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Q8NCW4 (Q8NCW4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:KLK3 EMBL CAD30844.1
OrganismHomo sapiens (Human) EMBL CAD30844.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential EMBL CAD30844.1
Chain18 – 220203 Potential EMBL CAD30844.1
PRO_5000068520
Chain25 – 220196prostate specific antigen EMBL CAD30844.1
PRO_5000068521

Sequences

Sequence LengthMass (Da)Tools
Q8NCW4 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 15C8886A504A248D

FASTA22024,341
        10         20         30         40         50         60 
MWVPVVFLTL SVTWIGAAPL ILSRIVGGWE CEKHSQPWQV LVASRGRAVC GGVLVHPQWV 

        70         80         90        100        110        120 
LTAAHCIRNK SVILLGRHSL FHPEDTGQVF QVSHSFPHPL YDMSLLKNRF LRPGDDSSIE 

       130        140        150        160        170        180 
PEEFLTPKKL QCVDLHVISN DVCAQVHPQK VTKFMLCAGR WTGGKSTCSG DSGGPLVCNG 

       190        200        210        220 
VLQGITSWGS EPCALPERPS LYTKVVHYRK WIKDTIVANP 

« Hide

References

[1]"Complex alternative splicing of the hKLK3 gene coding for the tumour marker PSA (prostate-specific-antigen)."
Heuze-Vourc'h N., Courty Y.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Prostate EMBL CAD30844.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ459782 mRNA. Translation: CAD30844.1.
UniGeneHs.171995.

3D structure databases

ProteinModelPortalQ8NCW4.
SMRQ8NCW4. Positions 25-220.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHOG000251820.
HOVERGENHBG013304.

Family and domain databases

InterProIPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamPF00089. Trypsin. 2 hits.
[Graphical view]
PRINTSPR00722. CHYMOTRYPSIN.
SMARTSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMSSF50494. SSF50494. 1 hit.
PROSITEPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSKLK3. human.
NextBio13641002.
PMAP-CutDBQ8NCW4.

Entry information

Entry nameQ8NCW4_HUMAN
AccessionPrimary (citable) accession number: Q8NCW4
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.