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Protein

RBBP8 N-terminal-like protein

Gene

RBBP8NL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
RBBP8 N-terminal-like protein
Gene namesi
Name:RBBP8NL
Synonyms:C20orf151
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000130701.3
HGNCiHGNC:16144 RBBP8NL
neXtProtiNX_Q8NC74

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130701
PharmGKBiPA25693

Polymorphism and mutation databases

BioMutaiRBBP8NL
DMDMi60416376

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000794701 – 664RBBP8 N-terminal-like proteinAdd BLAST664

Proteomic databases

MaxQBiQ8NC74
PaxDbiQ8NC74
PeptideAtlasiQ8NC74
PRIDEiQ8NC74

PTM databases

iPTMnetiQ8NC74
PhosphoSitePlusiQ8NC74

Expressioni

Gene expression databases

BgeeiENSG00000130701
CleanExiHS_C20orf151
GenevisibleiQ8NC74 HS

Organism-specific databases

HPAiHPA042627

Interactioni

Protein-protein interaction databases

IntActiQ8NC74, 10 interactors
MINTiQ8NC74
STRINGi9606.ENSP00000252998

Structurei

3D structure databases

ProteinModelPortaliQ8NC74
SMRiQ8NC74
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi475 – 560Pro-richAdd BLAST86

Phylogenomic databases

eggNOGiENOG410IKHR Eukaryota
ENOG410YF09 LUCA
GeneTreeiENSGT00530000063835
HOGENOMiHOG000231237
HOVERGENiHBG051201
InParanoidiQ8NC74
OMAiAPDMSPQ
OrthoDBiEOG091G0QP3
PhylomeDBiQ8NC74
TreeFamiTF336239

Family and domain databases

InterProiView protein in InterPro
IPR019518 CtIP_N
IPR033316 RBBP8-like
PANTHERiPTHR15107 PTHR15107, 1 hit
PfamiView protein in Pfam
PF10482 CtIP_N, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NC74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESFMESLNR LKEIHEKEVL GLQNKLLELN SERCRDAQRI EELFSKNHQL
60 70 80 90 100
REQQKTLKEN LRVLENRLRA GLCDRCMVTQ ELARKRQQEF ESSHLQNLQR
110 120 130 140 150
IFILTNEMNG LKEENETLKE EVKRLRGLGD RPKPRAKEGT SDPPSPLLLP
160 170 180 190 200
SPGGWKAITE KPPGGHEEAE EDHQGVGLRG EEKPAGHRTS PVAKISPGAT
210 220 230 240 250
LPESRAPDMS PQRISNQLHG TIAVVRPGSQ ACPADRGPAN GTPPPLPARS
260 270 280 290 300
SPPSPAYERG LSLDSFLRAS RPSAMTHEAP KLSPKVDRLC LLNRPLSLHL
310 320 330 340 350
QSPHSSPLAP AAAPSDPRLQ DLKAREAEAW EEPTELLGLP SALAGMQDLR
360 370 380 390 400
LEGALHLLLA QQQLRARARA GSVRPRGQPT PGEMLPSLPV GSDSEGPENE
410 420 430 440 450
GTRAALAAAG LSGGRHTQPA GPGRAQRTEA AATQDCALDK PLDLSEWGRA
460 470 480 490 500
RGQDTPKPAG QHGSLSPAAA HTASPEPPTQ SGPLTRSPQA LSNGTKGTRV
510 520 530 540 550
PEQEEASTPM DPSRPLPGSQ LSLSSPGSTE DEDTGRPLPP PHPQPPPHPQ
560 570 580 590 600
PPDLDGHPEP SKAEVLRPES DELDETDTPG SEVGLSSQAE ATTSTTGEGP
610 620 630 640 650
ECICTQEHGQ GPPRKRKRAS EPGDKASKKP SRGRRKLTAT EGPGSPRDAE
660
DHSPSPNSSP WEET
Length:664
Mass (Da):71,432
Last modified:March 1, 2005 - v3
Checksum:iAF74AE9E54CE88F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti127G → V in BAC11293 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_056849348D → N1 PublicationCorresponds to variant dbSNP:rs3810553Ensembl.1
Natural variantiVAR_056850408A → T. Corresponds to variant dbSNP:rs10888228Ensembl.1
Natural variantiVAR_056851607E → K. Corresponds to variant dbSNP:rs6089366Ensembl.1
Natural variantiVAR_056852637L → R1 PublicationCorresponds to variant dbSNP:rs2236200Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK074919 mRNA Translation: BAC11293.1
AL121832 Genomic DNA No translation available.
BC006450 mRNA Translation: AAH06450.1
BC033142 mRNA Translation: AAH33142.2
BC137326 mRNA Translation: AAI37327.1
BC137327 mRNA Translation: AAI37328.1
CCDSiCCDS13498.1
RefSeqiNP_543023.2, NM_080833.2
UniGeneiHs.180374

Genome annotation databases

EnsembliENST00000252998; ENSP00000252998; ENSG00000130701
GeneIDi140893
KEGGihsa:140893
UCSCiuc002ycw.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiRB8NL_HUMAN
AccessioniPrimary (citable) accession number: Q8NC74
Secondary accession number(s): B2RP98
, Q8N4Z9, Q9BR75, Q9H0Y9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: March 1, 2005
Last modified: February 28, 2018
This is version 113 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health