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Protein
Submitted name:

Hepatocellular carcinoma-associated antigen

Gene

HCA107

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocellular carcinoma-associated antigenImported
Gene namesi
Name:HCA107Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ8NEY2.
PeptideAtlasiQ8NEY2.

Expressioni

Gene expression databases

BgeeiENSG00000170684.

Structurei

3D structure databases

ProteinModelPortaliQ8NEY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 51C2H2-typeInterPro annotationAdd BLAST24
Domaini102 – 129C2H2-typeInterPro annotationAdd BLAST28
Domaini130 – 157C2H2-typeInterPro annotationAdd BLAST28
Domaini257 – 284C2H2-typeInterPro annotationAdd BLAST28
Domaini285 – 307C2H2-typeInterPro annotationAdd BLAST23
Domaini316 – 339C2H2-typeInterPro annotationAdd BLAST24

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG071356.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF57667. SSF57667. 2 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequencei

Sequence statusi: Complete.

Q8NEY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDHKKLGCQL FRGPSRGQGS EREELKALSC LRCGKQFTVA WKLLRHAQWD
60 70 80 90 100
HGLSIYQTES EAPEAPLLGL AEVAAAVSAV VGPAAEAKSP RASGSGLTRR
110 120 130 140 150
SPTCPVCKKT LSSFSNLKVH MRSHTGERPY ACDQCPYACA QSSKLNRHKK
160 170 180 190 200
THRQVPPQSP LMADTSQEQA SAAPPEPAVH AAAPTSTLPC SGGEGAGAAA
210 220 230 240 250
TAGVQEPGAP GSGAQAGPGG DTWGAITTEQ RTDPANSQKA SPKKMPKSGG
260 270 280 290 300
KSRGPGGSCE FCGKHFTNSS NLTVHRRSHT GERPYTCEFC NYACAQSSKL
310 320 330 340
NRHRRMHGMT PGSTRFECPH CHVPFGLRAT LDKHLRQKHP EAAGEA
Length:346
Mass (Da):36,732
Last modified:October 1, 2002 - v1
Checksum:iC1CB8235F8E4182B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY040679 mRNA. Translation: AAK84667.1.
UniGeneiHs.192237.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ8NEY2_HUMAN
AccessioniPrimary (citable) accession number: Q8NEY2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 5, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.