Q8NEL9 (DDHD1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phospholipase DDHD1
EC=3.1.1.-

Alternative name(s):
DDHD domain-containing protein 1
Phosphatidic acid-preferring phospholipase A1 homolog
Short name=PA-PLA1

Gene names

Name:	DDHD1
Synonyms:	KIAA1705

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	900 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity. Ref.9
Subunit structure	Forms homooligomers and, to a much smaller extent, heterooligomers with DDHD2. Ref.9
Subcellular location	Cytoplasm Ref.7.
Tissue specificity	Highly expressed in testis. Also expressed in brain, spleen and lung. Only expressed in cerebellum in fetal brain. Ref.6
Sequence similarities	Belongs to the PA-PLA1 family. Contains 1 DDHD domain.
Sequence caution	The sequence BAB21796.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. The sequence BAB71679.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Biological process	Lipid degradation Lipid metabolism
Cellular component	Cytoplasm
Coding sequence diversity	Alternative splicing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	lipid catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8NEL9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8NEL9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

Isoform 3 (identifier: Q8NEL9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-418: Missing.
     813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

Note: No experimental confirmation available.

Isoform 4 (identifier: Q8NEL9-4)

The sequence of this isoform differs from the canonical sequence as follows:
     337-337: D → DGSGINYS
     813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 900	900	Phospholipase DDHD1		PRO_0000079845
Regions
	Domain	611 – 886	276	DDHD
Sites
	Active site	537	1	By similarity
Natural variations
	Alternative sequence	1 – 418	418	Missing in isoform 3.		VSP_008628
	Alternative sequence	337	1	D → DGSGINYS in isoform 4.		VSP_045340
	Alternative sequence	813 – 841	29	YFRLQ…DNALV → L in isoform 2, isoform 3 and isoform 4.		VSP_008629
Experimental info
	Mutagenesis	590	1	L → S: No effect on homooligomer formation; when associated with S-593. Ref.9
	Mutagenesis	593	1	I → S: No effect on homooligomer formation; when associated with S-590. Ref.9
	Mutagenesis	662	1	D → A: Markedly decreased enzymatic activity. Ref.9
	Mutagenesis	848	1	D → A: Markedly decreased enzymatic activity. Ref.9
	Mutagenesis	867	1	H → A: Markedly decreased enzymatic activity. Ref.9
	Mutagenesis	875	1	D → A: No effect on enzymatic activity. Ref.9
	Sequence conflict	109	1	G → GGG in AK125372. Ref.2
	Sequence conflict	675	1	H → R in AAH30703. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 24, 2003. Version 2. Checksum: D70DAD1A73AC22B8	FASTA	900	100,435
	10 20 30 40 50 60 MNYPGRGSPR SPEHNGRGGG GGAWELGSDA RPAFGGGVCC FEHLPGGDPD DGDVPLALLR 70 80 90 100 110 120 GEPGLHLAPG TDDHNHHLAL DPCLSDENYD FSSAESGSSL RYYSEGESGG GGSSLSLHPP 130 140 150 160 170 180 QQPPLVPTNS GGGGATGGSP GERKRTRLGG PAARHRYEVV TELGPEEVRW FYKEDKKTWK 190 200 210 220 230 240 PFIGYDSLRI ELAFRTLLQT TGARPQGGDR DGDHVCSPTG PASSSGEDDD EDRACGFCQS 250 260 270 280 290 300 TTGHEPEMVE LVNIEPVCVR GGLYEVDVTQ GECYPVYWNQ ADKIPVMRGQ WFIDGTWQPL 310 320 330 340 350 360 EEEESNLIEQ EHLNCFRGQQ MQENFDIEVS KSIDGKDAVH SFKLSRNHVD WHSVDEVYLY 370 380 390 400 410 420 SDATTSKIAR TVTQKLGFSK ASSSGTRLHR GYVEEATLED KPSQTTHIVF VVHGIGQKMD 430 440 450 460 470 480 QGRIIKNTAM MREAARKIEE RHFSNHATHV EFLPVEWRSK LTLDGDTVDS ITPDKVRGLR 490 500 510 520 530 540 DMLNSSAMDI MYYTSPLYRD ELVKGLQQEL NRLYSLFCSR NPDFEEKGGK VSIVSHSLGC 550 560 570 580 590 600 VITYDIMTGW NPVRLYEQLL QKEEELPDER WMSYEERHLL DELYITKRRL KEIEERLHGL 610 620 630 640 650 660 KASSMTQTPA LKFKVENFFC MGSPLAVFLA LRGIRPGNTG SQDHILPREI CNRLLNIFHP 670 680 690 700 710 720 TDPVAYRLEP LILKHYSNIS PVQIHWYNTS NPLPYEHMKP SFLNPAKEPT SVSENEGIST 730 740 750 760 770 780 IPSPVTSPVL SRRHYGESIT NIGKASILGA ASIGKGLGGM LFSRFGRSST TQSSETSKDS 790 800 810 820 830 840 MEDEKKPVAS PSATTVGTQT LPHSSSGFLD SAYFRLQESF FNLPQLLFPE NVMQNKDNAL 850 860 870 880 890 900 VELDHRIDFE LREGLVESRY WSAVTSHTAY WSSLDVALFL LTFMYKHEHD DDAKPNLDPI
	Isoform 2 [UniParc]. Checksum: D58636E03DB8BF78	FASTA	872	97,050
	10 20 30 40 50 60 MNYPGRGSPR SPEHNGRGGG GGAWELGSDA RPAFGGGVCC FEHLPGGDPD DGDVPLALLR 70 80 90 100 110 120 GEPGLHLAPG TDDHNHHLAL DPCLSDENYD FSSAESGSSL RYYSEGESGG GGSSLSLHPP 130 140 150 160 170 180 QQPPLVPTNS GGGGATGGSP GERKRTRLGG PAARHRYEVV TELGPEEVRW FYKEDKKTWK 190 200 210 220 230 240 PFIGYDSLRI ELAFRTLLQT TGARPQGGDR DGDHVCSPTG PASSSGEDDD EDRACGFCQS 250 260 270 280 290 300 TTGHEPEMVE LVNIEPVCVR GGLYEVDVTQ GECYPVYWNQ ADKIPVMRGQ WFIDGTWQPL 310 320 330 340 350 360 EEEESNLIEQ EHLNCFRGQQ MQENFDIEVS KSIDGKDAVH SFKLSRNHVD WHSVDEVYLY 370 380 390 400 410 420 SDATTSKIAR TVTQKLGFSK ASSSGTRLHR GYVEEATLED KPSQTTHIVF VVHGIGQKMD 430 440 450 460 470 480 QGRIIKNTAM MREAARKIEE RHFSNHATHV EFLPVEWRSK LTLDGDTVDS ITPDKVRGLR 490 500 510 520 530 540 DMLNSSAMDI MYYTSPLYRD ELVKGLQQEL NRLYSLFCSR NPDFEEKGGK VSIVSHSLGC 550 560 570 580 590 600 VITYDIMTGW NPVRLYEQLL QKEEELPDER WMSYEERHLL DELYITKRRL KEIEERLHGL 610 620 630 640 650 660 KASSMTQTPA LKFKVENFFC MGSPLAVFLA LRGIRPGNTG SQDHILPREI CNRLLNIFHP 670 680 690 700 710 720 TDPVAYRLEP LILKHYSNIS PVQIHWYNTS NPLPYEHMKP SFLNPAKEPT SVSENEGIST 730 740 750 760 770 780 IPSPVTSPVL SRRHYGESIT NIGKASILGA ASIGKGLGGM LFSRFGRSST TQSSETSKDS 790 800 810 820 830 840 MEDEKKPVAS PSATTVGTQT LPHSSSGFLD SALELDHRID FELREGLVES RYWSAVTSHT 850 860 870 AYWSSLDVAL FLLTFMYKHE HDDDAKPNLD PI
	Isoform 3 [UniParc]. Checksum: 06138258AEADA349	FASTA	454	51,554
	10 20 30 40 50 60 MDQGRIIKNT AMMREAARKI EERHFSNHAT HVEFLPVEWR SKLTLDGDTV DSITPDKVRG 70 80 90 100 110 120 LRDMLNSSAM DIMYYTSPLY RDELVKGLQQ ELNRLYSLFC SRNPDFEEKG GKVSIVSHSL 130 140 150 160 170 180 GCVITYDIMT GWNPVRLYEQ LLQKEEELPD ERWMSYEERH LLDELYITKR RLKEIEERLH 190 200 210 220 230 240 GLKASSMTQT PALKFKVENF FCMGSPLAVF LALRGIRPGN TGSQDHILPR EICNRLLNIF 250 260 270 280 290 300 HPTDPVAYRL EPLILKHYSN ISPVQIHWYN TSNPLPYEHM KPSFLNPAKE PTSVSENEGI 310 320 330 340 350 360 STIPSPVTSP VLSRRHYGES ITNIGKASIL GAASIGKGLG GMLFSRFGRS STTQSSETSK 370 380 390 400 410 420 DSMEDEKKPV ASPSATTVGT QTLPHSSSGF LDSALELDHR IDFELREGLV ESRYWSAVTS 430 440 450 HTAYWSSLDV ALFLLTFMYK HEHDDDAKPN LDPI
	Isoform 4 [UniParc]. Checksum: 80B36E3D1CAE627F	FASTA	879	97,729
	10 20 30 40 50 60 MNYPGRGSPR SPEHNGRGGG GGAWELGSDA RPAFGGGVCC FEHLPGGDPD DGDVPLALLR 70 80 90 100 110 120 GEPGLHLAPG TDDHNHHLAL DPCLSDENYD FSSAESGSSL RYYSEGESGG GGSSLSLHPP 130 140 150 160 170 180 QQPPLVPTNS GGGGATGGSP GERKRTRLGG PAARHRYEVV TELGPEEVRW FYKEDKKTWK 190 200 210 220 230 240 PFIGYDSLRI ELAFRTLLQT TGARPQGGDR DGDHVCSPTG PASSSGEDDD EDRACGFCQS 250 260 270 280 290 300 TTGHEPEMVE LVNIEPVCVR GGLYEVDVTQ GECYPVYWNQ ADKIPVMRGQ WFIDGTWQPL 310 320 330 340 350 360 EEEESNLIEQ EHLNCFRGQQ MQENFDIEVS KSIDGKDGSG INYSAVHSFK LSRNHVDWHS 370 380 390 400 410 420 VDEVYLYSDA TTSKIARTVT QKLGFSKASS SGTRLHRGYV EEATLEDKPS QTTHIVFVVH 430 440 450 460 470 480 GIGQKMDQGR IIKNTAMMRE AARKIEERHF SNHATHVEFL PVEWRSKLTL DGDTVDSITP 490 500 510 520 530 540 DKVRGLRDML NSSAMDIMYY TSPLYRDELV KGLQQELNRL YSLFCSRNPD FEEKGGKVSI 550 560 570 580 590 600 VSHSLGCVIT YDIMTGWNPV RLYEQLLQKE EELPDERWMS YEERHLLDEL YITKRRLKEI 610 620 630 640 650 660 EERLHGLKAS SMTQTPALKF KVENFFCMGS PLAVFLALRG IRPGNTGSQD HILPREICNR 670 680 690 700 710 720 LLNIFHPTDP VAYRLEPLIL KHYSNISPVQ IHWYNTSNPL PYEHMKPSFL NPAKEPTSVS 730 740 750 760 770 780 ENEGISTIPS PVTSPVLSRR HYGESITNIG KASILGAASI GKGLGGMLFS RFGRSSTTQS 790 800 810 820 830 840 SETSKDSMED EKKPVASPSA TTVGTQTLPH SSSGFLDSAL ELDHRIDFEL REGLVESRYW 850 860 870 SAVTSHTAYW SSLDVALFLL TFMYKHEHDD DAKPNLDPI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O. DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Brain.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 357-900 (ISOFORMS 2/4). Tissue: Fetal brain and Testis.
[3]	"The DNA sequence and analysis of human chromosome 14." Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J. Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2). Tissue: Brain and Testis.
[6]	"Cloning of a phosphatidic acid-preferring phospholipase A1 from bovine testis." Higgs H.N., Han M.H., Johnson G.E., Glomset J.A. J. Biol. Chem. 273:5468-5477(1998) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[7]	"p125 is localized in endoplasmic reticulum exit sites and involved in their organization." Shimoi W., Ezawa I., Nakamoto K., Uesaki S., Gabreski G., Aridor M., Yamamoto A., Nagahama M., Tagaya M., Tani K. J. Biol. Chem. 280:10141-10148(2005) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION.
[8]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
[9]	"Roles of SAM and DDHD domains in mammalian intracellular phospholipase A1 KIAA0725p." Inoue H., Baba T., Sato S., Ohtsuki R., Takemori A., Watanabe T., Tagaya M., Tani K. Biochim. Biophys. Acta 1823:930-939(2012) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBUNIT, HOMOOLIGOMER FORMATION, INTERACTION WITH DDHD2, MUTAGENESIS OF LEU-590; ILE-593; ASP-662; ASP-848; HIS-867 AND ASP-875.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB051492 mRNA. Translation: BAB21796.1. Different initiation. AK058137 mRNA. Translation: BAB71679.1. Different initiation. AK125372 mRNA. No translation available. AL352979 Genomic DNA. No translation available. AL356020 Genomic DNA. No translation available. CH471061 Genomic DNA. Translation: EAW80623.1. BC018014 mRNA. Translation: AAH18014.1. BC030703 mRNA. Translation: AAH30703.1.
IPI	IPI00376941. IPI00794129. IPI00956137.
RefSeq	NP_001153619.1. NM_001160147.1. NP_001153620.1. NM_001160148.1. NP_085140.2. NM_030637.2.
UniGene	Hs.125525.
3D structure databases
ProteinModelPortal	Q8NEL9.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000350401.
PTM databases
PhosphoSite	Q8NEL9.
Polymorphism databases
DMDM	37999716.
Proteomic databases
PaxDb	Q8NEL9.
PRIDE	Q8NEL9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000323669; ENSP00000327104; ENSG00000100523. ENST00000357758; ENSP00000350401; ENSG00000100523. ENST00000395606; ENSP00000378970; ENSG00000100523.
GeneID	80821.
KEGG	hsa:80821.
UCSC	uc001xag.3. human. uc001xah.3. human. uc001xai.3. human.
Organism-specific databases
CTD	80821.
GeneCards	GC14M053510.
HGNC	HGNC:19714. DDHD1.
HPA	HPA049870.
MIM	614603. gene.
neXtProt	NX_Q8NEL9.
PharmGKB	PA134861440.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG285690.
HOGENOM	HOG000007412.
HOVERGEN	HBG059037.
InParanoid	Q8NEL9.
KO	K13619.
OMA	LDPCLSD.
PhylomeDB	Q8NEL9.
Gene expression databases
ArrayExpress	Q8NEL9.
Bgee	Q8NEL9.
CleanEx	HS_DDHD1.
Genevestigator	Q8NEL9.
GermOnline	ENSG00000100523. Homo sapiens.
Family and domain databases
InterPro	IPR004177. DDHD. [Graphical view]
Pfam	PF02862. DDHD. 1 hit. [Graphical view]
PROSITE	PS51043. DDHD. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	80821.
NextBio	71223.
SOURCE	Search...

Entry information

Entry name

DDHD1_HUMAN

Accession

Primary (citable) accession number: Q8NEL9
Secondary accession number(s): G5E9D1 , Q8WVH3, Q96LL2, Q9C0F8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 24, 2003
Last sequence update:	October 24, 2003
Last modified:	April 3, 2013
This is version 84 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.