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Q8NA69

- CS045_HUMAN

UniProt

Q8NA69 - CS045_HUMAN

Protein

Uncharacterized protein C19orf45

Gene

C19orf45

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 2 (21 Aug 2007)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C19orf45
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:24745. C19orf45.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA145149520.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 505505Uncharacterized protein C19orf45PRO_0000297660Add
    BLAST

    Proteomic databases

    PaxDbiQ8NA69.
    PRIDEiQ8NA69.

    PTM databases

    PhosphoSiteiQ8NA69.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8NA69.
    BgeeiQ8NA69.
    CleanExiHS_C19orf45.
    GenevestigatoriQ8NA69.

    Interactioni

    Protein-protein interaction databases

    BioGridi131928. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8NA69.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG67771.
    HOGENOMiHOG000111991.
    HOVERGENiHBG071731.
    InParanoidiQ8NA69.
    OMAiHRDFPAY.
    PhylomeDBiQ8NA69.
    TreeFamiTF336162.

    Family and domain databases

    InterProiIPR028001. DUF4601.
    [Graphical view]
    PfamiPF15373. DUF4601. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8NA69-1 [UniParc]FASTAAdd to Basket

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    MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP    50
    AATREPPSLQ PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ 100
    ARERTLAMQA GNLHLHEDAH AGIGLSNAHA AYGWPELPAR TRERIRGARL 150
    IFDRDSLPPG DRDKLRIPPT THQALFPPHD ARPQPRAPSC HLGGPNTLKW 200
    DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS YGSTCSEQKQ 250
    AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP 300
    FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE 350
    KLQSHVTLGE PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG 400
    TGEFDFLTMN QKMLKPHRTP PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ 450
    YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP HQRGCREKID PLVPQPPMYL 500
    CPSQQ 505
    Length:505
    Mass (Da):57,331
    Last modified:August 21, 2007 - v2
    Checksum:i39F780DF2B525E94
    GO

    Sequence cautioni

    The sequence AAH29824.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAH34779.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti38 – 381T → A in BAC04057. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti256 – 2561D → G.1 Publication
    Corresponds to variant rs484870 [ dbSNP | Ensembl ].
    VAR_034664
    Natural varianti396 – 3961Y → N.1 Publication
    Corresponds to variant rs3826736 [ dbSNP | Ensembl ].
    VAR_034665
    Natural varianti434 – 4341Y → N.1 Publication
    Corresponds to variant rs475923 [ dbSNP | Ensembl ].
    VAR_034666
    Natural varianti497 – 4971P → S.1 Publication
    Corresponds to variant rs1133378 [ dbSNP | Ensembl ].
    VAR_034667
    Natural varianti500 – 5001L → P.1 Publication
    Corresponds to variant rs608144 [ dbSNP | Ensembl ].
    VAR_034668

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093103 mRNA. Translation: BAC04057.1.
    BC029824 mRNA. Translation: AAH29824.1. Different initiation.
    BC034779 mRNA. Translation: AAH34779.1. Different initiation.
    CCDSiCCDS12179.2.
    RefSeqiNP_940936.2. NM_198534.2.
    XP_005272530.1. XM_005272473.1.
    UniGeneiHs.631862.

    Genome annotation databases

    EnsembliENST00000361664; ENSP00000355241; ENSG00000198723.
    GeneIDi374877.
    KEGGihsa:374877.
    UCSCiuc002mgm.2. human.

    Polymorphism databases

    DMDMi156630490.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093103 mRNA. Translation: BAC04057.1 .
    BC029824 mRNA. Translation: AAH29824.1 . Different initiation.
    BC034779 mRNA. Translation: AAH34779.1 . Different initiation.
    CCDSi CCDS12179.2.
    RefSeqi NP_940936.2. NM_198534.2.
    XP_005272530.1. XM_005272473.1.
    UniGenei Hs.631862.

    3D structure databases

    ProteinModelPortali Q8NA69.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 131928. 1 interaction.

    PTM databases

    PhosphoSitei Q8NA69.

    Polymorphism databases

    DMDMi 156630490.

    Proteomic databases

    PaxDbi Q8NA69.
    PRIDEi Q8NA69.

    Protocols and materials databases

    DNASUi 374877.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000361664 ; ENSP00000355241 ; ENSG00000198723 .
    GeneIDi 374877.
    KEGGi hsa:374877.
    UCSCi uc002mgm.2. human.

    Organism-specific databases

    CTDi 374877.
    GeneCardsi GC19P007469.
    HGNCi HGNC:24745. C19orf45.
    neXtProti NX_Q8NA69.
    PharmGKBi PA145149520.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG67771.
    HOGENOMi HOG000111991.
    HOVERGENi HBG071731.
    InParanoidi Q8NA69.
    OMAi HRDFPAY.
    PhylomeDBi Q8NA69.
    TreeFami TF336162.

    Miscellaneous databases

    GenomeRNAii 374877.
    NextBioi 100299.

    Gene expression databases

    ArrayExpressi Q8NA69.
    Bgeei Q8NA69.
    CleanExi HS_C19orf45.
    Genevestigatori Q8NA69.

    Family and domain databases

    InterProi IPR028001. DUF4601.
    [Graphical view ]
    Pfami PF15373. DUF4601. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-256; ASN-396; ASN-434; SER-497 AND PRO-500.
      Tissue: Testis.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiCS045_HUMAN
    AccessioniPrimary (citable) accession number: Q8NA69
    Secondary accession number(s): Q8N115
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 21, 2007
    Last sequence update: August 21, 2007
    Last modified: October 1, 2014
    This is version 73 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3