Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8NFI9

- Q8NFI9_HUMAN

UniProt

Q8NFI9 - Q8NFI9_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Fibroblast growth factor

Gene

FGF10

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chemoattractant activity Source: Ensembl

GO - Biological processi

  1. angiogenesis Source: Ensembl
  2. blood vessel remodeling Source: Ensembl
  3. branch elongation involved in salivary gland morphogenesis Source: Ensembl
  4. bronchiole morphogenesis Source: Ensembl
  5. bud elongation involved in lung branching Source: Ensembl
  6. determination of left/right symmetry Source: Ensembl
  7. embryonic camera-type eye development Source: Ensembl
  8. embryonic digestive tract morphogenesis Source: Ensembl
  9. embryonic genitalia morphogenesis Source: Ensembl
  10. embryonic pattern specification Source: Ensembl
  11. epithelial cell migration Source: Ensembl
  12. epithelial cell proliferation involved in salivary gland morphogenesis Source: Ensembl
  13. establishment of mitotic spindle orientation Source: Ensembl
  14. female genitalia morphogenesis Source: Ensembl
  15. fibroblast growth factor receptor signaling pathway involved in mammary gland specification Source: Ensembl
  16. hair follicle morphogenesis Source: Ensembl
  17. Harderian gland development Source: Ensembl
  18. induction of positive chemotaxis Source: Ensembl
  19. keratinocyte proliferation Source: Ensembl
  20. limb bud formation Source: Ensembl
  21. lung alveolus development Source: Ensembl
  22. lung proximal/distal axis specification Source: Ensembl
  23. male genitalia morphogenesis Source: Ensembl
  24. mammary gland bud formation Source: Ensembl
  25. mesenchymal cell differentiation involved in lung development Source: Ensembl
  26. mesenchymal-epithelial cell signaling involved in lung development Source: Ensembl
  27. metanephros morphogenesis Source: Ensembl
  28. muscle cell fate commitment Source: Ensembl
  29. negative regulation of cell proliferation Source: Ensembl
  30. negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
  31. odontogenesis of dentin-containing tooth Source: Ensembl
  32. organ growth Source: Ensembl
  33. organ induction Source: Ensembl
  34. otic vesicle formation Source: Ensembl
  35. pancreas development Source: Ensembl
  36. pituitary gland development Source: Ensembl
  37. positive regulation of canonical Wnt signaling pathway Source: Ensembl
  38. positive regulation of epithelial cell migration Source: Ensembl
  39. positive regulation of epithelial cell proliferation Source: Ensembl
  40. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
  41. positive regulation of fibroblast proliferation Source: Ensembl
  42. positive regulation of mitotic cell cycle Source: Ensembl
  43. positive regulation of Notch signaling pathway Source: Ensembl
  44. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  45. positive regulation of vascular endothelial growth factor receptor signaling pathway Source: Ensembl
  46. positive regulation of white fat cell proliferation Source: Ensembl
  47. prostatic bud formation Source: Ensembl
  48. radial glial cell differentiation Source: Ensembl
  49. regulation of activin receptor signaling pathway Source: Ensembl
  50. regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling Source: Ensembl
  51. regulation of smoothened signaling pathway Source: Ensembl
  52. response to estradiol Source: Ensembl
  53. response to lipopolysaccharide Source: Ensembl
  54. semicircular canal fusion Source: Ensembl
  55. smooth muscle cell differentiation Source: Ensembl
  56. somatic stem cell maintenance Source: Ensembl
  57. spleen development Source: Ensembl
  58. submandibular salivary gland formation Source: Ensembl
  59. thyroid gland development Source: Ensembl
  60. tissue regeneration Source: Ensembl
  61. Type II pneumocyte differentiation Source: Ensembl
  62. white fat cell differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fibroblast growth factorUniRule annotation
Short name:
FGFUniRule annotation
Gene namesi
Name:FGF10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8NFI9.
ExpressionAtlasiQ8NFI9. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the heparin-binding growth factors family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG007580.

Family and domain databases

InterProiIPR008996. Cytokine_IL1-like.
IPR028252. FGF10.
IPR002209. Fibroblast_GF_fam.
IPR028142. IL-1_fam/FGF_fam.
[Graphical view]
PANTHERiPTHR11486. PTHR11486. 1 hit.
PTHR11486:SF21. PTHR11486:SF21. 1 hit.
PRINTSiPR00263. HBGFFGF.
PR00262. IL1HBGF.
SMARTiSM00442. FGF. 1 hit.
[Graphical view]
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiPS00247. HBGF_FGF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8NFI9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ALGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY
60 70 80 90 100
FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG
110 120 130 140 150
KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR
160 170
GQKTRRKNTS AHFLPMVVHS
Length:170
Mass (Da):19,195
Last modified:October 1, 2002 - v1
Checksum:i4EA43515F758327A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF508782 mRNA. Translation: AAM46926.1.
UniGeneiHs.664499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF508782 mRNA. Translation: AAM46926.1 .
UniGenei Hs.664499.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG007580.

Gene expression databases

Bgeei Q8NFI9.
ExpressionAtlasi Q8NFI9. baseline and differential.

Family and domain databases

InterProi IPR008996. Cytokine_IL1-like.
IPR028252. FGF10.
IPR002209. Fibroblast_GF_fam.
IPR028142. IL-1_fam/FGF_fam.
[Graphical view ]
PANTHERi PTHR11486. PTHR11486. 1 hit.
PTHR11486:SF21. PTHR11486:SF21. 1 hit.
PRINTSi PR00263. HBGFFGF.
PR00262. IL1HBGF.
SMARTi SM00442. FGF. 1 hit.
[Graphical view ]
SUPFAMi SSF50353. SSF50353. 1 hit.
PROSITEi PS00247. HBGF_FGF. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BladderImported.

Entry informationi

Entry nameiQ8NFI9_HUMAN
AccessioniPrimary (citable) accession number: Q8NFI9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.