Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8NC69

- KCTD6_HUMAN

UniProt

Q8NC69 - KCTD6_HUMAN

Protein

BTB/POZ domain-containing protein KCTD6

Gene

KCTD6

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 2 (03 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. ankyrin binding Source: MGI

    GO - Biological processi

    1. protein homooligomerization Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    BTB/POZ domain-containing protein KCTD6
    Gene namesi
    Name:KCTD6
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:22235. KCTD6.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134918095.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237BTB/POZ domain-containing protein KCTD6PRO_0000251248Add
    BLAST

    Proteomic databases

    MaxQBiQ8NC69.
    PaxDbiQ8NC69.
    PRIDEiQ8NC69.

    PTM databases

    PhosphoSiteiQ8NC69.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8NC69.
    BgeeiQ8NC69.
    CleanExiHS_KCTD6.
    GenevestigatoriQ8NC69.

    Organism-specific databases

    HPAiHPA036100.
    HPA036101.

    Interactioni

    Protein-protein interaction databases

    BioGridi128350. 7 interactions.
    IntActiQ8NC69. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NC69.
    SMRiQ8NC69. Positions 14-107.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini12 – 8170BTBAdd
    BLAST

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.Curated

    Phylogenomic databases

    eggNOGiNOG256004.
    HOGENOMiHOG000236287.
    HOVERGENiHBG080695.
    InParanoidiQ8NC69.
    OMAiDNGDWGH.
    OrthoDBiEOG7M6D81.
    PhylomeDBiQ8NC69.
    TreeFamiTF315332.

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR003131. T1-type_BTB.
    [Graphical view]
    PfamiPF02214. BTB_2. 1 hit.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8NC69-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDNGDWGYMM TDPVTLNVGG HLYTTSLTTL TRYPDSMLGA MFGGDFPTAR    50
    DPQGNYFIDR DGPLFRYVLN FLRTSELTLP LDFKEFDLLR KEADFYQIEP 100
    LIQCLNDPKP LYPMDTFEEV VELSSTRKLS KYSNPVAVII TQLTITTKVH 150
    SLLEGISNYF TKWNKHMMDT RDCQVSFTFG PCDYHQEVSL RVHLMEYITK 200
    QGFTIRNTRV HHMSERANEN TVEHNWTFCR LARKTDD 237
    Length:237
    Mass (Da):27,610
    Last modified:October 3, 2006 - v2
    Checksum:i6358D9993DD060ED
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti49 – 491A → T in BAC11531. (PubMed:16303743)Curated
    Sequence conflicti59 – 591D → N in BAC11531. (PubMed:16303743)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK027572 mRNA. Translation: BAG51347.1.
    AK074934 mRNA. Translation: BAC11301.1.
    AK075297 mRNA. Translation: BAC11531.1.
    CH471055 Genomic DNA. Translation: EAW65374.1.
    BC022893 mRNA. Translation: AAH22893.2.
    CCDSiCCDS2891.1.
    RefSeqiNP_001121686.1. NM_001128214.1.
    NP_699162.3. NM_153331.3.
    XP_005264994.1. XM_005264937.1.
    XP_006713077.1. XM_006713014.1.
    UniGeneiHs.13982.

    Genome annotation databases

    EnsembliENST00000355076; ENSP00000347188; ENSG00000168301.
    ENST00000404589; ENSP00000384948; ENSG00000168301.
    ENST00000490264; ENSP00000417490; ENSG00000168301.
    GeneIDi200845.
    KEGGihsa:200845.
    UCSCiuc003dkj.4. human.

    Polymorphism databases

    DMDMi115502243.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK027572 mRNA. Translation: BAG51347.1 .
    AK074934 mRNA. Translation: BAC11301.1 .
    AK075297 mRNA. Translation: BAC11531.1 .
    CH471055 Genomic DNA. Translation: EAW65374.1 .
    BC022893 mRNA. Translation: AAH22893.2 .
    CCDSi CCDS2891.1.
    RefSeqi NP_001121686.1. NM_001128214.1.
    NP_699162.3. NM_153331.3.
    XP_005264994.1. XM_005264937.1.
    XP_006713077.1. XM_006713014.1.
    UniGenei Hs.13982.

    3D structure databases

    ProteinModelPortali Q8NC69.
    SMRi Q8NC69. Positions 14-107.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 128350. 7 interactions.
    IntActi Q8NC69. 1 interaction.

    PTM databases

    PhosphoSitei Q8NC69.

    Polymorphism databases

    DMDMi 115502243.

    Proteomic databases

    MaxQBi Q8NC69.
    PaxDbi Q8NC69.
    PRIDEi Q8NC69.

    Protocols and materials databases

    DNASUi 200845.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000355076 ; ENSP00000347188 ; ENSG00000168301 .
    ENST00000404589 ; ENSP00000384948 ; ENSG00000168301 .
    ENST00000490264 ; ENSP00000417490 ; ENSG00000168301 .
    GeneIDi 200845.
    KEGGi hsa:200845.
    UCSCi uc003dkj.4. human.

    Organism-specific databases

    CTDi 200845.
    GeneCardsi GC03P058452.
    HGNCi HGNC:22235. KCTD6.
    HPAi HPA036100.
    HPA036101.
    neXtProti NX_Q8NC69.
    PharmGKBi PA134918095.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG256004.
    HOGENOMi HOG000236287.
    HOVERGENi HBG080695.
    InParanoidi Q8NC69.
    OMAi DNGDWGH.
    OrthoDBi EOG7M6D81.
    PhylomeDBi Q8NC69.
    TreeFami TF315332.

    Miscellaneous databases

    GenomeRNAii 200845.
    NextBioi 89985.
    PROi Q8NC69.

    Gene expression databases

    ArrayExpressi Q8NC69.
    Bgeei Q8NC69.
    CleanExi HS_KCTD6.
    Genevestigatori Q8NC69.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR003131. T1-type_BTB.
    [Graphical view ]
    Pfami PF02214. BTB_2. 1 hit.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.
      , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
      DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Lung.

    Entry informationi

    Entry nameiKCTD6_HUMAN
    AccessioniPrimary (citable) accession number: Q8NC69
    Secondary accession number(s): B3KNI5, Q8NBS6, Q8TCA6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 3, 2006
    Last sequence update: October 3, 2006
    Last modified: October 1, 2014
    This is version 84 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3