Q8NCM2 (KCNH5_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Potassium voltage-gated channel subfamily H member 5

Alternative name(s):
Ether-a-go-go potassium channel 2
Short name=hEAG2
Voltage-gated potassium channel subunit Kv10.2

Gene names

Name:	KCNH5
Synonyms:	EAG2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	988 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
Subunit structure	The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH1/EAG Probable.
Subcellular location	Membrane; Multi-pass membrane protein.
Tissue specificity	Detected in brain, skeletal muscle, heart, placenta, lung and liver, and at low levels in kidney.
Domain	The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
Sequence similarities	Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily. [View classification] Contains 1 cyclic nucleotide-binding domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain.
Sequence caution	The sequence BAC11016.1 differs from that shown. Reason: Erroneous termination at position 436. Translated as Gly.

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
Ligand	Calmodulin-binding Potassium
Molecular function	Ion channel Potassium channel Voltage-gated channel
PTM	Glycoprotein Isopeptide bond Ubl conjugation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of G2/M transition of mitotic cell cycle Inferred from direct assay PubMed 22855790. Source: MGI signal transduction by phosphorylation Inferred from electronic annotation. Source: GOC synaptic transmission Traceable author statement. Source: Reactome
Cellular_component	cell surface Inferred from direct assay PubMed 22855790. Source: MGI integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW intracellular Inferred from direct assay PubMed 22855790. Source: MGI plasma membrane Traceable author statement. Source: Reactome
Molecular_function	phosphorelay sensor kinase activity Inferred from electronic annotation. Source: InterPro voltage-gated potassium channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Note: Experimental confirmation may be lacking for some isoforms.

Isoform 1 (identifier: Q8NCM2-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8NCM2-2)

Also known as: 2b;

The sequence of this isoform differs from the canonical sequence as follows:
     608-611: GKGD → DHLS
     612-988: Missing.

Isoform 3 (identifier: Q8NCM2-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-58: Missing.
     674-682: IIFRKISDV → GWFSMANAL
     683-988: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 988	988	Potassium voltage-gated channel subfamily H member 5		PRO_0000054010
Regions
	Topological domain	1 – 217	217	Cytoplasmic Potential
	Transmembrane	218 – 238	21	Helical; Name=Segment S1; Potential
	Topological domain	239 – 243	5	Extracellular Potential
	Transmembrane	244 – 264	21	Helical; Name=Segment S2; Potential
	Topological domain	265 – 291	27	Cytoplasmic Potential
	Transmembrane	292 – 312	21	Helical; Name=Segment S3; Potential
	Topological domain	313 – 319	7	Extracellular Potential
	Transmembrane	320 – 340	21	Helical; Voltage-sensor; Name=Segment S4; Potential
	Topological domain	341 – 346	6	Cytoplasmic Potential
	Transmembrane	347 – 367	21	Helical; Name=Segment S5; Potential
	Topological domain	368 – 419	52	Extracellular Potential
	Intramembrane	420 – 440	21	Pore-forming; Name=Segment H5; Potential
	Topological domain	441 – 446	6	Extracellular Potential
	Transmembrane	447 – 467	21	Helical; Name=Segment S6; Potential
	Topological domain	468 – 988	521	Cytoplasmic Potential
	Domain	12 – 90	79	PAS
	Domain	91 – 143	53	PAC
	Nucleotide binding	550 – 667	118	cNMP
	Region	704 – 715	12	Calmodulin-binding Potential
	Region	909 – 948	40	CAD (involved in subunit assembly) By similarity
	Motif	432 – 437	6	Selectivity filter By similarity
Amino acid modifications
	Glycosylation	403	1	N-linked (GlcNAc...) Potential
	Cross-link	785		Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) Ref.7
Natural variations
	Alternative sequence	1 – 58	58	Missing in isoform 3.		VSP_000972
	Alternative sequence	608 – 611	4	GKGD → DHLS in isoform 2.		VSP_000973
	Alternative sequence	612 – 988	377	Missing in isoform 2.		VSP_000974
	Alternative sequence	674 – 682	9	IIFRKISDV → GWFSMANAL in isoform 3.		VSP_000975
	Alternative sequence	683 – 988	306	Missing in isoform 3.		VSP_000976
	Natural variant	745	1	A → T. Ref.1 Ref.2 Ref.6 Corresponds to variant rs4902176 [ dbSNP | Ensembl ].		VAR_065162

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 31, 2011. Version 3. Checksum: A58E4CE0A32C83BC	FASTA	988	111,877
	10 20 30 40 50 60 MPGGKRGLVA PQNTFLENIV RRSSESSFLL GNAQIVDWPV VYSNDGFCKL SGYHRADVMQ 70 80 90 100 110 120 KSSTCSFMYG ELTDKKTIEK VRQTFDNYES NCFEVLLYKK NRTPVWFYMQ IAPIRNEHEK 130 140 150 160 170 180 VVLFLCTFKD ITLFKQPIED DSTKGWTKFA RLTRALTNSR SVLQQLTPMN KTEVVHKHSR 190 200 210 220 230 240 LAEVLQLGSD ILPQYKQEAP KTPPHIILHY CAFKTTWDWV ILILTFYTAI MVPYNVSFKT 250 260 270 280 290 300 KQNNIAWLVL DSVVDVIFLV DIVLNFHTTF VGPGGEVISD PKLIRMNYLK TWFVIDLLSC 310 320 330 340 350 360 LPYDIINAFE NVDEGISSLF SSLKVVRLLR LGRVARKLDH YLEYGAAVLV LLVCVFGLVA 370 380 390 400 410 420 HWLACIWYSI GDYEVIDEVT NTIQIDSWLY QLALSIGTPY RYNTSAGIWE GGPSKDSLYV 430 440 450 460 470 480 SSLYFTMTSL TTIGFGNIAP TTDVEKMFSV AMMMVGSLLY ATIFGNVTTI FQQMYANTNR 490 500 510 520 530 540 YHEMLNNVRD FLKLYQVPKG LSERVMDYIV STWSMSKGID TEKVLSICPK DMRADICVHL 550 560 570 580 590 600 NRKVFNEHPA FRLASDGCLR ALAVEFQTIH CAPGDLIYHA GESVDALCFV VSGSLEVIQD 610 620 630 640 650 660 DEVVAILGKG DVFGDIFWKE TTLAHACANV RALTYCDLHI IKREALLKVL DFYTAFANSF 670 680 690 700 710 720 SRNLTLTCNL RKRIIFRKIS DVKKEEEERL RQKNEVTLSI PVDHPVRKLF QKFKQQKELR 730 740 750 760 770 780 NQGSTQGDPE RNQLQVESRS LQNGASITGT SVVTVSQITP IQTSLAYVKT SESLKQNNRD 790 800 810 820 830 840 AMELKPNGGA DQKCLKVNSP IRMKNGNGKG WLRLKNNMGA HEEKKEDWNN VTKAESMGLL 850 860 870 880 890 900 SEDPKSSDSE NSVTKNPLRK TDSCDSGITK SDLRLDKAGE ARSPLEHSPI QADAKHPFYP 910 920 930 940 950 960 IPEQALQTTL QEVKHELKED IQLLSCRMTA LEKQVAEILK ILSEKSVPQA SSPKSQMPLQ 970 980 VPPQIPCQDI FSVSRPESPE SDKDEIHF
	Isoform 2 (2b) [UniParc]. Checksum: 7BFDAE4B26410886	FASTA	611	69,443
	10 20 30 40 50 60 MPGGKRGLVA PQNTFLENIV RRSSESSFLL GNAQIVDWPV VYSNDGFCKL SGYHRADVMQ 70 80 90 100 110 120 KSSTCSFMYG ELTDKKTIEK VRQTFDNYES NCFEVLLYKK NRTPVWFYMQ IAPIRNEHEK 130 140 150 160 170 180 VVLFLCTFKD ITLFKQPIED DSTKGWTKFA RLTRALTNSR SVLQQLTPMN KTEVVHKHSR 190 200 210 220 230 240 LAEVLQLGSD ILPQYKQEAP KTPPHIILHY CAFKTTWDWV ILILTFYTAI MVPYNVSFKT 250 260 270 280 290 300 KQNNIAWLVL DSVVDVIFLV DIVLNFHTTF VGPGGEVISD PKLIRMNYLK TWFVIDLLSC 310 320 330 340 350 360 LPYDIINAFE NVDEGISSLF SSLKVVRLLR LGRVARKLDH YLEYGAAVLV LLVCVFGLVA 370 380 390 400 410 420 HWLACIWYSI GDYEVIDEVT NTIQIDSWLY QLALSIGTPY RYNTSAGIWE GGPSKDSLYV 430 440 450 460 470 480 SSLYFTMTSL TTIGFGNIAP TTDVEKMFSV AMMMVGSLLY ATIFGNVTTI FQQMYANTNR 490 500 510 520 530 540 YHEMLNNVRD FLKLYQVPKG LSERVMDYIV STWSMSKGID TEKVLSICPK DMRADICVHL 550 560 570 580 590 600 NRKVFNEHPA FRLASDGCLR ALAVEFQTIH CAPGDLIYHA GESVDALCFV VSGSLEVIQD 610 DEVVAILDHL S
	Isoform 3 [UniParc]. Checksum: D6D18C16D9CAA93F	FASTA	624	71,123
	10 20 30 40 50 60 MQKSSTCSFM YGELTDKKTI EKVRQTFDNY ESNCFEVLLY KKNRTPVWFY MQIAPIRNEH 70 80 90 100 110 120 EKVVLFLCTF KDITLFKQPI EDDSTKGWTK FARLTRALTN SRSVLQQLTP MNKTEVVHKH 130 140 150 160 170 180 SRLAEVLQLG SDILPQYKQE APKTPPHIIL HYCAFKTTWD WVILILTFYT AIMVPYNVSF 190 200 210 220 230 240 KTKQNNIAWL VLDSVVDVIF LVDIVLNFHT TFVGPGGEVI SDPKLIRMNY LKTWFVIDLL 250 260 270 280 290 300 SCLPYDIINA FENVDEGISS LFSSLKVVRL LRLGRVARKL DHYLEYGAAV LVLLVCVFGL 310 320 330 340 350 360 VAHWLACIWY SIGDYEVIDE VTNTIQIDSW LYQLALSIGT PYRYNTSAGI WEGGPSKDSL 370 380 390 400 410 420 YVSSLYFTMT SLTTIGFGNI APTTDVEKMF SVAMMMVGSL LYATIFGNVT TIFQQMYANT 430 440 450 460 470 480 NRYHEMLNNV RDFLKLYQVP KGLSERVMDY IVSTWSMSKG IDTEKVLSIC PKDMRADICV 490 500 510 520 530 540 HLNRKVFNEH PAFRLASDGC LRALAVEFQT IHCAPGDLIY HAGESVDALC FVVSGSLEVI 550 560 570 580 590 600 QDDEVVAILG KGDVFGDIFW KETTLAHACA NVRALTYCDL HIIKREALLK VLDFYTAFAN 610 620 SFSRNLTLTC NLRKRGWFSM ANAL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional distinction of human EAG1 and EAG2 potassium channels." Schoenherr R., Gessner G., Loeber K., Heinemann S.H. FEBS Lett. 514:204-208(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT THR-745. Tissue: Brain.
[2]	"Molecular identification and characterisation of the human eag2 potassium channel." Ju M., Wray D. FEBS Lett. 524:204-210(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANT THR-745. Tissue: Fetal brain.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
[4]	"The DNA sequence and analysis of human chromosome 14." Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J. Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT THR-745. Tissue: PNS.
[7]	"Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells." Tan F., Lu L., Cai Y., Wang J., Xie Y., Wang L., Gong Y., Xu B.-E., Wu J., Luo Y., Qiang B., Yuan J., Sun X., Peng X. Proteomics 8:2885-2896(2008) [PubMed] [Europe PMC] [Abstract] Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-785, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF418206 mRNA. Translation: AAM28435.1. AF472412 mRNA. Translation: AAM49565.1. AF493798 mRNA. Translation: AAM49574.1. AK074484 mRNA. Translation: BAC11016.1. Sequence problems. AL109985 Genomic DNA. No translation available. AL132666 Genomic DNA. No translation available. AL137191 Genomic DNA. No translation available. AL355101 Genomic DNA. No translation available. CH471061 Genomic DNA. Translation: EAW80819.1. BC073979 mRNA. Translation: AAH73979.1.
IPI	IPI00171491. IPI00220699. IPI00220700.
RefSeq	NP_647479.2. NM_139318.3. NP_758963.1. NM_172375.1. NP_758964.1. NM_172376.1.
UniGene	Hs.27043.
3D structure databases
ProteinModelPortal	Q8NCM2.
SMR	Q8NCM2. Positions 5-129, 418-472, 481-676.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000321427.
PTM databases
PhosphoSite	Q8NCM2.
Polymorphism databases
DMDM	26006802.
Proteomic databases
PaxDb	Q8NCM2.
PRIDE	Q8NCM2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000322893; ENSP00000321427; ENSG00000140015. ENST00000394968; ENSP00000378419; ENSG00000140015. ENST00000420622; ENSP00000395439; ENSG00000140015.
GeneID	27133.
KEGG	hsa:27133.
UCSC	uc001xfx.3. human. uc001xfy.3. human. uc001xfz.1. human.
Organism-specific databases
CTD	27133.
GeneCards	GC14M063173.
HGNC	HGNC:6254. KCNH5.
HPA	HPA030487.
MIM	605716. gene.
neXtProt	NX_Q8NCM2.
PharmGKB	PA30040.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG2202.
HOGENOM	HOG000230794.
HOVERGEN	HBG101348.
InParanoid	Q8NCM2.
KO	K04908.
OMA	PKCLKVN.
OrthoDB	EOG47PX5C.
PhylomeDB	Q8NCM2.
Enzyme and pathway databases
Reactome	REACT_13685. Neuronal System.
Gene expression databases
ArrayExpress	Q8NCM2.
Bgee	Q8NCM2.
CleanEx	HS_KCNH5.
Genevestigator	Q8NCM2.
GermOnline	ENSG00000140015. Homo sapiens.
Family and domain databases
Gene3D	2.60.120.10. 1 hit.
InterPro	IPR018490. cNMP-bd-like. IPR000595. cNMP-bd_dom. IPR005821. Ion_trans_dom. IPR003949. K_chnl_volt-dep_EAG. IPR003938. K_chnl_volt-dep_EAG/ELK/ERG. IPR001610. PAC. IPR000014. PAS. IPR000700. PAS-assoc_C. IPR014710. RmlC-like_jellyroll. [Graphical view]
Pfam	PF00027. cNMP_binding. 1 hit. PF00520. Ion_trans. 1 hit. [Graphical view]
PRINTS	PR01463. EAGCHANLFMLY. PR01464. EAGCHANNEL.
SMART	SM00100. cNMP. 1 hit. SM00086. PAC. 1 hit. SM00091. PAS. 1 hit. [Graphical view]
SUPFAM	SSF51206. cNMP_binding. 1 hit. SSF55785. SSF55785. 1 hit.
TIGRFAMs	TIGR00229. sensory_box. 1 hit.
PROSITE	PS00888. CNMP_BINDING_1. False negative. PS00889. CNMP_BINDING_2. False negative. PS50042. CNMP_BINDING_3. 1 hit. PS50113. PAC. 1 hit. PS50112. PAS. False negative. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	27133.
NextBio	49870.
SOURCE	Search...

Entry information

Entry name

KCNH5_HUMAN

Accession

Primary (citable) accession number: Q8NCM2
Secondary accession number(s): C9JP98

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2002
Last sequence update:	May 31, 2011
Last modified:	May 29, 2013
This is version 112 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.