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Q8NA69 (CS045_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C19orf45
Gene names
Name:C19orf45
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence caution

The sequence AAH29824.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAH34779.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 505505Uncharacterized protein C19orf45
PRO_0000297660

Natural variations

Natural variant2561D → G. Ref.1
Corresponds to variant rs484870 [ dbSNP | Ensembl ].
VAR_034664
Natural variant3961Y → N. Ref.1
Corresponds to variant rs3826736 [ dbSNP | Ensembl ].
VAR_034665
Natural variant4341Y → N. Ref.1
Corresponds to variant rs475923 [ dbSNP | Ensembl ].
VAR_034666
Natural variant4971P → S. Ref.1
Corresponds to variant rs1133378 [ dbSNP | Ensembl ].
VAR_034667
Natural variant5001L → P. Ref.1
Corresponds to variant rs608144 [ dbSNP | Ensembl ].
VAR_034668

Experimental info

Sequence conflict381T → A in BAC04057. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q8NA69 [UniParc].

Last modified August 21, 2007. Version 2.
Checksum: 39F780DF2B525E94

FASTA50557,331
        10         20         30         40         50         60 
MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP AATREPPSLQ 

        70         80         90        100        110        120 
PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ ARERTLAMQA GNLHLHEDAH 

       130        140        150        160        170        180 
AGIGLSNAHA AYGWPELPAR TRERIRGARL IFDRDSLPPG DRDKLRIPPT THQALFPPHD 

       190        200        210        220        230        240 
ARPQPRAPSC HLGGPNTLKW DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS 

       250        260        270        280        290        300 
YGSTCSEQKQ AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP 

       310        320        330        340        350        360 
FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE KLQSHVTLGE 

       370        380        390        400        410        420 
PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG TGEFDFLTMN QKMLKPHRTP 

       430        440        450        460        470        480 
PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP 

       490        500 
HQRGCREKID PLVPQPPMYL CPSQQ 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-256; ASN-396; ASN-434; SER-497 AND PRO-500.
Tissue: Testis.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK093103 mRNA. Translation: BAC04057.1.
BC029824 mRNA. Translation: AAH29824.1. Different initiation.
BC034779 mRNA. Translation: AAH34779.1. Different initiation.
RefSeqNP_940936.2. NM_198534.2.
XP_005272530.1. XM_005272473.1.
UniGeneHs.631862.

3D structure databases

ProteinModelPortalQ8NA69.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid131928. 1 interaction.

PTM databases

PhosphoSiteQ8NA69.

Polymorphism databases

DMDM156630490.

Proteomic databases

PaxDbQ8NA69.
PRIDEQ8NA69.

Protocols and materials databases

DNASU374877.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000361664; ENSP00000355241; ENSG00000198723.
GeneID374877.
KEGGhsa:374877.
UCSCuc002mgm.2. human.

Organism-specific databases

CTD374877.
GeneCardsGC19P007469.
HGNCHGNC:24745. C19orf45.
neXtProtNX_Q8NA69.
PharmGKBPA145149520.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG67771.
HOGENOMHOG000111991.
HOVERGENHBG071731.
InParanoidQ8NA69.
OMAHRDFPAY.
PhylomeDBQ8NA69.
TreeFamTF336162.

Gene expression databases

ArrayExpressQ8NA69.
BgeeQ8NA69.
CleanExHS_C19orf45.
GenevestigatorQ8NA69.

Family and domain databases

InterProIPR028001. DUF4601.
[Graphical view]
PfamPF15373. DUF4601. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi374877.
NextBio100299.

Entry information

Entry nameCS045_HUMAN
AccessionPrimary (citable) accession number: Q8NA69
Secondary accession number(s): Q8N115
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 21, 2007
Last modified: February 19, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM