##gff-version 3
Q8NFD2	UniProtKB	Chain	1	765	.	.	.	ID=PRO_0000085620;Note=Ankyrin repeat and protein kinase domain-containing protein 1	
Q8NFD2	UniProtKB	Domain	22	289	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q8NFD2	UniProtKB	Repeat	361	390	.	.	.	Note=ANK 1	
Q8NFD2	UniProtKB	Repeat	394	423	.	.	.	Note=ANK 2	
Q8NFD2	UniProtKB	Repeat	427	456	.	.	.	Note=ANK 3	
Q8NFD2	UniProtKB	Repeat	460	489	.	.	.	Note=ANK 4	
Q8NFD2	UniProtKB	Repeat	493	522	.	.	.	Note=ANK 5	
Q8NFD2	UniProtKB	Repeat	526	555	.	.	.	Note=ANK 6	
Q8NFD2	UniProtKB	Repeat	559	588	.	.	.	Note=ANK 7	
Q8NFD2	UniProtKB	Repeat	592	621	.	.	.	Note=ANK 8	
Q8NFD2	UniProtKB	Repeat	625	654	.	.	.	Note=ANK 9	
Q8NFD2	UniProtKB	Repeat	658	687	.	.	.	Note=ANK 10	
Q8NFD2	UniProtKB	Repeat	691	720	.	.	.	Note=ANK 11	
Q8NFD2	UniProtKB	Repeat	724	753	.	.	.	Note=ANK 12	
Q8NFD2	UniProtKB	Active site	145	145	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
Q8NFD2	UniProtKB	Binding site	28	36	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q8NFD2	UniProtKB	Binding site	51	51	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q8NFD2	UniProtKB	Natural variant	4	4	.	.	.	ID=VAR_040359;Note=D->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs35657708,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	122	122	.	.	.	ID=VAR_040360;Note=R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs35877321,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	239	239	.	.	.	ID=VAR_036784;Note=A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs7118900,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	276	276	.	.	.	ID=VAR_040361;Note=P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs35488601,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	318	318	.	.	.	ID=VAR_036785;Note=G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs11604671,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	347	347	.	.	.	ID=VAR_040362;Note=In a breast infiltrating ductal carcinoma sample%3B somatic mutation. K->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	366	366	.	.	.	ID=VAR_040363;Note=L->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs56339158,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	367	367	.	.	.	ID=VAR_040364;Note=H->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs34298987,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	376	376	.	.	.	ID=VAR_040365;Note=E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs56299709,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	426	426	.	.	.	ID=VAR_040366;Note=E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55699907,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	442	442	.	.	.	ID=VAR_036786;Note=G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs4938016,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	451	451	.	.	.	ID=VAR_040367;Note=G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs34983219,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	490	490	.	.	.	ID=VAR_036787;Note=H->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs2734849,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	595	595	.	.	.	ID=VAR_040368;Note=T->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55787008,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	596	596	.	.	.	ID=VAR_040369;Note=P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs7104979,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	653	653	.	.	.	ID=VAR_040370;Note=N->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55849504,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	670	670	.	.	.	ID=VAR_040371;Note=S->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs56006094,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	713	713	.	.	.	ID=VAR_025010;Note=E->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:14741327,ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs1800497,PMID:14741327,PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	717	717	.	.	.	ID=VAR_040372;Note=In a lung large cell carcinoma sample%3B somatic mutation. Q->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	736	736	.	.	.	ID=VAR_040373;Note=In a lung squamous cell carcinoma sample%3B somatic mutation. R->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=PMID:17344846	
Q8NFD2	UniProtKB	Natural variant	764	764	.	.	.	ID=VAR_040374;Note=In a lung neuroendocrine carcinoma sample%3B somatic mutation. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=PMID:17344846