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Protein

LRRN4 C-terminal-like protein

Gene

LRRN4CL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
LRRN4 C-terminal-like protein
Gene namesi
Name:LRRN4CL
ORF Names:UNQ728/PRO1410
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000177363.4
HGNCiHGNC:33724 LRRN4CL
neXtProtiNX_Q8ND94

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 194ExtracellularSequence analysisAdd BLAST172
Transmembranei195 – 215HelicalSequence analysisAdd BLAST21
Topological domaini216 – 238CytoplasmicSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000177363
PharmGKBiPA162394685

Polymorphism and mutation databases

DMDMi74760169

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000031775223 – 238LRRN4 C-terminal-like proteinAdd BLAST216

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi132N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8ND94
PeptideAtlasiQ8ND94
PRIDEiQ8ND94
ProteomicsDBi72993

Expressioni

Gene expression databases

BgeeiENSG00000177363
CleanExiHS_LRRN4CL
GenevisibleiQ8ND94 HS

Organism-specific databases

HPAiHPA050317

Interactioni

Protein-protein interaction databases

BioGridi128684, 5 interactors
IntActiQ8ND94, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ8ND94
SMRiQ8ND94
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 176Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST95

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi29 – 32Poly-Glu4

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IXSX Eukaryota
ENOG410YNYQ LUCA
GeneTreeiENSGT00530000064159
HOGENOMiHOG000113385
HOVERGENiHBG069577
InParanoidiQ8ND94
OMAiCRHLQVP
OrthoDBiEOG091G0O16
PhylomeDBiQ8ND94

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8ND94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGSPCLLWL LAVTFLVPRA QPLAPQDFEE EEADETETAW PPLPAVPCDY
60 70 80 90 100
DHCRHLQVPC KELQRVGPAA CLCPGLSSPA QPPDPPRMGE VRIAAEEGRA
110 120 130 140 150
VVHWCAPFSP VLHYWLLLWD GSEAAQKGPP LNATVRRAEL KGLKPGGIYV
160 170 180 190 200
VCVVAANEAG ASRVPQAGGE GLEGADIPAF GPCSRLAVPP NPRTLVHAAV
210 220 230
GVGTALALLS CAALVWHFCL RDRWGCPRRA AARAAGAL
Length:238
Mass (Da):25,262
Last modified:October 1, 2002 - v1
Checksum:iC7300A7D5A9E3095
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti34D → N in BAF84023 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358354 mRNA Translation: AAQ88720.1
AK291334 mRNA Translation: BAF84023.1
AL834319 mRNA Translation: CAD38988.1
BC053902 mRNA Translation: AAH53902.1
CCDSiCCDS8030.1
RefSeqiNP_981967.1, NM_203422.3
UniGeneiHs.427449

Genome annotation databases

EnsembliENST00000317449; ENSP00000325808; ENSG00000177363
GeneIDi221091
KEGGihsa:221091
UCSCiuc001nun.3 human

Similar proteinsi

Entry informationi

Entry nameiLRN4L_HUMAN
AccessioniPrimary (citable) accession number: Q8ND94
Secondary accession number(s): A8K5L9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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