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Q8NFA0

- UBP32_HUMAN

UniProt

Q8NFA0 - UBP32_HUMAN

Protein

Ubiquitin carboxyl-terminal hydrolase 32

Gene

USP32

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 117 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei743 – 7431NucleophilePROSITE-ProRule annotation
    Active sitei1526 – 15261Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Calcium bindingi241 – 252121PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi277 – 288122PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. ubiquitin-specific protease activity Source: InterPro
    3. ubiquitin thiolesterase activity Source: UniProtKB

    GO - Biological processi

    1. protein deubiquitination Source: UniProtKB
    2. ubiquitin-dependent protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Keywords - Biological processi

    Ubl conjugation pathway

    Keywords - Ligandi

    Calcium, Metal-binding

    Protein family/group databases

    MEROPSiC19.044.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin carboxyl-terminal hydrolase 32 (EC:3.4.19.12)
    Alternative name(s):
    Deubiquitinating enzyme 32
    Renal carcinoma antigen NY-REN-60
    Ubiquitin thioesterase 32
    Ubiquitin-specific-processing protease 32
    Gene namesi
    Name:USP32
    Synonyms:USP10
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:19143. USP32.

    Subcellular locationi

    Membrane Curated; Lipid-anchor Curated. Golgi apparatus 1 Publication

    GO - Cellular componenti

    1. Golgi apparatus Source: UniProtKB
    2. membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134982542.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 16011601Ubiquitin carboxyl-terminal hydrolase 32PRO_0000080663Add
    BLAST
    Propeptidei1602 – 16043Removed in mature formSequence AnalysisPRO_0000396658

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1173 – 11731Phosphotyrosine1 Publication
    Modified residuei1372 – 13721Phosphoserine2 Publications
    Modified residuei1601 – 16011Cysteine methyl esterSequence Analysis
    Lipidationi1601 – 16011S-farnesyl cysteineSequence Analysis

    Keywords - PTMi

    Lipoprotein, Methylation, Phosphoprotein, Prenylation

    Proteomic databases

    MaxQBiQ8NFA0.
    PaxDbiQ8NFA0.
    PRIDEiQ8NFA0.

    PTM databases

    PhosphoSiteiQ8NFA0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8NFA0.
    BgeeiQ8NFA0.
    CleanExiHS_USP10.
    HS_USP32.
    GenevestigatoriQ8NFA0.

    Organism-specific databases

    HPAiHPA044365.

    Interactioni

    Protein-protein interaction databases

    BioGridi124189. 26 interactions.
    IntActiQ8NFA0. 19 interactions.
    MINTiMINT-6779170.
    STRINGi9606.ENSP00000300896.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NFA0.
    SMRiQ8NFA0. Positions 15-49, 179-340, 730-915, 1233-1312, 1509-1565.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini91 – 12636EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini228 – 26336EF-hand 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini264 – 29936EF-hand 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini369 – 585217DUSPPROSITE-ProRule annotationAdd
    BLAST
    Domaini734 – 1567834USPAdd
    BLAST

    Sequence similaritiesi

    Belongs to the peptidase C19 family.Curated
    Contains 1 DUSP domain.PROSITE-ProRule annotation
    Contains 3 EF-hand domains.PROSITE-ProRule annotation
    Contains 1 USP domain.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG5210.
    HOGENOMiHOG000007511.
    HOVERGENiHBG057958.
    InParanoidiQ8NFA0.
    KOiK11837.
    OMAiSDNNNQC.
    OrthoDBiEOG7PP55V.
    PhylomeDBiQ8NFA0.
    TreeFamiTF324190.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    3.30.2230.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR006615. Pept_C19_DUSP.
    IPR018200. Pept_C19ubi-hydrolase_C_CS.
    IPR001394. Peptidase_C19_UCH.
    IPR028135. Ub_USP-typ.
    IPR028889. UCH/PAN2.
    [Graphical view]
    PfamiPF06337. DUSP. 1 hit.
    PF13202. EF-hand_5. 2 hits.
    PF14836. Ubiquitin_3. 1 hit.
    PF00443. UCH. 1 hit.
    [Graphical view]
    SMARTiSM00695. DUSP. 1 hit.
    SM00054. EFh. 2 hits.
    [Graphical view]
    SUPFAMiSSF143791. SSF143791. 2 hits.
    PROSITEiPS51283. DUSP. 1 hit.
    PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 3 hits.
    PS00972. USP_1. 1 hit.
    PS00973. USP_2. 1 hit.
    PS50235. USP_3. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8NFA0-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTCGLSY YMGQHCFIRE     50
    VLGDGVPPKV AEVIYCSFGG TSKGLHFNNL IVGLVLLTRG KDEEKAKYIF 100
    SLFSSESGNY VIREEMERML HVVDGKVPDT LRKCFSEGEK VNYEKFRNWL 150
    FLNKDAFTFS RWLLSGGVYV TLTDDSDTPT FYQTLAGVTH LEESDIIDLE 200
    KRYWLLKAQS RTGRFDLETF GPLVSPPIRP SLSEGLFNAF DENRDNHIDF 250
    KEISCGLSAC CRGPLAERQK FCFKVFDVDR DGVLSRVELR DMVVALLEVW 300
    KDNRTDDIPE LHMDLSDIVE GILNAHDTTK MGHLTLEDYQ IWSVKNVLAN 350
    EFLNLLFQVC HIVLGLRPAT PEEEGQIIRG WLERESRYGL QAGHNWFIIS 400
    MQWWQQWKEY VKYDANPVVI EPSSVLNGGK YSFGTAAHPM EQVEDRIGSS 450
    LSYVNTTEEK FSDNISTASE ASETAGSGFL YSATPGADVC FARQHNTSDN 500
    NNQCLLGANG NILLHLNPQK PGAIDNQPLV TQEPVKATSL TLEGGRLKRT 550
    PQLIHGRDYE MVPEPVWRAL YHWYGANLAL PRPVIKNSKT DIPELELFPR 600
    YLLFLRQQPA TRTQQSNIWV NMGNVPSPNA PLKRVLAYTG CFSRMQTIKE 650
    IHEYLSQRLR IKEEDMRLWL YNSENYLTLL DDEDHKLEYL KIQDEQHLVI 700
    EVRNKDMSWP EEMSFIANSS KIDRHKVPTE KGATGLSNLG NTCFMNSSIQ 750
    CVSNTQPLTQ YFISGRHLYE LNRTNPIGMK GHMAKCYGDL VQELWSGTQK 800
    NVAPLKLRWT IAKYAPRFNG FQQQDSQELL AFLLDGLHED LNRVHEKPYV 850
    ELKDSDGRPD WEVAAEAWDN HLRRNRSIVV DLFHGQLRSQ VKCKTCGHIS 900
    VRFDPFNFLS LPLPMDSYMH LEITVIKLDG TTPVRYGLRL NMDEKYTGLK 950
    KQLSDLCGLN SEQILLAEVH GSNIKNFPQD NQKVRLSVSG FLCAFEIPVP 1000
    VSPISASSPT QTDFSSSPST NEMFTLTTNG DLPRPIFIPN GMPNTVVPCG 1050
    TEKNFTNGMV NGHMPSLPDS PFTGYIIAVH RKMMRTELYF LSSQKNRPSL 1100
    FGMPLIVPCT VHTRKKDLYD AVWIQVSRLA SPLPPQEASN HAQDCDDSMG 1150
    YQYPFTLRVV QKDGNSCAWC PWYRFCRGCK IDCGEDRAFI GNAYIAVDWD 1200
    PTALHLRYQT SQERVVDEHE SVEQSRRAQA EPINLDSCLR AFTSEEELGE 1250
    NEMYYCSKCK THCLATKKLD LWRLPPILII HLKRFQFVNG RWIKSQKIVK 1300
    FPRESFDPSA FLVPRDPALC QHKPLTPQGD ELSEPRILAR EVKKVDAQSS 1350
    AGEEDVLLSK SPSSLSANII SSPKGSPSSS RKSGTSCPSS KNSSPNSSPR 1400
    TLGRSKGRLR LPQIGSKNKL SSSKENLDAS KENGAGQICE LADALSRGHV 1450
    LGGSQPELVT PQDHEVALAN GFLYEHEACG NGYSNGQLGN HSEEDSTDDQ 1500
    REDTRIKPIY NLYAISCHSG ILGGGHYVTY AKNPNCKWYC YNDSSCKELH 1550
    PDEIDTDSAY ILFYEQQGID YAQFLPKTDG KKMADTSSMD EDFESDYKKY 1600
    CVLQ 1604
    Length:1,604
    Mass (Da):181,656
    Last modified:October 1, 2002 - v1
    Checksum:iA621F764B76321E3
    GO
    Isoform 2 (identifier: Q8NFA0-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         380-390: GWLERESRYGL → TLETDQIYTRN
         391-1604: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:390
    Mass (Da):44,703
    Checksum:i45F2BC9CFE8CECB4
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti884 – 8841H → R in AAK30207. 1 PublicationCurated
    Sequence conflicti1167 – 11671C → S in AAK30207. 1 PublicationCurated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti76 – 761H → Y.
    Corresponds to variant rs7208980 [ dbSNP | Ensembl ].
    VAR_051536
    Natural varianti1469 – 14691A → G.
    Corresponds to variant rs3207630 [ dbSNP | Ensembl ].
    VAR_051537
    Natural varianti1568 – 15681G → R.
    Corresponds to variant rs16944142 [ dbSNP | Ensembl ].
    VAR_051538
    Natural varianti1578 – 15781T → I.
    Corresponds to variant rs16944136 [ dbSNP | Ensembl ].
    VAR_051539

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei380 – 39011GWLERESRYGL → TLETDQIYTRN in isoform 2. 1 PublicationVSP_056307Add
    BLAST
    Alternative sequencei391 – 16041214Missing in isoform 2. 1 PublicationVSP_056308Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF533230 mRNA. Translation: AAM97922.1.
    AF350251 mRNA. Translation: AAK30207.1.
    AC003962 Genomic DNA. No translation available.
    AC025048 Genomic DNA. No translation available.
    AC037475 Genomic DNA. No translation available.
    AC104763 Genomic DNA. No translation available.
    BC054344 mRNA. Translation: AAH54344.1.
    AF155116 mRNA. Translation: AAD42882.1.
    CCDSiCCDS32697.1.
    RefSeqiNP_115971.2. NM_032582.3.
    UniGeneiHs.132868.

    Genome annotation databases

    EnsembliENST00000300896; ENSP00000300896; ENSG00000170832.
    ENST00000393003; ENSP00000376727; ENSG00000170832.
    GeneIDi84669.
    KEGGihsa:84669.
    UCSCiuc002iyn.1. human.

    Polymorphism databases

    DMDMi47606649.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF533230 mRNA. Translation: AAM97922.1 .
    AF350251 mRNA. Translation: AAK30207.1 .
    AC003962 Genomic DNA. No translation available.
    AC025048 Genomic DNA. No translation available.
    AC037475 Genomic DNA. No translation available.
    AC104763 Genomic DNA. No translation available.
    BC054344 mRNA. Translation: AAH54344.1 .
    AF155116 mRNA. Translation: AAD42882.1 .
    CCDSi CCDS32697.1.
    RefSeqi NP_115971.2. NM_032582.3.
    UniGenei Hs.132868.

    3D structure databases

    ProteinModelPortali Q8NFA0.
    SMRi Q8NFA0. Positions 15-49, 179-340, 730-915, 1233-1312, 1509-1565.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 124189. 26 interactions.
    IntActi Q8NFA0. 19 interactions.
    MINTi MINT-6779170.
    STRINGi 9606.ENSP00000300896.

    Protein family/group databases

    MEROPSi C19.044.

    PTM databases

    PhosphoSitei Q8NFA0.

    Polymorphism databases

    DMDMi 47606649.

    Proteomic databases

    MaxQBi Q8NFA0.
    PaxDbi Q8NFA0.
    PRIDEi Q8NFA0.

    Protocols and materials databases

    DNASUi 84669.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000300896 ; ENSP00000300896 ; ENSG00000170832 .
    ENST00000393003 ; ENSP00000376727 ; ENSG00000170832 .
    GeneIDi 84669.
    KEGGi hsa:84669.
    UCSCi uc002iyn.1. human.

    Organism-specific databases

    CTDi 84669.
    GeneCardsi GC17M058254.
    HGNCi HGNC:19143. USP32.
    HPAi HPA044365.
    MIMi 607740. gene.
    neXtProti NX_Q8NFA0.
    PharmGKBi PA134982542.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5210.
    HOGENOMi HOG000007511.
    HOVERGENi HBG057958.
    InParanoidi Q8NFA0.
    KOi K11837.
    OMAi SDNNNQC.
    OrthoDBi EOG7PP55V.
    PhylomeDBi Q8NFA0.
    TreeFami TF324190.

    Miscellaneous databases

    ChiTaRSi USP32. human.
    GenomeRNAii 84669.
    NextBioi 74669.
    PROi Q8NFA0.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8NFA0.
    Bgeei Q8NFA0.
    CleanExi HS_USP10.
    HS_USP32.
    Genevestigatori Q8NFA0.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    3.30.2230.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR006615. Pept_C19_DUSP.
    IPR018200. Pept_C19ubi-hydrolase_C_CS.
    IPR001394. Peptidase_C19_UCH.
    IPR028135. Ub_USP-typ.
    IPR028889. UCH/PAN2.
    [Graphical view ]
    Pfami PF06337. DUSP. 1 hit.
    PF13202. EF-hand_5. 2 hits.
    PF14836. Ubiquitin_3. 1 hit.
    PF00443. UCH. 1 hit.
    [Graphical view ]
    SMARTi SM00695. DUSP. 1 hit.
    SM00054. EFh. 2 hits.
    [Graphical view ]
    SUPFAMi SSF143791. SSF143791. 2 hits.
    PROSITEi PS51283. DUSP. 1 hit.
    PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 3 hits.
    PS00972. USP_1. 1 hit.
    PS00973. USP_2. 1 hit.
    PS50235. USP_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Brain.
    2. "Identification of a novel ubiquitin specific protease gene related to testes development from human testes cDNA library."
      Sha J.H.
      Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 331-1604 (ISOFORM 1).
      Tissue: Testis.
    3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Uterus.
    5. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 536-1363 (ISOFORM 1), IDENTIFICATION AS A RENAL CANCER ANTIGEN.
    6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    7. "Towards complete sets of farnesylated and geranylgeranylated proteins."
      Maurer-Stroh S., Koranda M., Benetka W., Schneider G., Sirota F.L., Eisenhaber F.
      PLoS Comput. Biol. 3:634-648(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: ISOPRENYLATION AT CYS-1601.
    8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1173, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1372, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    10. "USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers."
      Akhavantabasi S., Akman H.B., Sapmaz A., Keller J., Petty E.M., Erson A.E.
      Mamm. Genome 21:388-397(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: CATALYTIC ACTIVITY, SUBCELLULAR LOCATION.
    11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1372, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiUBP32_HUMAN
    AccessioniPrimary (citable) accession number: Q8NFA0
    Secondary accession number(s): Q7Z5T3, Q9BX85, Q9Y591
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 117 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. Peptidase families
      Classification of peptidase families and list of entries
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3