Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Coiled-coil domain-containing protein 54

Gene

CCDC54

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 54
Alternative name(s):
Testis development protein NYD-SP17
Gene namesi
Name:CCDC54
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000138483.2
HGNCiHGNC:30703 CCDC54
neXtProtiNX_Q8NEL0

Pathology & Biotechi

Organism-specific databases

DisGeNETi84692
OpenTargetsiENSG00000138483
PharmGKBiPA142672170

Polymorphism and mutation databases

BioMutaiCCDC54
DMDMi147637038

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002866681 – 328Coiled-coil domain-containing protein 54Add BLAST328

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei182PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8NEL0
PeptideAtlasiQ8NEL0
PRIDEiQ8NEL0

PTM databases

iPTMnetiQ8NEL0
PhosphoSitePlusiQ8NEL0

Expressioni

Gene expression databases

BgeeiENSG00000138483
CleanExiHS_CCDC54
ExpressionAtlasiQ8NEL0 baseline and differential
GenevisibleiQ8NEL0 HS

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261058

Structurei

3D structure databases

ProteinModelPortaliQ8NEL0
SMRiQ8NEL0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili93 – 151Sequence analysisAdd BLAST59

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IIYS Eukaryota
ENOG41116C5 LUCA
GeneTreeiENSGT00390000008948
HOGENOMiHOG000111421
HOVERGENiHBG096794
InParanoidiQ8NEL0
OMAiTWIKLTF
OrthoDBiEOG091G1BRY
PhylomeDBiQ8NEL0
TreeFamiTF338361

Family and domain databases

InterProiView protein in InterPro
IPR037758 Ccdc54
PANTHERiPTHR37880 PTHR37880, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NEL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTLHTKRVK AAARQMWTSN LSKVRQSLKN VYHKCKIRHQ DSTGYPTVTS
60 70 80 90 100
DDCNQDDDSY DGKMNLPVVL QDVKTAQVEL FSQMTDIVHM IPKVQEKTDL
110 120 130 140 150
YQKQMEVLET RMNVNEDKQC TTTKDILSMK EDIKALKKKV TELEIQNSCS
160 170 180 190 200
TIHCLEILEG ERGKEITELL YKLIQPATLK NTLASTDMEI SSAEPEKVPS
210 220 230 240 250
YPKSTDHLEK KTISPQMKTL KKRNHQNASR SFEKAKPNIY IYPDFSTWIK
260 270 280 290 300
LTFVHGGKWT FFLSATKLEE FIQWLLSRPT ILPEEPQVIT QRYCPFTGPI
310 320
LSLTTICLSI FNNIYGFICS LKEEVTRL
Length:328
Mass (Da):37,886
Last modified:May 15, 2007 - v2
Checksum:i238D593D97AF3D11
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03215138R → Q1 PublicationCorresponds to variant dbSNP:rs709564Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367469 mRNA Translation: AAK53405.1
AK058091 mRNA Translation: BAB71661.1
BC030780 mRNA Translation: AAH30780.1
CCDSiCCDS2949.1
RefSeqiNP_115989.1, NM_032600.2
UniGeneiHs.164799

Genome annotation databases

EnsembliENST00000261058; ENSP00000261058; ENSG00000138483
GeneIDi84692
KEGGihsa:84692
UCSCiuc003dwi.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCCD54_HUMAN
AccessioniPrimary (citable) accession number: Q8NEL0
Secondary accession number(s): Q96A43
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: March 28, 2018
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health