Q8NDB2 (BANK1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
B-cell scaffold protein with ankyrin repeats

Gene names

Name:

BANK1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	785 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in B-cell receptor (BCR)-induced Ca2+ mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. Ref.1
Subunit structure	Interacts with LYN, ITPR1 and ITPR2. Ref.1
Tissue specificity	Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19+ B-cells, with very low expression in other cell populations. Ref.1 Ref.2
Post-translational modification	Phosphorylated on tyrosines upon BCR activation. Ref.1
Involvement in disease	Systemic lupus erythematosus (SLE) [MIM:152700]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
Sequence similarities	Contains 2 ANK repeats. Contains 1 DBB domain.
Sequence caution	The sequence BAA91337.1 differs from that shown. Reason: Frameshift at positions 571 and 681.

Ontologies

Keywords
Biological process	B-cell activation
Coding sequence diversity	Alternative splicing Polymorphism
Disease	Systemic lupus erythematosus
Domain	ANK repeat Repeat
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	B cell activation Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8NDB2-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8NDB2-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-14: Missing.
     15-23: PAPCGPAPP → MVNCHLKI

Note: No experimental confirmation available.

Isoform 3 (identifier: Q8NDB2-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-30: Missing.

Isoform 4 (identifier: Q8NDB2-4)

Also known as: delta2;

The sequence of this isoform differs from the canonical sequence as follows:
     24-156: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 785	785	B-cell scaffold protein with ankyrin repeats		PRO_0000251927
Regions
	Domain	200 – 327	128	DBB
	Repeat	342 – 371	30	ANK 1
	Repeat	378 – 408	31	ANK 2
	Region	1 – 154	154	Interaction with ITPR2
Natural variations
	Alternative sequence	1 – 30	30	Missing in isoform 3.		VSP_020803
	Alternative sequence	1 – 14	14	Missing in isoform 2.		VSP_020804
	Alternative sequence	15 – 23	9	PAPCGPAPP → MVNCHLKI in isoform 2.		VSP_020805
	Alternative sequence	24 – 156	133	Missing in isoform 4.		VSP_034214
	Natural variant	61	1	R → H Influences susceptibility to SLE. Ref.2 Corresponds to variant rs10516487 [ dbSNP | Ensembl ].		VAR_027729
	Natural variant	383	1	A → T Influences susceptibility to SLE. Ref.2 Ref.4 Corresponds to variant rs3733197 [ dbSNP | Ensembl ].		VAR_027730
	Natural variant	650	1	C → R. Ref.1 Ref.2 Ref.4 Ref.5 Ref.7 Corresponds to variant rs3113676 [ dbSNP | Ensembl ].		VAR_027731
Experimental info
	Sequence conflict	143	1	P → L in BAA91337. Ref.4
	Sequence conflict	209	1	N → D in BAC03685. Ref.4
	Sequence conflict	303	1	S → R in BAF84822. Ref.4
	Sequence conflict	436	1	H → R in BAB79255. Ref.1
	Sequence conflict	557	1	E → D in BAA91337. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 5, 2010. Version 3. Checksum: A4A833E4A13FC6A6	FASTA	785	89,282
	10 20 30 40 50 60 MLPAAPGKGL GSPDPAPCGP APPGNTKDII MIYEEDAEEW ALYLTEVFLH VVKREAILLY 70 80 90 100 110 120 RLENFSFRHL ELLNLTSYKC KLLILSNSLL RDLTPKKCQF LEKILHSPKS VVTLLCGVKS 130 140 150 160 170 180 SDQLYELLNI SQSRWEISTE QEPEDYISVI QSIIFKDSED YFEVNIPTDL RAKHSGEISE 190 200 210 220 230 240 RKEIEELSEA SRNTIPLAVV LPTEIPCENP GEIFIILRDE VIGDTVEVEF TSSNKRIRTR 250 260 270 280 290 300 PALWNKKVWC MKALEFPAGS VHVNVYCDGI VKATTKIKYY PTAKAKECLF RMADSGESLC 310 320 330 340 350 360 QNSIEELDGV LTSIFKHEIP YYEFQSLQTE ICSQNKYTHF KELPTLLHCA AKFGLKNLAI 370 380 390 400 410 420 HLLQCSGATW ASKMKNMEGS DPAHIAERHG HKELKKIFED FSIQEIDINN EQENDYEEDI 430 440 450 460 470 480 ASFSTYIPST QNPAFHHESR KTYGQSADGA EANEMEGEGK QNGSGMETKH SPLEVGSESS 490 500 510 520 530 540 EDQYDDLYVF IPGADPENNS QEPLMSSRPP LPPPRPVANA FQLERPHFTL PGTMVEGQME 550 560 570 580 590 600 RSQNWGHPGV RQETGDEPKG EKEKKEEEKE QEEEEDPYTF AEIDDSEYDM ILANLSIKKK 610 620 630 640 650 660 TGSRSFIINR PPAPTPRPTS IPPKEETTPY IAQVFQQKTA RRQSDDDKFC GLPKKQDRAR 670 680 690 700 710 720 IESPAFSTLR GCLTDGQEEL ILLQEKVKNG KMSMDEALEK FKHWQMGKSG LEMIQQEKLR 730 740 750 760 770 780 QLRDCIIGKR PEEENVYNKL TIVHHPGGKE TAHNENKFYN VHFSNKLPAR PQVEKEFGFC CKKDH
	Isoform 2 [UniParc]. Checksum: 4A4B533F885A3C34	FASTA	770	88,141
	10 20 30 40 50 60 MVNCHLKIGN TKDIIMIYEE DAEEWALYLT EVFLHVVKRE AILLYRLENF SFRHLELLNL 70 80 90 100 110 120 TSYKCKLLIL SNSLLRDLTP KKCQFLEKIL HSPKSVVTLL CGVKSSDQLY ELLNISQSRW 130 140 150 160 170 180 EISTEQEPED YISVIQSIIF KDSEDYFEVN IPTDLRAKHS GEISERKEIE ELSEASRNTI 190 200 210 220 230 240 PLAVVLPTEI PCENPGEIFI ILRDEVIGDT VEVEFTSSNK RIRTRPALWN KKVWCMKALE 250 260 270 280 290 300 FPAGSVHVNV YCDGIVKATT KIKYYPTAKA KECLFRMADS GESLCQNSIE ELDGVLTSIF 310 320 330 340 350 360 KHEIPYYEFQ SLQTEICSQN KYTHFKELPT LLHCAAKFGL KNLAIHLLQC SGATWASKMK 370 380 390 400 410 420 NMEGSDPAHI AERHGHKELK KIFEDFSIQE IDINNEQEND YEEDIASFST YIPSTQNPAF 430 440 450 460 470 480 HHESRKTYGQ SADGAEANEM EGEGKQNGSG METKHSPLEV GSESSEDQYD DLYVFIPGAD 490 500 510 520 530 540 PENNSQEPLM SSRPPLPPPR PVANAFQLER PHFTLPGTMV EGQMERSQNW GHPGVRQETG 550 560 570 580 590 600 DEPKGEKEKK EEEKEQEEEE DPYTFAEIDD SEYDMILANL SIKKKTGSRS FIINRPPAPT 610 620 630 640 650 660 PRPTSIPPKE ETTPYIAQVF QQKTARRQSD DDKFCGLPKK QDRARIESPA FSTLRGCLTD 670 680 690 700 710 720 GQEELILLQE KVKNGKMSMD EALEKFKHWQ MGKSGLEMIQ QEKLRQLRDC IIGKRPEEEN 730 740 750 760 770 VYNKLTIVHH PGGKETAHNE NKFYNVHFSN KLPARPQVEK EFGFCCKKDH
	Isoform 3 [UniParc]. Checksum: 08ACB3617BC22FF0	FASTA	755	86,460
	10 20 30 40 50 60 MIYEEDAEEW ALYLTEVFLH VVKREAILLY RLENFSFRHL ELLNLTSYKC KLLILSNSLL 70 80 90 100 110 120 RDLTPKKCQF LEKILHSPKS VVTLLCGVKS SDQLYELLNI SQSRWEISTE QEPEDYISVI 130 140 150 160 170 180 QSIIFKDSED YFEVNIPTDL RAKHSGEISE RKEIEELSEA SRNTIPLAVV LPTEIPCENP 190 200 210 220 230 240 GEIFIILRDE VIGDTVEVEF TSSNKRIRTR PALWNKKVWC MKALEFPAGS VHVNVYCDGI 250 260 270 280 290 300 VKATTKIKYY PTAKAKECLF RMADSGESLC QNSIEELDGV LTSIFKHEIP YYEFQSLQTE 310 320 330 340 350 360 ICSQNKYTHF KELPTLLHCA AKFGLKNLAI HLLQCSGATW ASKMKNMEGS DPAHIAERHG 370 380 390 400 410 420 HKELKKIFED FSIQEIDINN EQENDYEEDI ASFSTYIPST QNPAFHHESR KTYGQSADGA 430 440 450 460 470 480 EANEMEGEGK QNGSGMETKH SPLEVGSESS EDQYDDLYVF IPGADPENNS QEPLMSSRPP 490 500 510 520 530 540 LPPPRPVANA FQLERPHFTL PGTMVEGQME RSQNWGHPGV RQETGDEPKG EKEKKEEEKE 550 560 570 580 590 600 QEEEEDPYTF AEIDDSEYDM ILANLSIKKK TGSRSFIINR PPAPTPRPTS IPPKEETTPY 610 620 630 640 650 660 IAQVFQQKTA RRQSDDDKFC GLPKKQDRAR IESPAFSTLR GCLTDGQEEL ILLQEKVKNG 670 680 690 700 710 720 KMSMDEALEK FKHWQMGKSG LEMIQQEKLR QLRDCIIGKR PEEENVYNKL TIVHHPGGKE 730 740 750 TAHNENKFYN VHFSNKLPAR PQVEKEFGFC CKKDH
	Isoform 4 (delta2) [UniParc]. Checksum: 5751DEA277FF9DCA	FASTA	652	73,674
	10 20 30 40 50 60 MLPAAPGKGL GSPDPAPCGP APPDSEDYFE VNIPTDLRAK HSGEISERKE IEELSEASRN 70 80 90 100 110 120 TIPLAVVLPT EIPCENPGEI FIILRDEVIG DTVEVEFTSS NKRIRTRPAL WNKKVWCMKA 130 140 150 160 170 180 LEFPAGSVHV NVYCDGIVKA TTKIKYYPTA KAKECLFRMA DSGESLCQNS IEELDGVLTS 190 200 210 220 230 240 IFKHEIPYYE FQSLQTEICS QNKYTHFKEL PTLLHCAAKF GLKNLAIHLL QCSGATWASK 250 260 270 280 290 300 MKNMEGSDPA HIAERHGHKE LKKIFEDFSI QEIDINNEQE NDYEEDIASF STYIPSTQNP 310 320 330 340 350 360 AFHHESRKTY GQSADGAEAN EMEGEGKQNG SGMETKHSPL EVGSESSEDQ YDDLYVFIPG 370 380 390 400 410 420 ADPENNSQEP LMSSRPPLPP PRPVANAFQL ERPHFTLPGT MVEGQMERSQ NWGHPGVRQE 430 440 450 460 470 480 TGDEPKGEKE KKEEEKEQEE EEDPYTFAEI DDSEYDMILA NLSIKKKTGS RSFIINRPPA 490 500 510 520 530 540 PTPRPTSIPP KEETTPYIAQ VFQQKTARRQ SDDDKFCGLP KKQDRARIES PAFSTLRGCL 550 560 570 580 590 600 TDGQEELILL QEKVKNGKMS MDEALEKFKH WQMGKSGLEM IQQEKLRQLR DCIIGKRPEE 610 620 630 640 650 ENVYNKLTIV HHPGGKETAH NENKFYNVHF SNKLPARPQV EKEFGFCCKK DH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor." Yokoyama K., Su I., Tezuka T., Yasuda T., Mikoshiba K., Tarakhovsky A., Yamamoto T. EMBO J. 21:83-92(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), TISSUE SPECIFICITY, PHOSPHORYLATION, INTERACTION WITH LYN; ITPR1 AND ITPR2, FUNCTION, VARIANT ARG-650. Tissue: B-cell.
[2]	"Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus." Kozyrev S.V., Abelson A.-K., Wojcik J., Zaghlool A., Linga Reddy M.V.P., Sanchez E., Gunnarsson I., Svenungsson E., Sturfelt G., Joensen A., Truedsson L., Pons-Estel B.A., Witte T., D'Alfonso S., Barizzone N., Danieli M.G., Gutierrez C., Suarez A. , Junker P., Laustrup H., Gonzalez-Escribano M.F., Martin J., Abderrahim H., Alarcon-Riquelme M.E. Nat. Genet. 40:211-216(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), TISSUE SPECIFICITY, VARIANTS HIS-61; THR-383 AND ARG-650.
[3]	Erratum Kozyrev S.V., Abelson A.-K., Wojcik J., Zaghlool A., Linga Reddy M.V.P., Sanchez E., Gunnarsson I., Svenungsson E., Sturfelt G., Joensen A., Truedsson L., Pons-Estel B.A., Witte T., D'Alfonso S., Barizzone N., Danieli M.G., Gutierrez C., Suarez A. , Junker P., Laustrup H., Gonzalez-Escribano M.F., Martin J., Abderrahim H., Alarcon-Riquelme M.E. Nat. Genet. 40:484-484(2008)
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3), VARIANTS THR-383 AND ARG-650. Tissue: Brain, Ileal mucosa and Synovium.
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ARG-650. Tissue: Lymph node.
[6]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ARG-650. Tissue: Blood.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB063170 mRNA. Translation: BAB79255.1. EU051376 mRNA. Translation: ABW74340.1. AK000713 mRNA. Translation: BAA91337.1. Frameshift. AK091523 mRNA. Translation: BAC03685.1. AK292133 mRNA. Translation: BAF84822.1. AL834291 mRNA. Translation: CAD38965.2. AC093694 Genomic DNA. No translation available. AC095062 Genomic DNA. No translation available. AC109928 Genomic DNA. No translation available. AP002075 Genomic DNA. No translation available. BC032241 mRNA. Translation: AAH32241.2.
IPI	IPI00179337. IPI00787141. IPI00787434. IPI00895834.
RefSeq	NP_001077376.2. NM_001083907.2. NP_001120979.2. NM_001127507.2. NP_060405.4. NM_017935.4.
UniGene	Hs.480400.
3D structure databases
ProteinModelPortal	Q8NDB2.
SMR	Q8NDB2. Positions 345-400.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8NDB2. 5 interactions.
STRING	9606.ENSP00000320509.
PTM databases
PhosphoSite	Q8NDB2.
Polymorphism databases
DMDM	308153627.
Proteomic databases
PaxDb	Q8NDB2.
PRIDE	Q8NDB2.
Protocols and materials databases
DNASU	55024.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000322953; ENSP00000320509; ENSG00000153064. ENST00000428908; ENSP00000412748; ENSG00000153064. ENST00000444316; ENSP00000388817; ENSG00000153064. ENST00000504592; ENSP00000421443; ENSG00000153064. ENST00000508653; ENSP00000422314; ENSG00000153064.
GeneID	55024.
KEGG	hsa:55024.
UCSC	uc003hvx.4. human. uc003hvy.4. human. uc010ill.3. human.
Organism-specific databases
CTD	55024.
GeneCards	GC04P102332.
HGNC	HGNC:18233. BANK1.
HPA	HPA037002.
MIM	152700. phenotype. 610292. gene.
neXtProt	NX_Q8NDB2.
PharmGKB	PA128394677.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG123833.
HOVERGEN	HBG080888.
InParanoid	Q8NDB2.
OMA	NVYCDGI.
Gene expression databases
Bgee	Q8NDB2.
CleanEx	HS_BANK1.
Genevestigator	Q8NDB2.
GermOnline	ENSG00000153064. Homo sapiens.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR020683. Ankyrin_rpt-contain_dom. IPR017893. DBB_domain. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. False negative. PS50088. ANK_REPEAT. False negative. PS51376. DBB. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	BANK1. human.
GenomeRNAi	55024.
NextBio	58410.
SOURCE	Search...

Entry information

Entry name

BANK1_HUMAN

Accession

Primary (citable) accession number: Q8NDB2
Secondary accession number(s): A8K7W8 , B0F3S2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	October 5, 2010
Last modified:	May 1, 2013
This is version 78 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.