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Protein

Uncharacterized protein C1orf64

Gene

C1orf64

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf64
Gene namesi
Name:C1orf64
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:28339. C1orf64.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672514.

Polymorphism and mutation databases

BioMutaiC1orf64.
DMDMi74751258.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 169169Uncharacterized protein C1orf64PRO_0000247124Add
BLAST

Proteomic databases

PaxDbiQ8NEQ6.
PRIDEiQ8NEQ6.

PTM databases

iPTMnetiQ8NEQ6.
PhosphoSiteiQ8NEQ6.

Expressioni

Gene expression databases

BgeeiQ8NEQ6.
CleanExiHS_C1orf64.
GenevisibleiQ8NEQ6. HS.

Organism-specific databases

HPAiHPA026676.

Interactioni

Protein-protein interaction databases

BioGridi127222. 2 interactions.
STRINGi9606.ENSP00000332162.

Structurei

3D structure databases

ProteinModelPortaliQ8NEQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J0N6. Eukaryota.
ENOG41114KN. LUCA.
GeneTreeiENSGT00390000000265.
HOGENOMiHOG000065780.
HOVERGENiHBG080949.
InParanoidiQ8NEQ6.
OMAiIVFCGEN.
OrthoDBiEOG73V6MK.
PhylomeDBiQ8NEQ6.
TreeFamiTF338217.

Family and domain databases

InterProiIPR027852. DUF4654.
[Graphical view]
PfamiPF15547. DUF4654. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NEQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSEDPRDW RANLKGTIRE TGLETSSGGK LAGHQKTVPT AHLTFVIDCT
60 70 80 90 100
HGKQLSLAAT ASPPQAPSPN RGLVTPPMKT YIVFCGENWP HLTRVTPMGG
110 120 130 140 150
GCLAQARATL PLCRGSVASA SFPVSPLCPQ EVPEAKGKPV KAAPVRSSTW
160
GTVKDSLKAL SSCVCGQAD
Length:169
Mass (Da):17,657
Last modified:October 1, 2002 - v1
Checksum:i53902A504A22451D
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti52 – 521G → W in a breast cancer sample; somatic mutation. 1 Publication
VAR_035491
Natural varianti100 – 1001G → W in a breast cancer sample; somatic mutation. 1 Publication
VAR_035492
Natural varianti112 – 1121L → F.
Corresponds to variant rs34950166 [ dbSNP | Ensembl ].
VAR_033654

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127425 mRNA. Translation: BAG54501.1.
AL355994 Genomic DNA. Translation: CAI16132.1.
CH471167 Genomic DNA. Translation: EAW51759.1.
BC017946 mRNA. Translation: AAH17946.1.
CCDSiCCDS166.1.
RefSeqiNP_849162.1. NM_178840.3.
UniGeneiHs.29190.

Genome annotation databases

EnsembliENST00000329454; ENSP00000332162; ENSG00000183888.
GeneIDi149563.
KEGGihsa:149563.
UCSCiuc001axn.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127425 mRNA. Translation: BAG54501.1.
AL355994 Genomic DNA. Translation: CAI16132.1.
CH471167 Genomic DNA. Translation: EAW51759.1.
BC017946 mRNA. Translation: AAH17946.1.
CCDSiCCDS166.1.
RefSeqiNP_849162.1. NM_178840.3.
UniGeneiHs.29190.

3D structure databases

ProteinModelPortaliQ8NEQ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127222. 2 interactions.
STRINGi9606.ENSP00000332162.

PTM databases

iPTMnetiQ8NEQ6.
PhosphoSiteiQ8NEQ6.

Polymorphism and mutation databases

BioMutaiC1orf64.
DMDMi74751258.

Proteomic databases

PaxDbiQ8NEQ6.
PRIDEiQ8NEQ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329454; ENSP00000332162; ENSG00000183888.
GeneIDi149563.
KEGGihsa:149563.
UCSCiuc001axn.4. human.

Organism-specific databases

CTDi149563.
GeneCardsiC1orf64.
H-InvDBHIX0023601.
HGNCiHGNC:28339. C1orf64.
HPAiHPA026676.
neXtProtiNX_Q8NEQ6.
PharmGKBiPA142672514.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J0N6. Eukaryota.
ENOG41114KN. LUCA.
GeneTreeiENSGT00390000000265.
HOGENOMiHOG000065780.
HOVERGENiHBG080949.
InParanoidiQ8NEQ6.
OMAiIVFCGEN.
OrthoDBiEOG73V6MK.
PhylomeDBiQ8NEQ6.
TreeFamiTF338217.

Miscellaneous databases

GenomeRNAii149563.
PROiQ8NEQ6.

Gene expression databases

BgeeiQ8NEQ6.
CleanExiHS_C1orf64.
GenevisibleiQ8NEQ6. HS.

Family and domain databases

InterProiIPR027852. DUF4654.
[Graphical view]
PfamiPF15547. DUF4654. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thalamus.
  2. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.
  5. Cited for: VARIANTS [LARGE SCALE ANALYSIS] TRP-52 AND TRP-100.

Entry informationi

Entry nameiCA064_HUMAN
AccessioniPrimary (citable) accession number: Q8NEQ6
Secondary accession number(s): B3KXI9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.