Q8NFI9 (Q8NFI9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fibroblast growth factor 10 EMBL AAM46926.1

Gene names

Name:

FGF10 EMBL AAM46926.1

Organism

Homo sapiens (Human) EMBL AAM46926.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	170 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	Harderian gland development Inferred from electronic annotation. Source: Compara Type II pneumocyte differentiation Inferred from electronic annotation. Source: Compara angiogenesis Inferred from electronic annotation. Source: Compara blood vessel remodeling Inferred from electronic annotation. Source: Compara branch elongation involved in salivary gland morphogenesis Inferred from electronic annotation. Source: Compara bronchiole morphogenesis Inferred from electronic annotation. Source: Compara determination of left/right symmetry Inferred from electronic annotation. Source: Compara embryonic camera-type eye development Inferred from electronic annotation. Source: Compara embryonic digestive tract morphogenesis Inferred from electronic annotation. Source: Compara embryonic genitalia morphogenesis Inferred from electronic annotation. Source: Compara embryonic pattern specification Inferred from electronic annotation. Source: Compara epithelial cell migration Inferred from electronic annotation. Source: Compara epithelial cell proliferation involved in salivary gland morphogenesis Inferred from electronic annotation. Source: Compara epithelial tube branching involved in lung morphogenesis Inferred from electronic annotation. Source: Compara female genitalia morphogenesis Inferred from electronic annotation. Source: Compara fibroblast growth factor receptor signaling pathway involved in mammary gland specification Inferred from electronic annotation. Source: Compara hair follicle morphogenesis Inferred from electronic annotation. Source: Compara induction of positive chemotaxis Inferred from electronic annotation. Source: Compara keratinocyte proliferation Inferred from electronic annotation. Source: Compara lacrimal gland development Inferred from electronic annotation. Source: Compara limb bud formation Inferred from electronic annotation. Source: Compara lung alveolus development Inferred from electronic annotation. Source: Compara lung proximal/distal axis specification Inferred from electronic annotation. Source: Compara male genitalia morphogenesis Inferred from electronic annotation. Source: Compara mammary gland bud formation Inferred from electronic annotation. Source: Compara mesenchymal cell differentiation involved in lung development Inferred from electronic annotation. Source: Compara mesenchymal-epithelial cell signaling involved in lung development Inferred from electronic annotation. Source: Compara metanephros morphogenesis Inferred from electronic annotation. Source: Compara muscle cell fate commitment Inferred from electronic annotation. Source: Compara negative regulation of apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara odontogenesis of dentin-containing tooth Inferred from electronic annotation. Source: Compara organ growth Inferred from electronic annotation. Source: Compara organ induction Inferred from electronic annotation. Source: Compara otic vesicle formation Inferred from electronic annotation. Source: Compara pancreas development Inferred from electronic annotation. Source: Compara pituitary gland development Inferred from electronic annotation. Source: Compara positive regulation of ERK1 and ERK2 cascade Inferred from electronic annotation. Source: Compara positive regulation of Notch signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell migration Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of mitotic cell cycle Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of vascular endothelial growth factor receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of white fat cell proliferation Inferred from electronic annotation. Source: Compara radial glial cell differentiation Inferred from electronic annotation. Source: Compara regulation of activin receptor signaling pathway Inferred from electronic annotation. Source: Compara regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling Inferred from electronic annotation. Source: Compara regulation of prostatic bud formation Inferred from electronic annotation. Source: Compara regulation of smoothened signaling pathway Inferred from electronic annotation. Source: Compara response to estradiol stimulus Inferred from electronic annotation. Source: Compara response to lipopolysaccharide Inferred from electronic annotation. Source: Compara semicircular canal fusion Inferred from electronic annotation. Source: Compara smooth muscle cell differentiation Inferred from electronic annotation. Source: Compara somatic stem cell maintenance Inferred from electronic annotation. Source: Compara spleen development Inferred from electronic annotation. Source: Compara submandibular salivary gland formation Inferred from electronic annotation. Source: Compara thyroid gland development Inferred from electronic annotation. Source: Compara tissue regeneration Inferred from electronic annotation. Source: Compara white fat cell differentiation Inferred from electronic annotation. Source: Compara
Cellular_component	extracellular space Inferred from electronic annotation. Source: Compara
Molecular_function	chemoattractant activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAM46926.1

Sequences

	Sequence		Length	Mass (Da)
	Q8NFI9 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 4EA43515F758327A	FASTA	170	19,195
	10 20 30 40 50 60 ALGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV 70 80 90 100 110 120 SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE 130 140 150 160 170 NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

References

[1]	"Fibroblast growth factor-10 is a mitogen for urothelial cells." Bagai S., Rubio E., Cheng J.F., Sweet R., Thomas R., Fuchs E., Grady R., Mitchell M., Bassuk J.A. J. Biol. Chem. 277:23828-23837(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Bladder EMBL AAM46926.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF508782 mRNA. Translation: AAM46926.1.
IPI	IPI00007307.
UniGene	Hs.664499.
3D structure databases
HSSP	HSSP built from PDB template 1NUN based on UniProtKB O15520.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8NFI9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG007580.
Gene expression databases
ArrayExpress	Q8NFI9.
Bgee	Q8NFI9.
Family and domain databases
InterPro	IPR008996. Cytokine_IL1-like. IPR002209. GF_heparin-bd. IPR002348. IL1_HBGF. [Graphical view]
PANTHER	PTHR11486. PTHR11486. 1 hit.
Pfam	PF00167. FGF. 1 hit. [Graphical view]
PRINTS	PR00263. HBGFFGF. PR00262. IL1HBGF.
SMART	SM00442. FGF. 1 hit. [Graphical view]
SUPFAM	SSF50353. Cytok_IL1_like. 1 hit.
PROSITE	PS00247. HBGF_FGF. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8NFI9_HUMAN

Accession

Primary (citable) accession number: Q8NFI9

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.