Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Testis-expressed protein 45

Gene

TEX45

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 45
Gene namesi
Name:TEX45Imported
Synonyms:C19orf45
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000198723.10
HGNCiHGNC:24745 TEX45
neXtProtiNX_Q8NA69

Pathology & Biotechi

Organism-specific databases

DisGeNETi374877
OpenTargetsiENSG00000198723
PharmGKBiPA145149520

Polymorphism and mutation databases

BioMutaiC19orf45
DMDMi156630490

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002976601 – 505Testis-expressed protein 45Add BLAST505

Proteomic databases

PaxDbiQ8NA69
PeptideAtlasiQ8NA69
PRIDEiQ8NA69
ProteomicsDBi72648

PTM databases

iPTMnetiQ8NA69
PhosphoSitePlusiQ8NA69

Expressioni

Tissue specificityi

Highly expressed in testis.Curated

Gene expression databases

BgeeiENSG00000198723
CleanExiHS_C19orf45
ExpressionAtlasiQ8NA69 baseline and differential
GenevisibleiQ8NA69 HS

Interactioni

Protein-protein interaction databases

BioGridi131928, 15 interactors
IntActiQ8NA69, 1 interactor
STRINGi9606.ENSP00000355241

Structurei

3D structure databases

ProteinModelPortaliQ8NA69
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IZ35 Eukaryota
ENOG4111PU5 LUCA
GeneTreeiENSGT00390000014215
HOGENOMiHOG000111991
HOVERGENiHBG071731
InParanoidiQ8NA69
OMAiFQESHVP
OrthoDBiEOG091G0V2R
PhylomeDBiQ8NA69
TreeFamiTF336162

Family and domain databases

InterProiView protein in InterPro
IPR028001 DUF4601
PANTHERiPTHR34828 PTHR34828, 1 hit
PfamiView protein in Pfam
PF15373 DUF4601, 1 hit

Sequencei

Sequence statusi: Complete.

Q8NA69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP
60 70 80 90 100
AATREPPSLQ PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ
110 120 130 140 150
ARERTLAMQA GNLHLHEDAH AGIGLSNAHA AYGWPELPAR TRERIRGARL
160 170 180 190 200
IFDRDSLPPG DRDKLRIPPT THQALFPPHD ARPQPRAPSC HLGGPNTLKW
210 220 230 240 250
DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS YGSTCSEQKQ
260 270 280 290 300
AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP
310 320 330 340 350
FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE
360 370 380 390 400
KLQSHVTLGE PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG
410 420 430 440 450
TGEFDFLTMN QKMLKPHRTP PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ
460 470 480 490 500
YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP HQRGCREKID PLVPQPPMYL

CPSQQ
Length:505
Mass (Da):57,331
Last modified:August 21, 2007 - v2
Checksum:i39F780DF2B525E94
GO

Sequence cautioni

The sequence AAH29824 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH34779 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38T → A in BAC04057 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_034664256D → G1 PublicationCorresponds to variant dbSNP:rs484870Ensembl.1
Natural variantiVAR_034665396Y → N1 PublicationCorresponds to variant dbSNP:rs3826736Ensembl.1
Natural variantiVAR_034666434Y → N1 PublicationCorresponds to variant dbSNP:rs475923Ensembl.1
Natural variantiVAR_034667497P → S1 PublicationCorresponds to variant dbSNP:rs1133378Ensembl.1
Natural variantiVAR_034668500L → P1 PublicationCorresponds to variant dbSNP:rs608144Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093103 mRNA Translation: BAC04057.1
AC008878 Genomic DNA No translation available.
BC029824 mRNA Translation: AAH29824.1 Different initiation.
BC034779 mRNA Translation: AAH34779.1 Different initiation.
CCDSiCCDS12179.2
RefSeqiNP_940936.2, NM_198534.2
XP_005272530.1, XM_005272473.3
UniGeneiHs.631862

Genome annotation databases

EnsembliENST00000361664; ENSP00000355241; ENSG00000198723
GeneIDi374877
KEGGihsa:374877
UCSCiuc002mgm.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiTEX45_HUMAN
AccessioniPrimary (citable) accession number: Q8NA69
Secondary accession number(s): Q8N115
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 21, 2007
Last modified: June 20, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health