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Reviewed, UniProtKB/Swiss-Prot Q8NC74 (CT151_HUMAN)

Last modified November 24, 2009. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Uncharacterized protein C20orf151
Gene names
Name: C20orf151
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length664 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 664664Uncharacterized protein C20orf151
PRO_0000079470

Regions

Compositional bias475 – 56086Pro-rich

Natural variations

Natural variant3481D → N: dbSNP rs3810553. Ref.3
VAR_056849
Natural variant4081A → T: dbSNP rs10888228.
VAR_056850
Natural variant6071E → K: dbSNP rs6089366.
VAR_056851
Natural variant6371L → R: dbSNP rs2236200. Ref.3
VAR_056852

Experimental info

Sequence conflict1271G → V in BAC11293. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q8NC74-1 [UniParc].

Last modified March 1, 2005. Version 3.
Checksum: AF74AE9E54CE88F8

FASTA66471,432
        10         20         30         40         50         60 
MESFMESLNR LKEIHEKEVL GLQNKLLELN SERCRDAQRI EELFSKNHQL REQQKTLKEN 

        70         80         90        100        110        120 
LRVLENRLRA GLCDRCMVTQ ELARKRQQEF ESSHLQNLQR IFILTNEMNG LKEENETLKE 

       130        140        150        160        170        180 
EVKRLRGLGD RPKPRAKEGT SDPPSPLLLP SPGGWKAITE KPPGGHEEAE EDHQGVGLRG 

       190        200        210        220        230        240 
EEKPAGHRTS PVAKISPGAT LPESRAPDMS PQRISNQLHG TIAVVRPGSQ ACPADRGPAN 

       250        260        270        280        290        300 
GTPPPLPARS SPPSPAYERG LSLDSFLRAS RPSAMTHEAP KLSPKVDRLC LLNRPLSLHL 

       310        320        330        340        350        360 
QSPHSSPLAP AAAPSDPRLQ DLKAREAEAW EEPTELLGLP SALAGMQDLR LEGALHLLLA 

       370        380        390        400        410        420 
QQQLRARARA GSVRPRGQPT PGEMLPSLPV GSDSEGPENE GTRAALAAAG LSGGRHTQPA 

       430        440        450        460        470        480 
GPGRAQRTEA AATQDCALDK PLDLSEWGRA RGQDTPKPAG QHGSLSPAAA HTASPEPPTQ 

       490        500        510        520        530        540 
SGPLTRSPQA LSNGTKGTRV PEQEEASTPM DPSRPLPGSQ LSLSSPGSTE DEDTGRPLPP 

       550        560        570        580        590        600 
PHPQPPPHPQ PPDLDGHPEP SKAEVLRPES DELDETDTPG SEVGLSSQAE ATTSTTGEGP 

       610        620        630        640        650        660 
ECICTQEHGQ GPPRKRKRAS EPGDKASKKP SRGRRKLTAT EGPGSPRDAE DHSPSPNSSP 


WEET 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Teratocarcinoma.
[2]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed: 11780052] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ASN-348 AND ARG-637.
Tissue: Placenta.

Cross-references

Sequence databases

AK074919 mRNA. Translation: BAC11293.1.
AL121832 Genomic DNA. Translation: CAI23285.1.
BC006450 mRNA. Translation: AAH06450.1.
BC033142 mRNA. Translation: AAH33142.2.
BC137326 mRNA. Translation: AAI37327.1.
BC137327 mRNA. Translation: AAI37328.1.
IPIIPI00168344.
RefSeqNP_543023.1.
UniGeneHs.180374

3D structure databases

ModBaseSearch...

PTM databases

PhosphoSiteQ8NC74.

Proteomic databases

PRIDEQ8NC74.

Genome annotation databases

EnsemblENST00000252998; ENSP00000252998; ENSG00000130701; Homo sapiens. [Genome view]
GeneID140893.
KEGGhsa:140893.
NMPDRfig|9606.3.peg.20628.
UCSCuc002ycw.1. human.

Organism-specific databases

CTD140893.
GeneCardsGC20M060418.
HGNCHGNC:16144. C20orf151.
PharmGKBPA25693.
GenAtlasSearch...

Phylogenomic databases

HOGENOMQ8NC74.
HOVERGENQ8NC74.
OMAAPDMSPQ
OrthoDBEOG96HJX4

Gene expression databases

ArrayExpressQ8NC74.
BgeeQ8NC74.
CleanExHS_C20orf151.
GenevestigatorQ8NC74.
GermOnlineENSG00000130701. Homo sapiens.

Family and domain databases

InterProIPR019518. CtIP_N.
[Graphical view]
PfamPF10482. CtIP_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio84555.

Entry information

Entry nameCT151_HUMAN
AccessionPrimary (citable) accession number: Q8NC74
Secondary accession number(s): B2RP98 expand/collapse secondary AC list , Q8N4Z9, Q9BR75, Q9H0Y9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: March 1, 2005
Last modified: November 24, 2009
This is version 57 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents