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Q8NA69

- CS045_HUMAN

UniProt

Q8NA69 - CS045_HUMAN

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Protein

Uncharacterized protein C19orf45

Gene

C19orf45

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C19orf45
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:24745. C19orf45.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145149520.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 505505Uncharacterized protein C19orf45PRO_0000297660Add
BLAST

Proteomic databases

PaxDbiQ8NA69.
PRIDEiQ8NA69.

PTM databases

PhosphoSiteiQ8NA69.

Expressioni

Gene expression databases

BgeeiQ8NA69.
CleanExiHS_C19orf45.
ExpressionAtlasiQ8NA69. baseline and differential.
GenevestigatoriQ8NA69.

Interactioni

Protein-protein interaction databases

BioGridi131928. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ8NA69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG67771.
GeneTreeiENSGT00390000014215.
HOGENOMiHOG000111991.
HOVERGENiHBG071731.
InParanoidiQ8NA69.
OMAiHRDFPAY.
PhylomeDBiQ8NA69.
TreeFamiTF336162.

Family and domain databases

InterProiIPR028001. DUF4601.
[Graphical view]
PfamiPF15373. DUF4601. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8NA69-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP
60 70 80 90 100
AATREPPSLQ PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ
110 120 130 140 150
ARERTLAMQA GNLHLHEDAH AGIGLSNAHA AYGWPELPAR TRERIRGARL
160 170 180 190 200
IFDRDSLPPG DRDKLRIPPT THQALFPPHD ARPQPRAPSC HLGGPNTLKW
210 220 230 240 250
DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS YGSTCSEQKQ
260 270 280 290 300
AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP
310 320 330 340 350
FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE
360 370 380 390 400
KLQSHVTLGE PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG
410 420 430 440 450
TGEFDFLTMN QKMLKPHRTP PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ
460 470 480 490 500
YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP HQRGCREKID PLVPQPPMYL

CPSQQ
Length:505
Mass (Da):57,331
Last modified:August 21, 2007 - v2
Checksum:i39F780DF2B525E94
GO

Sequence cautioni

The sequence AAH29824.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAH34779.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti38 – 381T → A in BAC04057. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti256 – 2561D → G.1 Publication
Corresponds to variant rs484870 [ dbSNP | Ensembl ].
VAR_034664
Natural varianti396 – 3961Y → N.1 Publication
Corresponds to variant rs3826736 [ dbSNP | Ensembl ].
VAR_034665
Natural varianti434 – 4341Y → N.1 Publication
Corresponds to variant rs475923 [ dbSNP | Ensembl ].
VAR_034666
Natural varianti497 – 4971P → S.1 Publication
Corresponds to variant rs1133378 [ dbSNP | Ensembl ].
VAR_034667
Natural varianti500 – 5001L → P.1 Publication
Corresponds to variant rs608144 [ dbSNP | Ensembl ].
VAR_034668

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK093103 mRNA. Translation: BAC04057.1.
BC029824 mRNA. Translation: AAH29824.1. Different initiation.
BC034779 mRNA. Translation: AAH34779.1. Different initiation.
CCDSiCCDS12179.2.
RefSeqiNP_940936.2. NM_198534.2.
XP_005272530.1. XM_005272473.1.
UniGeneiHs.631862.

Genome annotation databases

EnsembliENST00000361664; ENSP00000355241; ENSG00000198723.
GeneIDi374877.
KEGGihsa:374877.
UCSCiuc002mgm.2. human.

Polymorphism databases

DMDMi156630490.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK093103 mRNA. Translation: BAC04057.1 .
BC029824 mRNA. Translation: AAH29824.1 . Different initiation.
BC034779 mRNA. Translation: AAH34779.1 . Different initiation.
CCDSi CCDS12179.2.
RefSeqi NP_940936.2. NM_198534.2.
XP_005272530.1. XM_005272473.1.
UniGenei Hs.631862.

3D structure databases

ProteinModelPortali Q8NA69.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 131928. 1 interaction.

PTM databases

PhosphoSitei Q8NA69.

Polymorphism databases

DMDMi 156630490.

Proteomic databases

PaxDbi Q8NA69.
PRIDEi Q8NA69.

Protocols and materials databases

DNASUi 374877.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000361664 ; ENSP00000355241 ; ENSG00000198723 .
GeneIDi 374877.
KEGGi hsa:374877.
UCSCi uc002mgm.2. human.

Organism-specific databases

CTDi 374877.
GeneCardsi GC19P007469.
HGNCi HGNC:24745. C19orf45.
neXtProti NX_Q8NA69.
PharmGKBi PA145149520.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG67771.
GeneTreei ENSGT00390000014215.
HOGENOMi HOG000111991.
HOVERGENi HBG071731.
InParanoidi Q8NA69.
OMAi HRDFPAY.
PhylomeDBi Q8NA69.
TreeFami TF336162.

Miscellaneous databases

GenomeRNAii 374877.
NextBioi 100299.

Gene expression databases

Bgeei Q8NA69.
CleanExi HS_C19orf45.
ExpressionAtlasi Q8NA69. baseline and differential.
Genevestigatori Q8NA69.

Family and domain databases

InterProi IPR028001. DUF4601.
[Graphical view ]
Pfami PF15373. DUF4601. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-256; ASN-396; ASN-434; SER-497 AND PRO-500.
    Tissue: Testis.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiCS045_HUMAN
AccessioniPrimary (citable) accession number: Q8NA69
Secondary accession number(s): Q8N115
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 21, 2007
Last modified: October 29, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

External Data

Dasty 3