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Q8ND76 (CCNY_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 116. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cyclin-Y

Short name=Cyc-Y
Alternative name(s):
Cyclin box protein 1
Cyclin fold protein 1
cyclin-X
Gene names
Name:CCNY
Synonyms:C10orf9, CBCP1, CFP1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. Ref.1 Ref.2 Ref.14 Ref.18

Subunit structure

Interacts with CDK14, CDK16 and LRP6. Ref.1 Ref.14 Ref.18

Subcellular location

Cell membrane; Lipid-anchor; Cytoplasmic side Ref.1 Ref.2 Ref.14 Ref.18.

Isoform 3: Nucleus Ref.1 Ref.2 Ref.14 Ref.18.

Tissue specificity

Widely expressed. Ref.2

Developmental stage

Enriched at G2/M. Ref.14

Post-translational modification

Ubiquitinated; leading to its degradation. Ref.14

Sequence similarities

Belongs to the cyclin family. Cyclin Y subfamily.

Contains 1 cyclin N-terminal domain.

Sequence caution

The sequence AAH69224.1 differs from that shown. Reason: Erroneous initiation.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

CDK14O9492111EBI-1049189,EBI-1043945

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q8ND76-1)

Also known as: b;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q8ND76-2)

Also known as: a;

The sequence of this isoform differs from the canonical sequence as follows:
     52-76: Missing.
Isoform 3 (identifier: Q8ND76-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-54: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 341340Cyclin-Y
PRO_0000080514

Regions

Domain143 – 265123Cyclin N-terminal

Amino acid modifications

Modified residue251Phosphoserine Ref.13
Modified residue3261Phosphoserine Ref.17 Ref.18
Lipidation21N-myristoyl glycine Ref.1 Ref.14

Natural variations

Alternative sequence1 – 5454Missing in isoform 3.
VSP_014833
Alternative sequence52 – 7625Missing in isoform 2.
VSP_014834

Experimental info

Mutagenesis21G → A: Induces a diffuse cytoplasmic localization. Ref.1 Ref.14
Mutagenesis31N → A: No effect on subcellular location. Ref.1
Sequence conflict781R → G in AAL78998. Ref.4
Sequence conflict1181Y → H in AAL78999. Ref.4
Sequence conflict1551S → C in AAS79427. Ref.1
Sequence conflict1551S → C in AAL07802. Ref.3
Sequence conflict1711I → M in AAS79427. Ref.1
Sequence conflict1711I → M in AAL07802. Ref.3
Sequence conflict1901I → V in BAB71409. Ref.5
Sequence conflict2161V → A in AAS79427. Ref.1
Sequence conflict2161V → A in AAL07802. Ref.3
Sequence conflict2501N → S in BAB71409. Ref.5
Sequence conflict2681S → F in AAS79427. Ref.1
Sequence conflict2681S → F in AAL07802. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (b) [UniParc].

Last modified September 13, 2004. Version 2.
Checksum: 949FDE1EE45C2C6E

FASTA34139,337
        10         20         30         40         50         60 
MGNTTSCCVS SSPKLRRNAH SRLESYRPDT DLSREDTGCN LQHISDRENI DDLNMEFNPS 

        70         80         90        100        110        120 
DHPRASTIFL SKSQTDVREK RKSLFINHHP PGQIARKYSS CSTIFLDDST VSQPNLKYTI 

       130        140        150        160        170        180 
KCVALAIYYH IKNRDPDGRM LLDIFDENLH PLSKSEVPPD YDKHNPEQKQ IYRFVRTLFS 

       190        200        210        220        230        240 
AAQLTAECAI VTLVYLERLL TYAEIDICPA NWKRIVLGAI LLASKVWDDQ AVWNVDYCQI 

       250        260        270        280        290        300 
LKDITVEDMN ELERQFLELL QFNINVPSSV YAKYYFDLRS LAEANNLSFP LEPLSRERAH 

       310        320        330        340 
KLEAISRLCE DKYKDLRRSA RKRSASADNL TLPRWSPAII S 

« Hide

Isoform 2 (a) [UniParc].

Checksum: D9DC97553928235E
Show »

FASTA31636,504
Isoform 3 [UniParc].

Checksum: 88D15913BF680A01
Show »

FASTA28733,245

References

« Hide 'large scale' references
[1]"Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1."
Jiang M., Gao Y., Yang T., Zhu X., Chen J.
FEBS Lett. 583:2171-2178(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CDK14, MYRISTOYLATION AT GLY-2, MUTAGENESIS OF GLY-2 AND ASN-3.
[2]"Identification and characterization of cyclin X which activates transcriptional activities of c-Myc."
Li X., Wang X., Liu G., Li R., Yu L.
Mol. Biol. Rep. 36:97-103(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
Tissue: Testis.
[3]"Identification and characterization of CBCP1, a novel gene located on human chromosome 10."
Gong L., Wu K.
Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[4]"Human cyclin fold protein 1."
Shannon M.
Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
[5]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
Tissue: Testis.
[6]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Tissue: Brain.
[7]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[9]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
Tissue: Brain, Cerebellum, Neuroblastoma and Testis.
[10]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[11]"Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J.
J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: T-cell.
[12]"Phosphoproteome of resting human platelets."
Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J., Schuetz C., Walter U., Gambaryan S., Sickmann A.
J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Platelet.
[13]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[14]"Cell cycle control of wnt receptor activation."
Davidson G., Shen J., Huang Y.L., Su Y., Karaulanov E., Bartscherer K., Hassler C., Stannek P., Boutros M., Niehrs C.
Dev. Cell 17:788-799(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, INTERACTION WITH CDK14 AND LRP6, UBIQUITINATION, MYRISTOYLATION AT GLY-2, MUTAGENESIS OF GLY-2.
[15]"Large-scale proteomics analysis of the human kinome."
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H.
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[16]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[17]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-326, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[18]"Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis."
Mikolcevic P., Sigl R., Rauch V., Hess M.W., Pfaller K., Barisic M., Pelliniemi L.J., Boesl M., Geley S.
Mol. Cell. Biol. 32:868-879(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CDK16, PHOSPHORYLATION AT SER-326.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY504868 mRNA. Translation: AAS79427.1.
AF429969 mRNA. Translation: AAP97301.1.
AF413522 mRNA. Translation: AAL07802.1.
AF465728 mRNA. Translation: AAL78998.1.
AF465729 mRNA. Translation: AAL78999.1.
AK057280 mRNA. Translation: BAB71409.1.
AL834355 mRNA. Translation: CAD39020.2.
AL592445, AL121749, AL603824 Genomic DNA. Translation: CAH70072.1.
AL592445 expand/collapse EMBL AC list , AL121749, AL603824, AL117336 Genomic DNA. Translation: CAH70073.1.
AL603824, AL121749, AL592445 Genomic DNA. Translation: CAH71567.1.
AL603824 expand/collapse EMBL AC list , AL121749, AL592445, AL117336 Genomic DNA. Translation: CAH71568.1.
AL117336 expand/collapse EMBL AC list , AL121749, AL603824, AL592445 Genomic DNA. Translation: CAH72501.1.
AL121749, AL603824, AL592445 Genomic DNA. Translation: CAH73707.1.
AL121749 expand/collapse EMBL AC list , AL603824, AL592445, AL117336 Genomic DNA. Translation: CAH73709.1.
CH471072 Genomic DNA. Translation: EAW85912.1.
CH471072 Genomic DNA. Translation: EAW85913.1.
CH471072 Genomic DNA. Translation: EAW85914.1.
BC069224 mRNA. Translation: AAH69224.1. Different initiation.
BC094815 mRNA. Translation: AAH94815.1.
BC104773 mRNA. Translation: AAI04774.1.
BC104801 mRNA. Translation: AAI04802.1.
BC143450 mRNA. Translation: AAI43451.1.
BC143455 mRNA. Translation: AAI43456.1.
RefSeqNP_001269781.1. NM_001282852.1.
NP_001269782.1. NM_001282853.1.
NP_001269783.1. NM_001282854.1.
NP_659449.3. NM_145012.5.
NP_859049.2. NM_181698.3.
UniGeneHs.14745.
Hs.564123.
Hs.651463.
Hs.714184.

3D structure databases

ProteinModelPortalQ8ND76.
SMRQ8ND76. Positions 166-278.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid128575. 3 interactions.
IntActQ8ND76. 1 interaction.
MINTMINT-1649053.

PTM databases

PhosphoSiteQ8ND76.

Polymorphism databases

DMDM71658801.

Proteomic databases

PaxDbQ8ND76.
PRIDEQ8ND76.

Protocols and materials databases

DNASU219771.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000265375; ENSP00000265375; ENSG00000108100. [Q8ND76-3]
ENST00000339497; ENSP00000344275; ENSG00000108100. [Q8ND76-2]
ENST00000374704; ENSP00000363836; ENSG00000108100. [Q8ND76-1]
ENST00000374706; ENSP00000363838; ENSG00000108100. [Q8ND76-3]
GeneID219771.
KEGGhsa:219771.
UCSCuc001iyu.4. human. [Q8ND76-1]
uc009xmb.3. human. [Q8ND76-2]

Organism-specific databases

CTD219771.
GeneCardsGC10P035576.
HGNCHGNC:23354. CCNY.
HPAHPA036290.
MIM612786. gene.
neXtProtNX_Q8ND76.
PharmGKBPA162381980.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG303674.
HOVERGENHBG058985.
InParanoidQ8ND76.
OMAYDKHDPE.
PhylomeDBQ8ND76.
TreeFamTF314464.

Enzyme and pathway databases

SignaLinkQ8ND76.

Gene expression databases

BgeeQ8ND76.
CleanExHS_CCNY.
GenevestigatorQ8ND76.

Family and domain databases

Gene3D1.10.472.10. 1 hit.
InterProIPR013763. Cyclin-like.
IPR006671. Cyclin_N.
IPR012399. Cyclin_Y.
[Graphical view]
PfamPF00134. Cyclin_N. 1 hit.
[Graphical view]
PIRSFPIRSF028934. Cyclin_CG14939. 1 hit.
SMARTSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMSSF47954. SSF47954. 1 hit.
ProtoNetSearch...

Other

ChiTaRSCCNY. human.
GeneWikiCCNY_(gene).
GenomeRNAi219771.
NextBio90749.
PROQ8ND76.
SOURCESearch...

Entry information

Entry nameCCNY_HUMAN
AccessionPrimary (citable) accession number: Q8ND76
Secondary accession number(s): B7ZKX9 expand/collapse secondary AC list , D3DRY9, Q2M3V4, Q2TU96, Q6NT86, Q7Z4U7, Q8TEX2, Q8TEX3, Q96M99, Q96P45
Entry history
Integrated into UniProtKB/Swiss-Prot: August 2, 2005
Last sequence update: September 13, 2004
Last modified: April 16, 2014
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM