Q8ND76 (CCNY_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-Y
Short name=Cyc-Y

Alternative name(s):
Cyclin box protein 1
Cyclin fold protein 1
cyclin-X

Gene names

Name:	CCNY
Synonyms:	C10orf9, CBCP1, CFP1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. Ref.1 Ref.2 Ref.14 Ref.18
Subunit structure	Interacts with CDK14, CDK16 and LRP6. Ref.1 Ref.14 Ref.18
Subcellular location	Cell membrane; Lipid-anchor; Cytoplasmic side Ref.1 Ref.2 Ref.14 Ref.18. Isoform 3: Nucleus Ref.1 Ref.2 Ref.14 Ref.18.
Tissue specificity	Widely expressed. Ref.2
Developmental stage	Enriched at G2/M. Ref.14
Post-translational modification	Ubiquitinated; leading to its degradation. Ref.14
Sequence similarities	Belongs to the cyclin family. Cyclin Y subfamily. Contains 1 cyclin N-terminal domain.
Sequence caution	The sequence AAH69224.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Cell cycle Cell division Wnt signaling pathway
Cellular component	Cell membrane Membrane Nucleus
Coding sequence diversity	Alternative splicing
Molecular function	Cyclin
PTM	Lipoprotein Myristate Phosphoprotein Ubl conjugation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G2/M transition of mitotic cell cycle Inferred from direct assay Ref.14. Source: UniProtKB Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW positive regulation of cyclin-dependent protein kinase activity Inferred from direct assay Ref.1Ref.14. Source: UniProtKB regulation of canonical Wnt receptor signaling pathway Inferred from direct assay Ref.14. Source: UniProtKB
Cellular_component	cytoplasmic cyclin-dependent protein kinase holoenzyme complex Inferred from direct assay Ref.1Ref.14. Source: UniProtKB nucleus Inferred from direct assay. Source: LIFEdb plasma membrane Inferred from direct assay Ref.1Ref.14. Source: UniProtKB
Molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity Inferred from direct assay Ref.1Ref.14. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8ND76-1)

Also known as: b;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8ND76-2)

Also known as: a;

The sequence of this isoform differs from the canonical sequence as follows:
     52-76: Missing.

Isoform 3 (identifier: Q8ND76-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-54: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Cyclin-Y		PRO_0000080514
Regions
	Domain	143 – 265	123	Cyclin N-terminal
Amino acid modifications
	Modified residue	21	1	Phosphoserine By similarity
	Modified residue	25	1	Phosphoserine Ref.13
	Modified residue	83	1	Phosphoserine By similarity
	Modified residue	102	1	Phosphoserine By similarity
	Modified residue	324	1	Phosphoserine By similarity
	Modified residue	326	1	Phosphoserine Ref.17 Ref.18
	Lipidation	2	1	N-myristoyl glycine Ref.1 Ref.14
Natural variations
	Alternative sequence	1 – 54	54	Missing in isoform 3.		VSP_014833
	Alternative sequence	52 – 76	25	Missing in isoform 2.		VSP_014834
Experimental info
	Mutagenesis	2	1	G → A: Induces a diffuse cytoplasmic localization. Ref.1 Ref.14
	Mutagenesis	3	1	N → A: No effect on subcellular location. Ref.1
	Sequence conflict	78	1	R → G in AAL78998. Ref.4
	Sequence conflict	118	1	Y → H in AAL78999. Ref.4
	Sequence conflict	155	1	S → C in AAS79427. Ref.1
	Sequence conflict	155	1	S → C in AAL07802. Ref.3
	Sequence conflict	171	1	I → M in AAS79427. Ref.1
	Sequence conflict	171	1	I → M in AAL07802. Ref.3
	Sequence conflict	190	1	I → V in BAB71409. Ref.5
	Sequence conflict	216	1	V → A in AAS79427. Ref.1
	Sequence conflict	216	1	V → A in AAL07802. Ref.3
	Sequence conflict	250	1	N → S in BAB71409. Ref.5
	Sequence conflict	268	1	S → F in AAS79427. Ref.1
	Sequence conflict	268	1	S → F in AAL07802. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (b) [UniParc]. Last modified September 13, 2004. Version 2. Checksum: 949FDE1EE45C2C6E	FASTA	341	39,337
	10 20 30 40 50 60 MGNTTSCCVS SSPKLRRNAH SRLESYRPDT DLSREDTGCN LQHISDRENI DDLNMEFNPS 70 80 90 100 110 120 DHPRASTIFL SKSQTDVREK RKSLFINHHP PGQIARKYSS CSTIFLDDST VSQPNLKYTI 130 140 150 160 170 180 KCVALAIYYH IKNRDPDGRM LLDIFDENLH PLSKSEVPPD YDKHNPEQKQ IYRFVRTLFS 190 200 210 220 230 240 AAQLTAECAI VTLVYLERLL TYAEIDICPA NWKRIVLGAI LLASKVWDDQ AVWNVDYCQI 250 260 270 280 290 300 LKDITVEDMN ELERQFLELL QFNINVPSSV YAKYYFDLRS LAEANNLSFP LEPLSRERAH 310 320 330 340 KLEAISRLCE DKYKDLRRSA RKRSASADNL TLPRWSPAII S
	Isoform 2 (a) [UniParc]. Checksum: D9DC97553928235E	FASTA	316	36,504
	10 20 30 40 50 60 MGNTTSCCVS SSPKLRRNAH SRLESYRPDT DLSREDTGCN LQHISDRENI DVREKRKSLF 70 80 90 100 110 120 INHHPPGQIA RKYSSCSTIF LDDSTVSQPN LKYTIKCVAL AIYYHIKNRD PDGRMLLDIF 130 140 150 160 170 180 DENLHPLSKS EVPPDYDKHN PEQKQIYRFV RTLFSAAQLT AECAIVTLVY LERLLTYAEI 190 200 210 220 230 240 DICPANWKRI VLGAILLASK VWDDQAVWNV DYCQILKDIT VEDMNELERQ FLELLQFNIN 250 260 270 280 290 300 VPSSVYAKYY FDLRSLAEAN NLSFPLEPLS RERAHKLEAI SRLCEDKYKD LRRSARKRSA 310 SADNLTLPRW SPAIIS
	Isoform 3 [UniParc]. Checksum: 88D15913BF680A01	FASTA	287	33,245
	10 20 30 40 50 60 MEFNPSDHPR ASTIFLSKSQ TDVREKRKSL FINHHPPGQI ARKYSSCSTI FLDDSTVSQP 70 80 90 100 110 120 NLKYTIKCVA LAIYYHIKNR DPDGRMLLDI FDENLHPLSK SEVPPDYDKH NPEQKQIYRF 130 140 150 160 170 180 VRTLFSAAQL TAECAIVTLV YLERLLTYAE IDICPANWKR IVLGAILLAS KVWDDQAVWN 190 200 210 220 230 240 VDYCQILKDI TVEDMNELER QFLELLQFNI NVPSSVYAKY YFDLRSLAEA NNLSFPLEPL 250 260 270 280 SRERAHKLEA ISRLCEDKYK DLRRSARKRS ASADNLTLPR WSPAIIS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1." Jiang M., Gao Y., Yang T., Zhu X., Chen J. FEBS Lett. 583:2171-2178(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CDK14, MYRISTOYLATION AT GLY-2, MUTAGENESIS OF GLY-2 AND ASN-3.
[2]	"Identification and characterization of cyclin X which activates transcriptional activities of c-Myc." Li X., Wang X., Liu G., Li R., Yu L. Mol. Biol. Rep. 36:97-103(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Testis.
[3]	"Identification and characterization of CBCP1, a novel gene located on human chromosome 10." Gong L., Wu K. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[4]	"Human cyclin fold protein 1." Shannon M. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Testis.
[6]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Brain.
[7]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[9]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3). Tissue: Brain, Cerebellum, Neuroblastoma and Testis.
[10]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
[11]	"Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment." Carrascal M., Ovelleiro D., Casas V., Gay M., Abian J. J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: T-cell.
[12]	"Phosphoproteome of resting human platelets." Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J., Schuetz C., Walter U., Gambaryan S., Sickmann A. J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Platelet.
[13]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[14]	"Cell cycle control of wnt receptor activation." Davidson G., Shen J., Huang Y.L., Su Y., Karaulanov E., Bartscherer K., Hassler C., Stannek P., Boutros M., Niehrs C. Dev. Cell 17:788-799(2009) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, INTERACTION WITH CDK14 AND LRP6, UBIQUITINATION, MYRISTOYLATION AT GLY-2, MUTAGENESIS OF GLY-2.
[15]	"Large-scale proteomics analysis of the human kinome." Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H. Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[16]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
[17]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-326, MASS SPECTROMETRY.
[18]	"Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis." Mikolcevic P., Sigl R., Rauch V., Hess M.W., Pfaller K., Barisic M., Pelliniemi L.J., Boesl M., Geley S. Mol. Cell. Biol. 32:868-879(2012) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CDK16, PHOSPHORYLATION AT SER-326.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY504868 mRNA. Translation: AAS79427.1. AF429969 mRNA. Translation: AAP97301.1. AF413522 mRNA. Translation: AAL07802.1. AF465728 mRNA. Translation: AAL78998.1. AF465729 mRNA. Translation: AAL78999.1. AK057280 mRNA. Translation: BAB71409.1. AL834355 mRNA. Translation: CAD39020.2. AL592445, AL121749, AL603824 Genomic DNA. Translation: CAH70072.1. AL592445 , AL121749, AL603824, AL117336 Genomic DNA. Translation: CAH70073.1. AL603824, AL121749, AL592445 Genomic DNA. Translation: CAH71567.1. AL603824 , AL121749, AL592445, AL117336 Genomic DNA. Translation: CAH71568.1. AL117336 , AL121749, AL603824, AL592445 Genomic DNA. Translation: CAH72501.1. AL121749, AL603824, AL592445 Genomic DNA. Translation: CAH73707.1. AL121749 , AL603824, AL592445, AL117336 Genomic DNA. Translation: CAH73709.1. CH471072 Genomic DNA. Translation: EAW85912.1. CH471072 Genomic DNA. Translation: EAW85913.1. CH471072 Genomic DNA. Translation: EAW85914.1. BC069224 mRNA. Translation: AAH69224.1. Different initiation. BC094815 mRNA. Translation: AAH94815.1. BC104773 mRNA. Translation: AAI04774.1. BC104801 mRNA. Translation: AAI04802.1. BC143450 mRNA. Translation: AAI43451.1. BC143455 mRNA. Translation: AAI43456.1.
IPI	IPI00334743. IPI00413625. IPI00465457.
RefSeq	NP_659449.3. NM_145012.4. NP_859049.2. NM_181698.2.
UniGene	Hs.14745. Hs.651463. Hs.714184.
3D structure databases
ProteinModelPortal	Q8ND76.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1649053.
PTM databases
PhosphoSite	Q8ND76.
Polymorphism databases
DMDM	71658801.
Proteomic databases
PaxDb	Q8ND76.
PRIDE	Q8ND76.
Protocols and materials databases
DNASU	219771.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000265375; ENSP00000265375; ENSG00000108100. ENST00000339497; ENSP00000344275; ENSG00000108100. ENST00000374704; ENSP00000363836; ENSG00000108100. ENST00000374706; ENSP00000363838; ENSG00000108100. ENST00000537547; ENSP00000439277; ENSG00000108100.
GeneID	219771.
KEGG	hsa:219771.
UCSC	uc001iyu.4. human. uc009xmb.3. human.
Organism-specific databases
CTD	219771.
GeneCards	GC10P035576.
HGNC	HGNC:23354. CCNY.
HPA	HPA036290.
MIM	612786. gene.
neXtProt	NX_Q8ND76.
PharmGKB	PA162381980.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG303674.
HOVERGEN	HBG058985.
InParanoid	Q8ND76.
OMA	YDKHDPE.
OrthoDB	EOG43JC51.
PhylomeDB	Q8ND76.
Gene expression databases
ArrayExpress	Q8ND76.
Bgee	Q8ND76.
CleanEx	HS_CCNY.
Genevestigator	Q8ND76.
GermOnline	ENSG00000108100. Homo sapiens.
Family and domain databases
Gene3D	1.10.472.10. 1 hit.
InterPro	IPR013763. Cyclin-like. IPR006671. Cyclin_N. IPR012399. Cyclin_Y. [Graphical view]
Pfam	PF00134. Cyclin_N. 1 hit. [Graphical view]
PIRSF	PIRSF028934. Cyclin_CG14939. 1 hit.
SMART	SM00385. CYCLIN. 1 hit. [Graphical view]
SUPFAM	SSF47954. Cyclin_like. 1 hit.
PROSITE	PS00292. CYCLINS. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CCNY. human.
GenomeRNAi	219771.
NextBio	90749.
SOURCE	Search...

Entry information

Entry name

CCNY_HUMAN

Accession

Primary (citable) accession number: Q8ND76
Secondary accession number(s): B7ZKX9 , D3DRY9, Q2M3V4, Q2TU96, Q6NT86, Q7Z4U7, Q8TEX2, Q8TEX3, Q96M99, Q96P45

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2005
Last sequence update:	September 13, 2004
Last modified:	May 1, 2013
This is version 106 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.