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Protein

Protein ZNF738

Gene

ZNF738

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Caution

Despite its name, it does not contain a canonical C2H2-type zinc-finger.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ZNF738
Gene namesi
Name:ZNF738
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000172687.13
HGNCiHGNC:32469 ZNF738
neXtProtiNX_Q8NE65

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172687

Polymorphism and mutation databases

DMDMi74730211

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002748791 – 137Protein ZNF738Add BLAST137

Proteomic databases

PaxDbiQ8NE65
PeptideAtlasiQ8NE65
PRIDEiQ8NE65

PTM databases

iPTMnetiQ8NE65
PhosphoSitePlusiQ8NE65

Expressioni

Gene expression databases

BgeeiENSG00000172687
CleanExiHS_ZNF738
ExpressionAtlasiQ8NE65 baseline and differential
GenevisibleiQ8NE65 HS

Organism-specific databases

HPAiHPA059135

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000311957

Structurei

3D structure databases

ProteinModelPortaliQ8NE65
SMRiQ8NE65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 106KRABPROSITE-ProRule annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00910000144150
HOGENOMiHOG000231475
HOVERGENiHBG067759
InParanoidiQ8NE65
OMAiQSVNICF
OrthoDBiEOG091G0RKV
PhylomeDBiQ8NE65
TreeFamiTF342644

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NE65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDLRYGVYP VKGASGYPGA ERNLLEYSYF EKGPLTFRDV VIEFSQEEWQ
60 70 80 90 100
CLDTAQQDLY RKVMLENFRN LVFLGIDVSK PDLITCLEQG KDPWNMKRHS
110 120 130
MVATPPESGV LKFPTIIILL SRCFFQSVNI CFIYLEP
Length:137
Mass (Da):15,884
Last modified:October 1, 2002 - v1
Checksum:i799B9BE0A3B61C43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291002 mRNA Translation: BAF83691.1
AK291193 mRNA Translation: BAF83882.1
AC010615 Genomic DNA No translation available.
AC022432 Genomic DNA No translation available.
BC034499 mRNA No translation available.
UniGeneiHs.124384

Genome annotation databases

EnsembliENST00000311015; ENSP00000311957; ENSG00000172687
UCSCiuc002nps.5 human

Similar proteinsi

Entry informationi

Entry nameiZN738_HUMAN
AccessioniPrimary (citable) accession number: Q8NE65
Secondary accession number(s): A8K4N7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: October 1, 2002
Last modified: February 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome