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Q8NAC3

- I17RC_HUMAN

UniProt

Q8NAC3 - I17RC_HUMAN

Protein

Interleukin-17 receptor C

Gene

IL17RC

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • Format
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 2 (05 May 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. interleukin-17 receptor activity Source: MGI

    GO - Biological processi

    1. cytokine-mediated signaling pathway Source: GOC
    2. positive regulation of cytokine production involved in inflammatory response Source: Ensembl

    Keywords - Molecular functioni

    Receptor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Interleukin-17 receptor C
    Short name:
    IL-17 receptor C
    Short name:
    IL-17RC
    Alternative name(s):
    Interleukin-17 receptor homolog
    Short name:
    IL17Rhom
    Interleukin-17 receptor-like protein
    Short name:
    IL-17RL
    ZcytoR14
    Gene namesi
    Name:IL17RC
    ORF Names:UNQ6118/PRO20040/PRO38901
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:18358. IL17RC.

    Subcellular locationi

    Cell membrane; Single-pass type I membrane protein
    Note: Soluble isoforms may be produced.

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134986616.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 20201 PublicationAdd
    BLAST
    Chaini21 – 791771Interleukin-17 receptor CPRO_0000011034Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi189 – 1891N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi257 – 2571N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi284 – 2841N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi297 – 2971N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi324 – 3241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi334 – 3341N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi420 – 4201N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi443 – 4431N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi477 – 4771N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8NAC3.
    PRIDEiQ8NAC3.

    PTM databases

    PhosphoSiteiQ8NAC3.

    Expressioni

    Tissue specificityi

    Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta.1 Publication

    Inductioni

    By HGF and VEGF.1 Publication

    Gene expression databases

    ArrayExpressiQ8NAC3.
    BgeeiQ8NAC3.
    CleanExiHS_IL17RC.
    GenevestigatoriQ8NAC3.

    Organism-specific databases

    HPAiCAB026255.
    HPA019885.

    Interactioni

    Protein-protein interaction databases

    BioGridi124278. 1 interaction.
    STRINGi9606.ENSP00000295981.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NAC3.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini21 – 538518ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini560 – 791232CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei539 – 55921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini583 – 735153SEFIRPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SEFIR domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG45936.
    HOGENOMiHOG000112986.
    HOVERGENiHBG081776.
    InParanoidiQ8NAC3.
    KOiK05166.
    OMAiGQCLQLW.
    OrthoDBiEOG7J4466.
    PhylomeDBiQ8NAC3.
    TreeFamiTF335852.

    Family and domain databases

    InterProiIPR027841. IL-17_rcpt_C/E_N.
    IPR013568. SEFIR.
    [Graphical view]
    PfamiPF15037. IL17_R_N. 1 hit.
    PF08357. SEFIR. 1 hit.
    [Graphical view]
    PROSITEiPS51534. SEFIR. 1 hit.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Note: Additional isoforms seem to exist.

    Isoform 1 (identifier: Q8NAC3-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPVPWFLLSL ALGRSPVVLS LERLVGPQDA THCSPVSLEP WGDEERLRVQ    50
    FLAQQSLSLA PVTAATARTA LSGLSGADGR REERGRGKSW VCLSLGGSGN 100
    TEPQKKGLSC RLWDSDILCL PGDIVPAPGP VLAPTHLQTE LVLRCQKETD 150
    CDLCLRVAVH LAVHGHWEEP EDEEKFGGAA DSGVEEPRNA SLQAQVVLSF 200
    QAYPTARCVL LEVQVPAALV QFGQSVGSVV YDCFEAALGS EVRIWSYTQP 250
    RYEKELNHTQ QLPDCRGLEV WNSIPSCWAL PWLNVSADGD NVHLVLNVSE 300
    EQHFGLSLYW NQVQGPPKPR WHKNLTGPQI ITLNHTDLVP CLCIQVWPLE 350
    PDSVRTNICP FREDPRAHQN LWQAARLQLL TLQSWLLDAP CSLPAEAALC 400
    WRAPGGDPCQ PLVPPLSWEN VTVDKVLEFP LLKGHPNLCV QVNSSEKLQL 450
    QECLWADSLG PLKDDVLLLE TRGPQDNRSL CALEPSGCTS LPSKASTRAA 500
    RLGEYLLQDL QSGQCLQLWD DDLGALWACP MDKYIHKRWA LVWLACLLFA 550
    AALSLILLLK KDHAKGWLRL LKQDVRSGAA ARGRAALLLY SADDSGFERL 600
    VGALASALCQ LPLRVAVDLW SRRELSAQGP VAWFHAQRRQ TLQEGGVVVL 650
    LFSPGAVALC SEWLQDGVSG PGAHGPHDAF RASLSCVLPD FLQGRAPGSY 700
    VGACFDRLLH PDAVPALFRT VPVFTLPSQL PDFLGALQQP RAPRSGRLQE 750
    RAEQVSRALQ PALDSYFHPP GTPAPGRGVG PGAGPGAGDG T 791

    Note: No experimental confirmation available.

    Length:791
    Mass (Da):86,240
    Last modified:May 5, 2009 - v2
    Checksum:iE9A4032C17ECD4AF
    GO
    Isoform 2 (identifier: Q8NAC3-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         36-106: Missing.

    Show »
    Length:720
    Mass (Da):78,689
    Checksum:i598203CD77A72647
    GO
    Isoform 3 (identifier: Q8NAC3-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         36-106: Missing.
         264-278: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:705
    Mass (Da):76,942
    Checksum:iE665E2494E795EFF
    GO
    Isoform 4 (identifier: Q8NAC3-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         36-106: Missing.
         264-278: Missing.
         579-624: AAARGRAALL...VAVDLWSRRE → GEWEQALGGG...PRGSAPLLSR
         625-791: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:538
    Mass (Da):59,100
    Checksum:i55E6359DA6A5AF4B
    GO
    Isoform 5 (identifier: Q8NAC3-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         36-106: Missing.
         566-578: Missing.

    Note: Gene prediction based on EST data.

    Show »
    Length:707
    Mass (Da):77,179
    Checksum:i3BED07CC5C11A8B3
    GO
    Isoform 6 (identifier: Q8NAC3-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         36-106: Missing.
         264-278: Missing.
         425-441: Missing.

    Note: Gene prediction based on EST data.

    Show »
    Length:688
    Mass (Da):75,025
    Checksum:iA3A8A825FDD77893
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti241 – 2411E → G in AAQ89199. (PubMed:12975309)Curated
    Sequence conflicti378 – 3781Q → R in AAM77569. 1 PublicationCurated
    Sequence conflicti378 – 3781Q → R in AAQ89199. (PubMed:12975309)Curated
    Sequence conflicti378 – 3781Q → R in AAQ89456. (PubMed:12975309)Curated
    Sequence conflicti378 – 3781Q → R in BAC04001. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti182 – 1821S → L.2 Publications
    Corresponds to variant rs708567 [ dbSNP | Ensembl ].
    VAR_022680

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei36 – 10671Missing in isoform 2, isoform 3, isoform 4, isoform 5 and isoform 6. 3 PublicationsVSP_014138Add
    BLAST
    Alternative sequencei264 – 27815Missing in isoform 3, isoform 4 and isoform 6. 2 PublicationsVSP_014139Add
    BLAST
    Alternative sequencei425 – 44117Missing in isoform 6. CuratedVSP_047291Add
    BLAST
    Alternative sequencei566 – 57813Missing in isoform 5. CuratedVSP_047292Add
    BLAST
    Alternative sequencei579 – 62446AAARG…WSRRE → GEWEQALGGGPPPGSQACAS SPLPSPSVFSGSGRQGPRGS APLLSR in isoform 4. 1 PublicationVSP_014140Add
    BLAST
    Alternative sequencei625 – 791167Missing in isoform 4. 1 PublicationVSP_014141Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF458065 mRNA. Translation: AAM77569.1.
    AY358840 mRNA. Translation: AAQ89199.1.
    AY359098 mRNA. Translation: AAQ89456.1.
    AK092907 mRNA. Translation: BAC04001.1.
    AC018809 Genomic DNA. No translation available.
    BC006411 mRNA. No translation available.
    CCDSiCCDS2590.1. [Q8NAC3-1]
    CCDS2591.2. [Q8NAC3-3]
    CCDS46746.1. [Q8NAC3-2]
    CCDS56240.1. [Q8NAC3-5]
    CCDS56241.1. [Q8NAC3-6]
    RefSeqiNP_001190192.1. NM_001203263.1.
    NP_001190193.1. NM_001203264.1.
    NP_001190194.1. NM_001203265.1.
    NP_116121.2. NM_032732.5.
    NP_703190.1. NM_153460.3.
    NP_703191.1. NM_153461.3.
    UniGeneiHs.129959.

    Genome annotation databases

    EnsembliENST00000295981; ENSP00000295981; ENSG00000163702. [Q8NAC3-1]
    ENST00000383812; ENSP00000373323; ENSG00000163702. [Q8NAC3-3]
    ENST00000403601; ENSP00000384969; ENSG00000163702. [Q8NAC3-2]
    ENST00000413608; ENSP00000396064; ENSG00000163702. [Q8NAC3-5]
    ENST00000455057; ENSP00000407894; ENSG00000163702. [Q8NAC3-6]
    GeneIDi84818.
    KEGGihsa:84818.
    UCSCiuc003btz.3. human. [Q8NAC3-2]
    uc003bua.3. human. [Q8NAC3-1]
    uc003bub.3. human. [Q8NAC3-3]
    uc011atq.2. human. [Q8NAC3-4]

    Polymorphism databases

    DMDMi229462881.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF458065 mRNA. Translation: AAM77569.1 .
    AY358840 mRNA. Translation: AAQ89199.1 .
    AY359098 mRNA. Translation: AAQ89456.1 .
    AK092907 mRNA. Translation: BAC04001.1 .
    AC018809 Genomic DNA. No translation available.
    BC006411 mRNA. No translation available.
    CCDSi CCDS2590.1. [Q8NAC3-1 ]
    CCDS2591.2. [Q8NAC3-3 ]
    CCDS46746.1. [Q8NAC3-2 ]
    CCDS56240.1. [Q8NAC3-5 ]
    CCDS56241.1. [Q8NAC3-6 ]
    RefSeqi NP_001190192.1. NM_001203263.1.
    NP_001190193.1. NM_001203264.1.
    NP_001190194.1. NM_001203265.1.
    NP_116121.2. NM_032732.5.
    NP_703190.1. NM_153460.3.
    NP_703191.1. NM_153461.3.
    UniGenei Hs.129959.

    3D structure databases

    ProteinModelPortali Q8NAC3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 124278. 1 interaction.
    STRINGi 9606.ENSP00000295981.

    PTM databases

    PhosphoSitei Q8NAC3.

    Polymorphism databases

    DMDMi 229462881.

    Proteomic databases

    PaxDbi Q8NAC3.
    PRIDEi Q8NAC3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000295981 ; ENSP00000295981 ; ENSG00000163702 . [Q8NAC3-1 ]
    ENST00000383812 ; ENSP00000373323 ; ENSG00000163702 . [Q8NAC3-3 ]
    ENST00000403601 ; ENSP00000384969 ; ENSG00000163702 . [Q8NAC3-2 ]
    ENST00000413608 ; ENSP00000396064 ; ENSG00000163702 . [Q8NAC3-5 ]
    ENST00000455057 ; ENSP00000407894 ; ENSG00000163702 . [Q8NAC3-6 ]
    GeneIDi 84818.
    KEGGi hsa:84818.
    UCSCi uc003btz.3. human. [Q8NAC3-2 ]
    uc003bua.3. human. [Q8NAC3-1 ]
    uc003bub.3. human. [Q8NAC3-3 ]
    uc011atq.2. human. [Q8NAC3-4 ]

    Organism-specific databases

    CTDi 84818.
    GeneCardsi GC03P009958.
    HGNCi HGNC:18358. IL17RC.
    HPAi CAB026255.
    HPA019885.
    MIMi 610925. gene.
    neXtProti NX_Q8NAC3.
    PharmGKBi PA134986616.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45936.
    HOGENOMi HOG000112986.
    HOVERGENi HBG081776.
    InParanoidi Q8NAC3.
    KOi K05166.
    OMAi GQCLQLW.
    OrthoDBi EOG7J4466.
    PhylomeDBi Q8NAC3.
    TreeFami TF335852.

    Miscellaneous databases

    GeneWikii IL17RC.
    GenomeRNAii 84818.
    NextBioi 35502048.
    PROi Q8NAC3.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8NAC3.
    Bgeei Q8NAC3.
    CleanExi HS_IL17RC.
    Genevestigatori Q8NAC3.

    Family and domain databases

    InterProi IPR027841. IL-17_rcpt_C/E_N.
    IPR013568. SEFIR.
    [Graphical view ]
    Pfami PF15037. IL17_R_N. 1 hit.
    PF08357. SEFIR. 1 hit.
    [Graphical view ]
    PROSITEi PS51534. SEFIR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of novel IL-17 related receptors."
      Gilbert J.M., Gorman D.M.
      Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT LEU-182.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT LEU-182.
      Tissue: Spleen.
    4. "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
      , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
      Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Uterus.
    6. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z., Henzel W.J.
      Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 21-35.
    7. "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer."
      Haudenschild D., Moseley T., Rose L., Reddi A.H.
      J. Biol. Chem. 277:4309-4316(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: ALTERNATIVE SPLICING, TISSUE SPECIFICITY.
    8. "Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells."
      Gerritsen M.E., Tomlinson J.E., Zlot C., Ziman M., Hwang S.
      Br. J. Pharmacol. 140:595-610(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION BY HGF AND VEGF.

    Entry informationi

    Entry nameiI17RC_HUMAN
    AccessioniPrimary (citable) accession number: Q8NAC3
    Secondary accession number(s): E9PHG1
    , E9PHJ6, Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 21, 2005
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 101 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3