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Q8NA70

- FA47B_HUMAN

UniProt

Q8NA70 - FA47B_HUMAN

Protein

Protein FAM47B

Gene

FAM47B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 2 (19 Jul 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM47B
    Gene namesi
    Name:FAM47B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:26659. FAM47B.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134969396.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 645645Protein FAM47BPRO_0000187038Add
    BLAST

    Proteomic databases

    PaxDbiQ8NA70.
    PRIDEiQ8NA70.

    PTM databases

    PhosphoSiteiQ8NA70.

    Expressioni

    Gene expression databases

    BgeeiQ8NA70.
    CleanExiHS_FAM47B.
    GenevestigatoriQ8NA70.

    Organism-specific databases

    HPAiHPA046829.
    HPA050996.

    Interactioni

    Protein-protein interaction databases

    BioGridi127993. 1 interaction.
    IntActiQ8NA70. 1 interaction.
    STRINGi9606.ENSP00000328307.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NA70.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi189 – 324136Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the FAM47 family.Curated

    Phylogenomic databases

    eggNOGiNOG83278.
    HOGENOMiHOG000112475.
    HOVERGENiHBG076577.
    InParanoidiQ8NA70.
    OMAiFWESCPR.
    OrthoDBiEOG7K0ZBC.
    PhylomeDBiQ8NA70.
    TreeFamiTF340932.

    Sequencei

    Sequence statusi: Complete.

    Q8NA70-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGDRRPQDRP RSQGMDSKPW YCDKPPSKYF AKRKHRRLRF PPVDTQNWVF    50
    VTEGMDDFRY ACQSPEDTLV CRRDEFLLPK ISLRGPQADR KSRKKKLLKK 100
    AALFSELSPV QPARKAFVEE VEAQLMTKHP LAMYPNLGKD MPPDLLLQVL 150
    KQLDPERKLE DAWARCEARE KTTEVPTESG KYPCGESCPR PPETPVSRLR 200
    PQLPKTPVSS RRPEPPKTRV SSLRPEPPKT RVSSLHPEPP ETRASHLRVD 250
    PPETGVSHLC PEPPKTLVSS VHPEPPDTGA SHLCPEPPET RVSHLHPEPP 300
    ETGVSHLRPE PSKTQVSSLC PEPPEAGVSH LCLEPPNTHR VSSFLLQVLK 350
    LDSEKKLEDA RARCEGQEMT TEELTKPGKY HFWESCPRPF ESRMPHLRLV 400
    LPITRRMASL CLKPPKTRRV SSLCPEPTKT GASHLKELFQ EDTPSTMECV 450
    SDSLQRRHTS RKLRDFKWAG DLGVNEESIS SLFDFTPECR TTDQDQKIKK 500
    ANECASRLMY GMELDDMDEV EFLRIKYWDR RRRAAPHSYS AQRGRIRYGP 550
    WYFEPKLGKK LRSDEPLIDP KPVLEKPDEP DILDGLYGPI AFKDFILSKG 600
    YRMPGVIEKL FAKKGWTYDS VKTPIQRAVQ VYKYKEDVTD ASKED 645
    Length:645
    Mass (Da):73,945
    Last modified:July 19, 2005 - v2
    Checksum:iF49BACE4627E3C5D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti202 – 2021Q → H in AAH35026. (PubMed:15489334)Curated
    Sequence conflicti220 – 2212VS → AP in BAC04056. (PubMed:14702039)Curated
    Sequence conflicti299 – 2991P → S in BAC04056. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093101 mRNA. Translation: BAC04056.1.
    AL645585 Genomic DNA. Translation: CAI41598.1.
    BC035026 mRNA. Translation: AAH35026.1.
    CCDSiCCDS14236.1.
    RefSeqiNP_689844.2. NM_152631.2.
    UniGeneiHs.197801.

    Genome annotation databases

    EnsembliENST00000329357; ENSP00000328307; ENSG00000189132.
    GeneIDi170062.
    KEGGihsa:170062.
    UCSCiuc004ddi.2. human.

    Polymorphism databases

    DMDMi71151884.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093101 mRNA. Translation: BAC04056.1 .
    AL645585 Genomic DNA. Translation: CAI41598.1 .
    BC035026 mRNA. Translation: AAH35026.1 .
    CCDSi CCDS14236.1.
    RefSeqi NP_689844.2. NM_152631.2.
    UniGenei Hs.197801.

    3D structure databases

    ProteinModelPortali Q8NA70.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 127993. 1 interaction.
    IntActi Q8NA70. 1 interaction.
    STRINGi 9606.ENSP00000328307.

    PTM databases

    PhosphoSitei Q8NA70.

    Polymorphism databases

    DMDMi 71151884.

    Proteomic databases

    PaxDbi Q8NA70.
    PRIDEi Q8NA70.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000329357 ; ENSP00000328307 ; ENSG00000189132 .
    GeneIDi 170062.
    KEGGi hsa:170062.
    UCSCi uc004ddi.2. human.

    Organism-specific databases

    CTDi 170062.
    GeneCardsi GC0XP034870.
    HGNCi HGNC:26659. FAM47B.
    HPAi HPA046829.
    HPA050996.
    neXtProti NX_Q8NA70.
    PharmGKBi PA134969396.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG83278.
    HOGENOMi HOG000112475.
    HOVERGENi HBG076577.
    InParanoidi Q8NA70.
    OMAi FWESCPR.
    OrthoDBi EOG7K0ZBC.
    PhylomeDBi Q8NA70.
    TreeFami TF340932.

    Miscellaneous databases

    GenomeRNAii 170062.
    NextBioi 88858.
    PROi Q8NA70.

    Gene expression databases

    Bgeei Q8NA70.
    CleanExi HS_FAM47B.
    Genevestigatori Q8NA70.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    2. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiFA47B_HUMAN
    AccessioniPrimary (citable) accession number: Q8NA70
    Secondary accession number(s): Q5JQN5, Q6PIG3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2005
    Last sequence update: July 19, 2005
    Last modified: October 1, 2014
    This is version 79 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3