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Protein

Protein WFDC9

Gene

WFDC9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Although this protein was isolated in a region containing several WAP proteins and was defined as a WAP protein, it does not contain a classical WAP domain.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WFDC9
Gene namesi
Name:WFDC9
Synonyms:WAP9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000180205.3
HGNCiHGNC:20380 WFDC9
neXtProtiNX_Q8NEX5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134934414

Polymorphism and mutation databases

BioMutaiWFDC9
DMDMi26401304

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000004138524 – 89Protein WFDC9Add BLAST66

Proteomic databases

PaxDbiQ8NEX5
PeptideAtlasiQ8NEX5
PRIDEiQ8NEX5
ProteomicsDBi73227

PTM databases

iPTMnetiQ8NEX5
PhosphoSitePlusiQ8NEX5

Expressioni

Gene expression databases

BgeeiENSG00000180205
CleanExiHS_WFDC9
GenevisibleiQ8NEX5 HS

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
MEOX2P502223EBI-10270812,EBI-748397

Protein-protein interaction databases

BioGridi129232, 6 interactors
IntActiQ8NEX5, 1 interactor
STRINGi9606.ENSP00000320532

Structurei

3D structure databases

ProteinModelPortaliQ8NEX5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J3VS Eukaryota
ENOG4111C2G LUCA
GeneTreeiENSGT00840000129968
HOGENOMiHOG000231001
HOVERGENiHBG058740
InParanoidiQ8NEX5
OMAiIEQCWVQ
OrthoDBiEOG091G14M9
PhylomeDBiQ8NEX5
TreeFamiTF338513

Family and domain databases

InterProiView protein in InterPro
IPR029725 WFDC9
IPR020310 WFDC9/WFDC11
PANTHERiPTHR19441:SF16 PTHR19441:SF16, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD288743 WFDC9_WDFC11, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8NEX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPWILLLVM FISGVVMLLP VLGSFWNKDP FLDMIRETEQ CWVQPPYKYC
60 70 80
EKRCTKIMTC VRPNHTCCWT YCGNICLDNE EPLKSMLNP
Length:89
Mass (Da):10,506
Last modified:October 1, 2002 - v1
Checksum:i9CC9B2013FA679EB
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02191127N → T. Corresponds to variant dbSNP:rs2245898Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY047610 mRNA Translation: AAK97772.1
AL031671 Genomic DNA No translation available.
BC069295 mRNA Translation: AAH69295.1
BC101652 mRNA Translation: AAI01653.1
BC101656 mRNA Translation: AAI01657.1
CCDSiCCDS13362.1
RefSeqiNP_671731.1, NM_147198.3
UniGeneiHs.249828

Genome annotation databases

EnsembliENST00000326000; ENSP00000320532; ENSG00000180205
GeneIDi259240
KEGGihsa:259240
UCSCiuc002xoy.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiWFDC9_HUMAN
AccessioniPrimary (citable) accession number: Q8NEX5
Secondary accession number(s): Q3MIX6, Q5TGZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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