaPROSITE-ProRule annotationAdd
    BLAST
    Domaini514 – 56956PSIAdd
    BLAST

    Sequence similaritiesi

    Belongs to the semaphorin family.Curated
    Contains 1 PSI domain.Curated
    Contains 1 Sema domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG293968.
    HOGENOMiHOG000232047.
    HOVERGENiHBG072910.
    InParanoidiQ8NFY4.
    KOiK06842.
    OMAiCVFAAFV.
    OrthoDBiEOG7SV0TJ.
    PhylomeDBiQ8NFY4.
    TreeFamiTF316102.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR016201. Plexin-like_fold.
    IPR002165. Plexin_repeat.
    IPR001627. Semap_dom.
    IPR027231. Semaphorin.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view]
    PANTHERiPTHR11036. PTHR11036. 1 hit.
    PfamiPF01437. PSI. 1 hit.
    PF01403. Sema. 1 hit.
    [Graphical view]
    SMARTiSM00423. PSI. 1 hit.
    SM00630. Sema. 1 hit.
    [Graphical view]
    SUPFAMiSSF101912. SSF101912. 1 hit.
    SSF103575. SSF103575. 1 hit.
    PROSITEiPS51004. SEMA. 1 hit.
    [Graphical view]

    Sequences (8)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 8 isoformsi produced by alternative splicing. Align

    Isoform 4 (identifier: Q8NFY4-1) [UniParc]FASTAAdd to Basket

    Also known as: SEMA6D.4

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MRVFLLCAYI LLLMVSQLRA VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG     50
    NESQHRLDFQ LMLKIRDTLY IAGRDQVYTV NLNEMPKTEV IPNKKLTWRS 100
    RQQDRENCAM KGKHKDECHN FIKVFVPRND EMVFVCGTNA FNPMCRYYRL 150
    STLEYDGEEI SGLARCPFDA RQTNVALFAD GKLYSATVAD FLASDAVIYR 200
    SMGDGSALRT IKYDSKWIKE PHFLHAIEYG NYVYFFFREI AVEHNNLGKA 250
    VYSRVARICK NDMGGSQRVL EKHWTSFLKA RLNCSVPGDS FFYFDVLQSI 300
    TDIIQINGIP TVVGVFTTQL NSIPGSAVCA FSMDDIEKVF KGRFKEQKTP 350
    DSVWTAVPED KVPKPRPGCC AKHGLAEAYK TSIDFPDETL SFIKSHPLMD 400
    SAVPPIADEP WFTKTRVRYR LTAISVDHSA GPYQNYTVIF VGSEAGMVLK 450
    VLAKTSPFSL NDSVLLEEIE AYNHAKCSAE NEEDKKVISL QLDKDHHALY 500
    VAFSSCIIRI PLSRCERYGS CKKSCIASRD PYCGWLSQGS CGRVTPGMLA 550
    EGYEQDTEFG NTAHLGDCHE ILPTSTTPDY KIFGGPTSDM EVSSSSVTTM 600
    ASIPEITPKV IDTWRPKLTS SRKFVVQDDP NTSDFTDPLS GIPKGVRWEV 650
    QSGESNQMVH MNVLITCVFA AFVLGAFIAG VAVYCYRDMF VRKNRKIHKD 700
    AESAQSCTDS SGSFAKLNGL FDSPVKEYQQ NIDSPKLYSN LLTSRKELPP 750
    NGDTKSMVMD HRGQPPELAA LPTPESTPVL HQKTLQAMKS HSEKAHGHGA 800
    SRKETPQFFP SSPPPHSPLS HGHIPSAIVL PNATHDYNTS FSNSNAHKAE 850
    KKLQNIDHPL TKSSSKRDHR RSVDSRNTLN DLLKHLNDPN SNPKAIMGDI 900
    QMAHQNLMLD PMGSMSEVPP KVPNREASLY SPPSTLPRNS PTKRVDVPTT 950
    PGVPMTSLER QRGYHKNSSQ RHSISAMPKN LNSPNGVLLS RQPSMNRGGY 1000
    MPTPTGAKVD YIQGTPVSVH LQPSLSRQSS YTSNGTLPRT GLKRTPSLKP 1050
    DVPPKPSFVP QTPSVRPLNK YTY 1073
    Length:1,073
    Mass (Da):119,872
    Last modified:October 1, 2002 - v1
    Checksum:i7DCE4DFC5BF70F9E
    GO
    Isoform 1 (identifier: Q8NFY4-2) [UniParc]FASTAAdd to Basket

    Also known as: SEMA6D.1

    The sequence of this isoform differs from the canonical sequence as follows:
         549-549: L → LLLTEDFFAFHNHS
         570-644: Missing.

    Show »
    Length:1,011
    Mass (Da):113,290
    Checksum:i9D6B8B3633941B89
    GO
    Isoform 2 (identifier: Q8NFY4-3) [UniParc]FASTAAdd to Basket

    Also known as: SEMA6D.2

    The sequence of this isoform differs from the canonical sequence as follows:
         570-644: Missing.

    Show »
    Length:998
    Mass (Da):111,730
    Checksum:i3F46D6872E8D5344
    GO
    Isoform 3 (identifier: Q8NFY4-4) [UniParc]FASTAAdd to Basket

    Also known as: SEMA6D.3

    The sequence of this isoform differs from the canonical sequence as follows:
         589-644: Missing.

    Show »
    Length:1,017
    Mass (Da):113,736
    Checksum:i4D639CEBADD9F2A0
    GO
    Isoform 5 (identifier: Q8NFY4-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         549-549: L → LLLTEDFFAFHNHS
         589-644: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,030
    Mass (Da):115,296
    Checksum:i659CF8EA114B048F
    GO
    Isoform 6 (identifier: Q8NFY4-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         570-588: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,054
    Mass (Da):117,866
    Checksum:iA888C403FFACEE8F
    GO
    Isoform 7 (identifier: Q8NFY4-7) [UniParc]FASTAAdd to Basket

    Also known as: SEMA6Ds, Short

    The sequence of this isoform differs from the canonical sequence as follows:
         477-1073: Missing.

    Show »
    Length:476
    Mass (Da):54,217
    Checksum:i3AAB6E77051D2D83
    GO
    Isoform 8 (identifier: Q8NFY4-8) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         570-588: Missing.
         601-1073: ASIPEITPKV...SVRPLNKYTY → VYDGKSSLESPTRWST

    Note: No experimental confirmation available. Gene prediction based on mRNA data.

    Show »
    Length:597
    Mass (Da):67,538
    Checksum:i58D3EE7B6B68DB67
    GO

    Sequence cautioni

    The sequence BAA96003.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti307 – 3071N → S.
    Corresponds to variant rs3743279 [ dbSNP | Ensembl ].
    VAR_051931
    Natural varianti478 – 4781S → N.
    Corresponds to variant rs532598 [ dbSNP | Ensembl ].
    VAR_051932
    Natural varianti969 – 9691S → T.
    Corresponds to variant rs16960074 [ dbSNP | Ensembl ].
    VAR_051933

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei477 – 1073597Missing in isoform 7. 1 PublicationVSP_016564Add
    BLAST
    Alternative sequencei549 – 5491L → LLLTEDFFAFHNHS in isoform 1 and isoform 5. 3 PublicationsVSP_016565
    Alternative sequencei570 – 64475Missing in isoform 1 and isoform 2. 3 PublicationsVSP_016566Add
    BLAST
    Alternative sequencei570 – 58819Missing in isoform 6 and isoform 8. CuratedVSP_016572Add
    BLAST
    Alternative sequencei589 – 64456Missing in isoform 3 and isoform 5. 1 PublicationVSP_016567Add
    BLAST
    Alternative sequencei601 – 1073473ASIPE…NKYTY → VYDGKSSLESPTRWST in isoform 8. CuratedVSP_054084Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF389426 mRNA. Translation: AAM69449.1.
    AF389427 mRNA. Translation: AAM69450.1.
    AF389428 mRNA. Translation: AAM69451.1.
    AF389429 mRNA. Translation: AAM69452.1.
    AF389430 mRNA. Translation: AAM69453.1.
    AB040912 mRNA. Translation: BAA96003.2. Different initiation.
    AC018900 Genomic DNA. No translation available.
    AC044787 Genomic DNA. No translation available.
    AC009558 Genomic DNA. No translation available.
    AC012050 Genomic DNA. No translation available.
    AC023905 Genomic DNA. No translation available.
    AC066615 Genomic DNA. No translation available.
    AC084882 Genomic DNA. No translation available.
    BC150253 mRNA. Translation: AAI50254.1.
    CCDSiCCDS32224.1. [Q8NFY4-2]
    CCDS32225.1. [Q8NFY4-1]
    CCDS32226.1. [Q8NFY4-4]
    CCDS32227.1. [Q8NFY4-3]
    CCDS32228.1. [Q8NFY4-8]
    CCDS32229.1. [Q8NFY4-7]
    RefSeqiNP_001185928.1. NM_001198999.1. [Q8NFY4-2]
    NP_065909.1. NM_020858.1. [Q8NFY4-2]
    NP_079242.2. NM_024966.2. [Q8NFY4-7]
    NP_705869.1. NM_153616.1. [Q8NFY4-3]
    NP_705870.1. NM_153617.1. [Q8NFY4-4]
    NP_705871.1. NM_153618.1. [Q8NFY4-1]
    NP_705872.1. NM_153619.1. [Q8NFY4-8]
    XP_005254744.1. XM_005254687.1. [Q8NFY4-1]
    XP_005254746.1. XM_005254689.1. [Q8NFY4-6]
    XP_005254747.1. XM_005254690.1. [Q8NFY4-5]
    UniGeneiHs.511265.

    Genome annotation databases

    EnsembliENST00000316364; ENSP00000324857; ENSG00000137872. [Q8NFY4-1]
    ENST00000354744; ENSP00000346786; ENSG00000137872. [Q8NFY4-4]
    ENST00000355997; ENSP00000348276; ENSG00000137872. [Q8NFY4-8]
    ENST00000358066; ENSP00000350770; ENSG00000137872. [Q8NFY4-2]
    ENST00000389425; ENSP00000374076; ENSG00000137872. [Q8NFY4-7]
    ENST00000389428; ENSP00000374079; ENSG00000137872. [Q8NFY4-3]
    ENST00000536845; ENSP00000446152; ENSG00000137872. [Q8NFY4-1]
    ENST00000537942; ENSP00000442040; ENSG00000137872. [Q8NFY4-2]
    ENST00000558014; ENSP00000452815; ENSG00000137872. [Q8NFY4-2]
    ENST00000558816; ENSP00000453661; ENSG00000137872. [Q8NFY4-8]
    GeneIDi80031.
    KEGGihsa:80031.
    UCSCiuc001zvw.3. human. [Q8NFY4-2]
    uc001zvx.1. human. [Q8NFY4-7]
    uc001zvy.3. human. [Q8NFY4-1]
    uc001zvz.3. human. [Q8NFY4-4]
    uc001zwc.3. human. [Q8NFY4-3]

    Polymorphism databases

    DMDMi74715611.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF389426 mRNA. Translation: AAM69449.1 .
    AF389427 mRNA. Translation: AAM69450.1 .
    AF389428 mRNA. Translation: AAM69451.1 .
    AF389429 mRNA. Translation: AAM69452.1 .
    AF389430 mRNA. Translation: AAM69453.1 .
    AB040912 mRNA. Translation: BAA96003.2 . Different initiation.
    AC018900 Genomic DNA. No translation available.
    AC044787 Genomic DNA. No translation available.
    AC009558 Genomic DNA. No translation available.
    AC012050 Genomic DNA. No translation available.
    AC023905 Genomic DNA. No translation available.
    AC066615 Genomic DNA. No translation available.
    AC084882 Genomic DNA. No translation available.
    BC150253 mRNA. Translation: AAI50254.1 .
    CCDSi CCDS32224.1. [Q8NFY4-2 ]
    CCDS32225.1. [Q8NFY4-1 ]
    CCDS32226.1. [Q8NFY4-4 ]
    CCDS32227.1. [Q8NFY4-3 ]
    CCDS32228.1. [Q8NFY4-8 ]
    CCDS32229.1. [Q8NFY4-7 ]
    RefSeqi NP_001185928.1. NM_001198999.1. [Q8NFY4-2 ]
    NP_065909.1. NM_020858.1. [Q8NFY4-2 ]
    NP_079242.2. NM_024966.2. [Q8NFY4-7 ]
    NP_705869.1. NM_153616.1. [Q8NFY4-3 ]
    NP_705870.1. NM_153617.1. [Q8NFY4-4 ]
    NP_705871.1. NM_153618.1. [Q8NFY4-1 ]
    NP_705872.1. NM_153619.1. [Q8NFY4-8 ]
    XP_005254744.1. XM_005254687.1. [Q8NFY4-1 ]
    XP_005254746.1. XM_005254689.1. [Q8NFY4-6 ]
    XP_005254747.1. XM_005254690.1. [Q8NFY4-5 ]
    UniGenei Hs.511265.

    3D structure databases

    ProteinModelPortali Q8NFY4.
    SMRi Q8NFY4. Positions 23-533.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8NFY4.

    Polymorphism databases

    DMDMi 74715611.

    Proteomic databases

    MaxQBi Q8NFY4.
    PaxDbi Q8NFY4.
    PRIDEi Q8NFY4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000316364 ; ENSP00000324857 ; ENSG00000137872 . [Q8NFY4-1 ]
    ENST00000354744 ; ENSP00000346786 ; ENSG00000137872 . [Q8NFY4-4 ]
    ENST00000355997 ; ENSP00000348276 ; ENSG00000137872 . [Q8NFY4-8 ]
    ENST00000358066 ; ENSP00000350770 ; ENSG00000137872 . [Q8NFY4-2 ]
    ENST00000389425 ; ENSP00000374076 ; ENSG00000137872 . [Q8NFY4-7 ]
    ENST00000389428 ; ENSP00000374079 ; ENSG00000137872 . [Q8NFY4-3 ]
    ENST00000536845 ; ENSP00000446152 ; ENSG00000137872 . [Q8NFY4-1 ]
    ENST00000537942 ; ENSP00000442040 ; ENSG00000137872 . [Q8NFY4-2 ]
    ENST00000558014 ; ENSP00000452815 ; ENSG00000137872 . [Q8NFY4-2 ]
    ENST00000558816 ; ENSP00000453661 ; ENSG00000137872 . [Q8NFY4-8 ]
    GeneIDi 80031.
    KEGGi hsa:80031.
    UCSCi uc001zvw.3. human. [Q8NFY4-2 ]
    uc001zvx.1. human. [Q8NFY4-7 ]
    uc001zvy.3. human. [Q8NFY4-1 ]
    uc001zvz.3. human. [Q8NFY4-4 ]
    uc001zwc.3. human. [Q8NFY4-3 ]

    Organism-specific databases

    CTDi 80031.
    GeneCardsi GC15P047476.
    HGNCi HGNC:16770. SEMA6D.
    HPAi HPA043109.
    MIMi 609295. gene.
    neXtProti NX_Q8NFY4.
    PharmGKBi PA134951035.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG293968.
    HOGENOMi HOG000232047.
    HOVERGENi HBG072910.
    InParanoidi Q8NFY4.
    KOi K06842.
    OMAi CVFAAFV.
    OrthoDBi EOG7SV0TJ.
    PhylomeDBi Q8NFY4.
    TreeFami TF316102.

    Enzyme and pathway databases

    Reactomei REACT_19200. Other semaphorin interactions.

    Miscellaneous databases

    GenomeRNAii 80031.
    NextBioi 70190.
    PROi Q8NFY4.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8NFY4.
    Bgeei Q8NFY4.
    Genevestigatori Q8NFY4.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR016201. Plexin-like_fold.
    IPR002165. Plexin_repeat.
    IPR001627. Semap_dom.
    IPR027231. Semaphorin.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view ]
    PANTHERi PTHR11036. PTHR11036. 1 hit.
    Pfami PF01437. PSI. 1 hit.
    PF01403. Sema. 1 hit.
    [Graphical view ]
    SMARTi SM00423. PSI. 1 hit.
    SM00630. Sema. 1 hit.
    [Graphical view ]
    SUPFAMi SSF101912. SSF101912. 1 hit.
    SSF103575. SSF103575. 1 hit.
    PROSITEi PS51004. SEMA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification, characterization, and functional study of the two novel human members of the semaphorin gene family."
      Qu X., Wei H., Zhai Y., Que H., Chen Q., Tang F., Wu Y., Xing G., Zhu Y., Liu S., Fan M., He F.
      J. Biol. Chem. 277:35574-35585(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4 AND 7), SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
      Tissue: Brain.
    2. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
      DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.
    4. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).

    Entry informationi

    Entry nameiSEM6D_HUMAN
    AccessioniPrimary (citable) accession number: Q8NFY4
    Secondary accession number(s): A6NF10
    , A6NM95, A6NNK1, A7E2A0, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3