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Protein

Putative protein GATS

Gene

GATS

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein GATS
Alternative name(s):
STAG3 opposite strand transcript protein
Gene namesi
Name:GATS
Synonyms:STAG3OS
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:29954. GATS.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164720213.

Polymorphism and mutation databases

BioMutaiGATS.
DMDMi74729973.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Putative protein GATSPRO_0000325892Add
BLAST

Proteomic databases

PaxDbiQ8NAP1.
PRIDEiQ8NAP1.

PTM databases

iPTMnetiQ8NAP1.

Expressioni

Gene expression databases

ExpressionAtlasiQ8NAP1. baseline and differential.
GenevisibleiQ8NAP1. HS.

Organism-specific databases

HPAiHPA043176.

Interactioni

Protein-protein interaction databases

BioGridi131583. 3 interactions.
IntActiQ8NAP1. 2 interactions.
STRINGi9606.ENSP00000389760.

Structurei

3D structure databases

ProteinModelPortaliQ8NAP1.
SMRiQ8NAP1. Positions 48-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GATS family.Curated

Phylogenomic databases

eggNOGiENOG410IJ9B. Eukaryota.
ENOG4111D5N. LUCA.
GeneTreeiENSGT00390000006208.
InParanoidiQ8NAP1.
OMAiSEFTILW.
PhylomeDBiQ8NAP1.

Family and domain databases

InterProiIPR026249. GATS-like.
IPR027795. GATS-like_ACT_dom.
[Graphical view]
PfamiPF13840. ACT_7. 1 hit.
[Graphical view]
PRINTSiPR02078. GATSLIKEFMLY.

Sequencei

Sequence statusi: Complete.

Q8NAP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCRGRGAGG RWNSTSWSTG CKLPASPRRV SRCSPTGLIK LAFLFSKTRC
60 70 80 90 100
KFFSLTETPE DYTIIVDEEG FLELPSSEHL SVADATWLAL NVVSGGGSFS
110 120 130 140 150
SSQPIGMTKI AKSVIAPLAD QNISVFMLST YQTDFILVLK RDLPFVTHTL
160
SSEFTILWSV ARL
Length:163
Mass (Da):17,846
Last modified:October 1, 2002 - v1
Checksum:iB9BDF3D07A30E637
GO

Sequence cautioni

The sequence AAH33723.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAH53367.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAH65200.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti78 – 781E → G in AAH44886 (PubMed:15489334).Curated
Sequence conflicti82 – 821V → A in CAH18327 (PubMed:17974005).Curated
Sequence conflicti90 – 901L → P in CAH18327 (PubMed:17974005).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092358 mRNA. Translation: BAC03870.1.
AK290039 mRNA. Translation: BAF82728.1.
AK290237 mRNA. Translation: BAF82926.1.
AK290510 mRNA. Translation: BAF83199.1.
CR749506 mRNA. Translation: CAH18327.1.
CH471091 Genomic DNA. Translation: EAW76563.1.
CH471091 Genomic DNA. Translation: EAW76564.1.
CH471091 Genomic DNA. Translation: EAW76565.1.
BC033723 mRNA. Translation: AAH33723.1. Different initiation.
BC044886 mRNA. Translation: AAH44886.2.
BC053367 mRNA. Translation: AAH53367.1. Different initiation.
BC065200 mRNA. Translation: AAH65200.1. Different initiation.
BC090867 mRNA. Translation: AAH90867.1.
CCDSiCCDS43621.1.
RefSeqiNP_849153.3. NM_178831.6.
UniGeneiHs.556063.

Genome annotation databases

EnsembliENST00000328453; ENSP00000482429; ENSG00000239521.
ENST00000414739; ENSP00000479781; ENSG00000239521.
ENST00000435519; ENSP00000479420; ENSG00000239521.
ENST00000436886; ENSP00000389760; ENSG00000239521.
ENST00000543273; ENSP00000481377; ENSG00000239521.
GeneIDi352954.
KEGGihsa:352954.
UCSCiuc003uua.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092358 mRNA. Translation: BAC03870.1.
AK290039 mRNA. Translation: BAF82728.1.
AK290237 mRNA. Translation: BAF82926.1.
AK290510 mRNA. Translation: BAF83199.1.
CR749506 mRNA. Translation: CAH18327.1.
CH471091 Genomic DNA. Translation: EAW76563.1.
CH471091 Genomic DNA. Translation: EAW76564.1.
CH471091 Genomic DNA. Translation: EAW76565.1.
BC033723 mRNA. Translation: AAH33723.1. Different initiation.
BC044886 mRNA. Translation: AAH44886.2.
BC053367 mRNA. Translation: AAH53367.1. Different initiation.
BC065200 mRNA. Translation: AAH65200.1. Different initiation.
BC090867 mRNA. Translation: AAH90867.1.
CCDSiCCDS43621.1.
RefSeqiNP_849153.3. NM_178831.6.
UniGeneiHs.556063.

3D structure databases

ProteinModelPortaliQ8NAP1.
SMRiQ8NAP1. Positions 48-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131583. 3 interactions.
IntActiQ8NAP1. 2 interactions.
STRINGi9606.ENSP00000389760.

PTM databases

iPTMnetiQ8NAP1.

Polymorphism and mutation databases

BioMutaiGATS.
DMDMi74729973.

Proteomic databases

PaxDbiQ8NAP1.
PRIDEiQ8NAP1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000328453; ENSP00000482429; ENSG00000239521.
ENST00000414739; ENSP00000479781; ENSG00000239521.
ENST00000435519; ENSP00000479420; ENSG00000239521.
ENST00000436886; ENSP00000389760; ENSG00000239521.
ENST00000543273; ENSP00000481377; ENSG00000239521.
GeneIDi352954.
KEGGihsa:352954.
UCSCiuc003uua.5. human.

Organism-specific databases

CTDi352954.
GeneCardsiGATS.
HGNCiHGNC:29954. GATS.
HPAiHPA043176.
neXtProtiNX_Q8NAP1.
PharmGKBiPA164720213.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJ9B. Eukaryota.
ENOG4111D5N. LUCA.
GeneTreeiENSGT00390000006208.
InParanoidiQ8NAP1.
OMAiSEFTILW.
PhylomeDBiQ8NAP1.

Miscellaneous databases

ChiTaRSiGATS. human.
GenomeRNAii352954.

Gene expression databases

ExpressionAtlasiQ8NAP1. baseline and differential.
GenevisibleiQ8NAP1. HS.

Family and domain databases

InterProiIPR026249. GATS-like.
IPR027795. GATS-like_ACT_dom.
[Graphical view]
PfamiPF13840. ACT_7. 1 hit.
[Graphical view]
PRINTSiPR02078. GATSLIKEFMLY.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain, Hippocampus and Thalamus.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Cerebellum.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain, Eye, PNS and Uterus.

Entry informationi

Entry nameiGATS_HUMAN
AccessioniPrimary (citable) accession number: Q8NAP1
Secondary accession number(s): D6W5V0
, Q68D93, Q6P198, Q6PII7, Q7Z720, Q86UK9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Product of a dubious CDS prediction. The transcript contains several 3' non-coding exons. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.