Q8NA69 (CS045_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C19orf45

Gene names

Name:

C19orf45

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence caution

The sequence AAH29824.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH34779.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 505	505	Uncharacterized protein C19orf45		PRO_0000297660
Natural variations
	Natural variant	256	1	D → G. Ref.1 Corresponds to variant rs484870 [ dbSNP | Ensembl ].		VAR_034664
	Natural variant	396	1	Y → N. Ref.1 Corresponds to variant rs3826736 [ dbSNP | Ensembl ].		VAR_034665
	Natural variant	434	1	Y → N. Ref.1 Corresponds to variant rs475923 [ dbSNP | Ensembl ].		VAR_034666
	Natural variant	497	1	P → S. Ref.1 Corresponds to variant rs1133378 [ dbSNP | Ensembl ].		VAR_034667
	Natural variant	500	1	L → P. Ref.1 Corresponds to variant rs608144 [ dbSNP | Ensembl ].		VAR_034668
Experimental info
	Sequence conflict	38	1	T → A in BAC04057. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q8NA69 [UniParc]. Last modified August 21, 2007. Version 2. Checksum: 39F780DF2B525E94	FASTA	505	57,331
	10 20 30 40 50 60 MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP AATREPPSLQ 70 80 90 100 110 120 PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ ARERTLAMQA GNLHLHEDAH 130 140 150 160 170 180 AGIGLSNAHA AYGWPELPAR TRERIRGARL IFDRDSLPPG DRDKLRIPPT THQALFPPHD 190 200 210 220 230 240 ARPQPRAPSC HLGGPNTLKW DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS 250 260 270 280 290 300 YGSTCSEQKQ AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP 310 320 330 340 350 360 FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE KLQSHVTLGE 370 380 390 400 410 420 PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG TGEFDFLTMN QKMLKPHRTP 430 440 450 460 470 480 PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP 490 500 HQRGCREKID PLVPQPPMYL CPSQQ

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-256; ASN-396; ASN-434; SER-497 AND PRO-500. Tissue: Testis.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK093103 mRNA. Translation: BAC04057.1. BC029824 mRNA. Translation: AAH29824.1. Different initiation. BC034779 mRNA. Translation: AAH34779.1. Different initiation.
IPI	IPI00373926.
RefSeq	NP_940936.2. NM_198534.2.
UniGene	Hs.631862.
3D structure databases
ProteinModelPortal	Q8NA69.
ModBase	Search...
PTM databases
PhosphoSite	Q8NA69.
Polymorphism databases
DMDM	156630490.
Proteomic databases
PaxDb	Q8NA69.
PRIDE	Q8NA69.
Protocols and materials databases
DNASU	374877.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000361664; ENSP00000355241; ENSG00000198723.
GeneID	374877.
KEGG	hsa:374877.
UCSC	uc002mgm.2. human.
Organism-specific databases
CTD	374877.
GeneCards	GC19P007469.
HGNC	HGNC:24745. C19orf45.
neXtProt	NX_Q8NA69.
PharmGKB	PA145149520.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG67771.
HOGENOM	HOG000111991.
HOVERGEN	HBG071731.
InParanoid	Q8NA69.
OMA	HRDFPAY.
PhylomeDB	Q8NA69.
Gene expression databases
ArrayExpress	Q8NA69.
Bgee	Q8NA69.
CleanEx	HS_C19orf45.
Genevestigator	Q8NA69.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	374877.
NextBio	100299.

Entry information

Entry name

CS045_HUMAN

Accession

Primary (citable) accession number: Q8NA69
Secondary accession number(s): Q8N115

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	April 3, 2013
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.