Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8NEL9

- DDHD1_HUMAN

UniProt

Q8NEL9 - DDHD1_HUMAN

Protein

Phospholipase DDHD1

Gene

DDHD1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 2 (24 Oct 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity.1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei537 – 5371By similarity

    GO - Molecular functioni

    1. hydrolase activity Source: UniProtKB-KW
    2. metal ion binding Source: InterPro

    GO - Biological processi

    1. cell death Source: UniProtKB-KW
    2. lipid catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Lipid degradation, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phospholipase DDHD1 (EC:3.1.1.-)
    Alternative name(s):
    DDHD domain-containing protein 1
    Phosphatidic acid-preferring phospholipase A1 homolog
    Short name:
    PA-PLA1
    Gene namesi
    Name:DDHD1
    Synonyms:KIAA1705
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 14

    Organism-specific databases

    HGNCiHGNC:19714. DDHD1.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Involvement in diseasei

    Spastic paraplegia 28, autosomal recessive (SPG28) [MIM:609340]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Some SPG28 patients also have distal sensory impairment.1 Publication
    Note: The disease is caused by mutations affecting the gene represented in this entry.

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi590 – 5901L → S: No effect on homooligomer formation; when associated with S-593. 1 Publication
    Mutagenesisi593 – 5931I → S: No effect on homooligomer formation; when associated with S-590. 1 Publication
    Mutagenesisi662 – 6621D → A: Markedly decreased enzymatic activity. 1 Publication
    Mutagenesisi848 – 8481D → A: Markedly decreased enzymatic activity. 1 Publication
    Mutagenesisi867 – 8671H → A: Markedly decreased enzymatic activity. 1 Publication
    Mutagenesisi875 – 8751D → A: No effect on enzymatic activity. 1 Publication

    Keywords - Diseasei

    Hereditary spastic paraplegia, Neurodegeneration

    Organism-specific databases

    MIMi609340. phenotype.
    Orphaneti101008. Autosomal recessive spastic paraplegia type 28.
    PharmGKBiPA134861440.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 900900Phospholipase DDHD1PRO_0000079845Add
    BLAST

    Proteomic databases

    MaxQBiQ8NEL9.
    PaxDbiQ8NEL9.
    PRIDEiQ8NEL9.

    PTM databases

    PhosphoSiteiQ8NEL9.

    Expressioni

    Tissue specificityi

    Highly expressed in testis. Also expressed in brain, spleen and lung. Only expressed in cerebellum in fetal brain.1 Publication

    Gene expression databases

    ArrayExpressiQ8NEL9.
    BgeeiQ8NEL9.
    CleanExiHS_DDHD1.
    GenevestigatoriQ8NEL9.

    Organism-specific databases

    HPAiHPA049870.

    Interactioni

    Subunit structurei

    Forms homooligomers and, to a much smaller extent, heterooligomers with DDHD2.1 Publication

    Protein-protein interaction databases

    BioGridi123318. 1 interaction.
    STRINGi9606.ENSP00000350401.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NEL9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini611 – 886276DDHDPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PA-PLA1 family.Curated
    Contains 1 DDHD domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG285690.
    HOGENOMiHOG000007412.
    HOVERGENiHBG059037.
    InParanoidiQ8NEL9.
    KOiK13619.
    OMAiHLALDPC.
    OrthoDBiEOG790G09.
    PhylomeDBiQ8NEL9.
    TreeFamiTF314133.

    Family and domain databases

    InterProiIPR004177. DDHD.
    [Graphical view]
    PfamiPF02862. DDHD. 1 hit.
    [Graphical view]
    PROSITEiPS51043. DDHD. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8NEL9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MNYPGRGSPR SPEHNGRGGG GGAWELGSDA RPAFGGGVCC FEHLPGGDPD    50
    DGDVPLALLR GEPGLHLAPG TDDHNHHLAL DPCLSDENYD FSSAESGSSL 100
    RYYSEGESGG GGSSLSLHPP QQPPLVPTNS GGGGATGGSP GERKRTRLGG 150
    PAARHRYEVV TELGPEEVRW FYKEDKKTWK PFIGYDSLRI ELAFRTLLQT 200
    TGARPQGGDR DGDHVCSPTG PASSSGEDDD EDRACGFCQS TTGHEPEMVE 250
    LVNIEPVCVR GGLYEVDVTQ GECYPVYWNQ ADKIPVMRGQ WFIDGTWQPL 300
    EEEESNLIEQ EHLNCFRGQQ MQENFDIEVS KSIDGKDAVH SFKLSRNHVD 350
    WHSVDEVYLY SDATTSKIAR TVTQKLGFSK ASSSGTRLHR GYVEEATLED 400
    KPSQTTHIVF VVHGIGQKMD QGRIIKNTAM MREAARKIEE RHFSNHATHV 450
    EFLPVEWRSK LTLDGDTVDS ITPDKVRGLR DMLNSSAMDI MYYTSPLYRD 500
    ELVKGLQQEL NRLYSLFCSR NPDFEEKGGK VSIVSHSLGC VITYDIMTGW 550
    NPVRLYEQLL QKEEELPDER WMSYEERHLL DELYITKRRL KEIEERLHGL 600
    KASSMTQTPA LKFKVENFFC MGSPLAVFLA LRGIRPGNTG SQDHILPREI 650
    CNRLLNIFHP TDPVAYRLEP LILKHYSNIS PVQIHWYNTS NPLPYEHMKP 700
    SFLNPAKEPT SVSENEGIST IPSPVTSPVL SRRHYGESIT NIGKASILGA 750
    ASIGKGLGGM LFSRFGRSST TQSSETSKDS MEDEKKPVAS PSATTVGTQT 800
    LPHSSSGFLD SAYFRLQESF FNLPQLLFPE NVMQNKDNAL VELDHRIDFE 850
    LREGLVESRY WSAVTSHTAY WSSLDVALFL LTFMYKHEHD DDAKPNLDPI 900
    Length:900
    Mass (Da):100,435
    Last modified:October 24, 2003 - v2
    Checksum:iD70DAD1A73AC22B8
    GO
    Isoform 2 (identifier: Q8NEL9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

    Show »
    Length:872
    Mass (Da):97,050
    Checksum:iD58636E03DB8BF78
    GO
    Isoform 3 (identifier: Q8NEL9-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-418: Missing.
         813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

    Note: No experimental confirmation available.

    Show »
    Length:454
    Mass (Da):51,554
    Checksum:i06138258AEADA349
    GO
    Isoform 4 (identifier: Q8NEL9-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         337-337: D → DGSGINYS
         813-841: YFRLQESFFNLPQLLFPENVMQNKDNALV → L

    Note: No experimental confirmation available.

    Show »
    Length:879
    Mass (Da):97,729
    Checksum:i80B36E3D1CAE627F
    GO

    Sequence cautioni

    The sequence BAB21796.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence BAB71679.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti109 – 1091G → GGG in AK125372. (PubMed:14702039)Curated
    Sequence conflicti675 – 6751H → R in AAH30703. (PubMed:15489334)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 418418Missing in isoform 3. 2 PublicationsVSP_008628Add
    BLAST
    Alternative sequencei337 – 3371D → DGSGINYS in isoform 4. CuratedVSP_045340
    Alternative sequencei813 – 84129YFRLQ…DNALV → L in isoform 2, isoform 3 and isoform 4. 3 PublicationsVSP_008629Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB051492 mRNA. Translation: BAB21796.1. Different initiation.
    AK058137 mRNA. Translation: BAB71679.1. Different initiation.
    AK125372 mRNA. No translation available.
    AL352979 Genomic DNA. No translation available.
    AL356020 Genomic DNA. No translation available.
    CH471061 Genomic DNA. Translation: EAW80623.1.
    BC018014 mRNA. Translation: AAH18014.1.
    BC030703 mRNA. Translation: AAH30703.1.
    CCDSiCCDS53895.1. [Q8NEL9-1]
    CCDS53896.1. [Q8NEL9-4]
    CCDS9714.1. [Q8NEL9-2]
    RefSeqiNP_001153619.1. NM_001160147.1. [Q8NEL9-4]
    NP_001153620.1. NM_001160148.1. [Q8NEL9-1]
    NP_085140.2. NM_030637.2. [Q8NEL9-2]
    UniGeneiHs.125525.

    Genome annotation databases

    EnsembliENST00000323669; ENSP00000327104; ENSG00000100523. [Q8NEL9-1]
    ENST00000357758; ENSP00000350401; ENSG00000100523. [Q8NEL9-2]
    ENST00000395606; ENSP00000378970; ENSG00000100523. [Q8NEL9-4]
    GeneIDi80821.
    KEGGihsa:80821.
    UCSCiuc001xag.3. human. [Q8NEL9-3]
    uc001xah.3. human. [Q8NEL9-2]
    uc001xai.3. human. [Q8NEL9-1]
    uc001xaj.3. human.

    Polymorphism databases

    DMDMi37999716.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB051492 mRNA. Translation: BAB21796.1 . Different initiation.
    AK058137 mRNA. Translation: BAB71679.1 . Different initiation.
    AK125372 mRNA. No translation available.
    AL352979 Genomic DNA. No translation available.
    AL356020 Genomic DNA. No translation available.
    CH471061 Genomic DNA. Translation: EAW80623.1 .
    BC018014 mRNA. Translation: AAH18014.1 .
    BC030703 mRNA. Translation: AAH30703.1 .
    CCDSi CCDS53895.1. [Q8NEL9-1 ]
    CCDS53896.1. [Q8NEL9-4 ]
    CCDS9714.1. [Q8NEL9-2 ]
    RefSeqi NP_001153619.1. NM_001160147.1. [Q8NEL9-4 ]
    NP_001153620.1. NM_001160148.1. [Q8NEL9-1 ]
    NP_085140.2. NM_030637.2. [Q8NEL9-2 ]
    UniGenei Hs.125525.

    3D structure databases

    ProteinModelPortali Q8NEL9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 123318. 1 interaction.
    STRINGi 9606.ENSP00000350401.

    PTM databases

    PhosphoSitei Q8NEL9.

    Polymorphism databases

    DMDMi 37999716.

    Proteomic databases

    MaxQBi Q8NEL9.
    PaxDbi Q8NEL9.
    PRIDEi Q8NEL9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000323669 ; ENSP00000327104 ; ENSG00000100523 . [Q8NEL9-1 ]
    ENST00000357758 ; ENSP00000350401 ; ENSG00000100523 . [Q8NEL9-2 ]
    ENST00000395606 ; ENSP00000378970 ; ENSG00000100523 . [Q8NEL9-4 ]
    GeneIDi 80821.
    KEGGi hsa:80821.
    UCSCi uc001xag.3. human. [Q8NEL9-3 ]
    uc001xah.3. human. [Q8NEL9-2 ]
    uc001xai.3. human. [Q8NEL9-1 ]
    uc001xaj.3. human.

    Organism-specific databases

    CTDi 80821.
    GeneCardsi GC14M053510.
    HGNCi HGNC:19714. DDHD1.
    HPAi HPA049870.
    MIMi 609340. phenotype.
    614603. gene.
    neXtProti NX_Q8NEL9.
    Orphaneti 101008. Autosomal recessive spastic paraplegia type 28.
    PharmGKBi PA134861440.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG285690.
    HOGENOMi HOG000007412.
    HOVERGENi HBG059037.
    InParanoidi Q8NEL9.
    KOi K13619.
    OMAi HLALDPC.
    OrthoDBi EOG790G09.
    PhylomeDBi Q8NEL9.
    TreeFami TF314133.

    Miscellaneous databases

    GenomeRNAii 80821.
    NextBioi 71223.
    PROi Q8NEL9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8NEL9.
    Bgeei Q8NEL9.
    CleanExi HS_DDHD1.
    Genevestigatori Q8NEL9.

    Family and domain databases

    InterProi IPR004177. DDHD.
    [Graphical view ]
    Pfami PF02862. DDHD. 1 hit.
    [Graphical view ]
    PROSITEi PS51043. DDHD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O.
      DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Brain.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 357-900 (ISOFORMS 2/4).
      Tissue: Fetal brain and Testis.
    3. "The DNA sequence and analysis of human chromosome 14."
      Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
      , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
      Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Brain and Testis.
    6. "Cloning of a phosphatidic acid-preferring phospholipase A1 from bovine testis."
      Higgs H.N., Han M.H., Johnson G.E., Glomset J.A.
      J. Biol. Chem. 273:5468-5477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.
    7. "p125 is localized in endoplasmic reticulum exit sites and involved in their organization."
      Shimoi W., Ezawa I., Nakamoto K., Uesaki S., Gabreski G., Aridor M., Yamamoto A., Nagahama M., Tagaya M., Tani K.
      J. Biol. Chem. 280:10141-10148(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
    8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. Cited for: INVOLVEMENT IN SPG28.
    10. "Roles of SAM and DDHD domains in mammalian intracellular phospholipase A1 KIAA0725p."
      Inoue H., Baba T., Sato S., Ohtsuki R., Takemori A., Watanabe T., Tagaya M., Tani K.
      Biochim. Biophys. Acta 1823:930-939(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBUNIT, HOMOOLIGOMER FORMATION, INTERACTION WITH DDHD2, MUTAGENESIS OF LEU-590; ILE-593; ASP-662; ASP-848; HIS-867 AND ASP-875.

    Entry informationi

    Entry nameiDDHD1_HUMAN
    AccessioniPrimary (citable) accession number: Q8NEL9
    Secondary accession number(s): G5E9D1
    , Q8WVH3, Q96LL2, Q9C0F8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 24, 2003
    Last sequence update: October 24, 2003
    Last modified: October 1, 2014
    This is version 95 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 14
      Human chromosome 14: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3