Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8NFI9

- Q8NFI9_HUMAN

UniProt

Q8NFI9 - Q8NFI9_HUMAN

Protein

Fibroblast growth factor

Gene

FGF10

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. chemoattractant activity Source: Ensembl

    GO - Biological processi

    1. angiogenesis Source: Ensembl
    2. blood vessel remodeling Source: Ensembl
    3. branch elongation involved in salivary gland morphogenesis Source: Ensembl
    4. bronchiole morphogenesis Source: Ensembl
    5. determination of left/right symmetry Source: Ensembl
    6. embryonic camera-type eye development Source: Ensembl
    7. embryonic digestive tract morphogenesis Source: Ensembl
    8. embryonic genitalia morphogenesis Source: Ensembl
    9. embryonic pattern specification Source: Ensembl
    10. epithelial cell migration Source: Ensembl
    11. epithelial cell proliferation involved in salivary gland morphogenesis Source: Ensembl
    12. epithelial tube branching involved in lung morphogenesis Source: Ensembl
    13. female genitalia morphogenesis Source: Ensembl
    14. fibroblast growth factor receptor signaling pathway involved in mammary gland specification Source: Ensembl
    15. hair follicle morphogenesis Source: Ensembl
    16. Harderian gland development Source: Ensembl
    17. induction of positive chemotaxis Source: Ensembl
    18. keratinocyte proliferation Source: Ensembl
    19. lacrimal gland development Source: Ensembl
    20. limb bud formation Source: Ensembl
    21. lung alveolus development Source: Ensembl
    22. lung proximal/distal axis specification Source: Ensembl
    23. male genitalia morphogenesis Source: Ensembl
    24. mammary gland bud formation Source: Ensembl
    25. mesenchymal cell differentiation involved in lung development Source: Ensembl
    26. mesenchymal-epithelial cell signaling involved in lung development Source: Ensembl
    27. metanephros morphogenesis Source: Ensembl
    28. muscle cell fate commitment Source: Ensembl
    29. negative regulation of cell proliferation Source: Ensembl
    30. negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
    31. odontogenesis of dentin-containing tooth Source: Ensembl
    32. organ growth Source: Ensembl
    33. organ induction Source: Ensembl
    34. otic vesicle formation Source: Ensembl
    35. pancreas development Source: Ensembl
    36. pituitary gland development Source: Ensembl
    37. positive regulation of canonical Wnt signaling pathway Source: Ensembl
    38. positive regulation of epithelial cell migration Source: Ensembl
    39. positive regulation of epithelial cell proliferation Source: Ensembl
    40. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
    41. positive regulation of fibroblast proliferation Source: Ensembl
    42. positive regulation of mitotic cell cycle Source: Ensembl
    43. positive regulation of Notch signaling pathway Source: Ensembl
    44. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    45. positive regulation of vascular endothelial growth factor receptor signaling pathway Source: Ensembl
    46. positive regulation of white fat cell proliferation Source: Ensembl
    47. radial glial cell differentiation Source: Ensembl
    48. regulation of activin receptor signaling pathway Source: Ensembl
    49. regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling Source: Ensembl
    50. regulation of prostatic bud formation Source: Ensembl
    51. regulation of smoothened signaling pathway Source: Ensembl
    52. response to estradiol Source: Ensembl
    53. response to lipopolysaccharide Source: Ensembl
    54. semicircular canal fusion Source: Ensembl
    55. smooth muscle cell differentiation Source: Ensembl
    56. somatic stem cell maintenance Source: Ensembl
    57. spleen development Source: Ensembl
    58. submandibular salivary gland formation Source: Ensembl
    59. thyroid gland development Source: Ensembl
    60. tissue regeneration Source: Ensembl
    61. Type II pneumocyte differentiation Source: Ensembl
    62. white fat cell differentiation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fibroblast growth factorUniRule annotation
    Short name:
    FGFUniRule annotation
    Gene namesi
    Name:FGF10Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ8NFI9.
    BgeeiQ8NFI9.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the heparin-binding growth factors family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG007580.

    Family and domain databases

    InterProiIPR008996. Cytokine_IL1-like.
    IPR028252. FGF10.
    IPR002209. Fibroblast_GF_fam.
    IPR028142. IL-1_fam/FGF_fam.
    [Graphical view]
    PANTHERiPTHR11486. PTHR11486. 1 hit.
    PTHR11486:SF21. PTHR11486:SF21. 1 hit.
    PfamiPF00167. FGF. 1 hit.
    [Graphical view]
    PRINTSiPR00263. HBGFFGF.
    PR00262. IL1HBGF.
    SMARTiSM00442. FGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF50353. SSF50353. 1 hit.
    PROSITEiPS00247. HBGF_FGF. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8NFI9-1 [UniParc]FASTAAdd to Basket

    « Hide

    ALGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY    50
    FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG 100
    KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR 150
    GQKTRRKNTS AHFLPMVVHS 170
    Length:170
    Mass (Da):19,195
    Last modified:October 1, 2002 - v1
    Checksum:i4EA43515F758327A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF508782 mRNA. Translation: AAM46926.1.
    UniGeneiHs.664499.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF508782 mRNA. Translation: AAM46926.1 .
    UniGenei Hs.664499.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG007580.

    Gene expression databases

    ArrayExpressi Q8NFI9.
    Bgeei Q8NFI9.

    Family and domain databases

    InterProi IPR008996. Cytokine_IL1-like.
    IPR028252. FGF10.
    IPR002209. Fibroblast_GF_fam.
    IPR028142. IL-1_fam/FGF_fam.
    [Graphical view ]
    PANTHERi PTHR11486. PTHR11486. 1 hit.
    PTHR11486:SF21. PTHR11486:SF21. 1 hit.
    Pfami PF00167. FGF. 1 hit.
    [Graphical view ]
    PRINTSi PR00263. HBGFFGF.
    PR00262. IL1HBGF.
    SMARTi SM00442. FGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50353. SSF50353. 1 hit.
    PROSITEi PS00247. HBGF_FGF. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BladderImported.

    Entry informationi

    Entry nameiQ8NFI9_HUMAN
    AccessioniPrimary (citable) accession number: Q8NFI9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.