Q8NA29 (MFS2A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Major facilitator superfamily domain-containing protein 2A

Gene names

Name:	MFSD2A
Synonyms:	MFSD2
ORF Names:	HMFN0656, PP9177, UNQ300/PRO341

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane tunicamycin transporter. Ref.10
Subcellular location	Cell membrane; Multi-pass membrane protein Potential. Endoplasmic reticulum membrane By similarity; Multi-pass membrane protein Potential. Note: Cytoplasmic punctae that may represent vesicles shuttling between the endoplasmic reticulum and the plasma membrane. Ref.10
Post-translational modification	N-glycosylated. Ref.10
Sequence similarities	Belongs to the major facilitator superfamily.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Endoplasmic reticulum Membrane
Coding sequence diversity	Alternative splicing
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8NA29-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8NA29-2)

The sequence of this isoform differs from the canonical sequence as follows:
     77-89: Missing.

Isoform 3 (identifier: Q8NA29-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-186: MAKGEGAESG...PYSALTMFIS → MWLRWALSLP...PTRLSPCSSA

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 543	543	Major facilitator superfamily domain-containing protein 2A		PRO_0000273387
Regions
	Transmembrane	47 – 67	21	Helical; Potential
	Transmembrane	81 – 101	21	Helical; Potential
	Transmembrane	129 – 149	21	Helical; Potential
	Transmembrane	161 – 181	21	Helical; Potential
	Transmembrane	257 – 277	21	Helical; Potential
	Transmembrane	311 – 331	21	Helical; Potential
	Transmembrane	345 – 365	21	Helical; Potential
	Transmembrane	371 – 391	21	Helical; Potential
	Transmembrane	394 – 414	21	Helical; Potential
	Transmembrane	438 – 458	21	Helical; Potential
	Transmembrane	481 – 501	21	Helical; Potential
	Compositional bias	35 – 38	4	Poly-Lys
Amino acid modifications
	Glycosylation	230	1	N-linked (GlcNAc...) Potential
	Glycosylation	240	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 186	186	MAKGE…TMFIS → MWLRWALSLPPSSCLWAEPG MPSQTPWWASASANPPGPAW VALCPGSSSPRPWPSLPTSS SGSCPTSHTARPIGTCFSIA SLKQWSRVSMFPTRLSPCSS A in isoform 3.		VSP_022540
	Alternative sequence	77 – 89	13	Missing in isoform 2.		VSP_022539
Experimental info
	Mutagenesis	103	1	R → A: No effect on cell sensitivity toward tunicamycin. Ref.10
	Mutagenesis	106	1	D → A: No effect on cell sensitivity toward tunicamycin. Ref.10
	Mutagenesis	110	1	D → A: Drastic loss of cell sensitivity toward tunicamycin. Ref.10
	Mutagenesis	230	1	N → Q: Loss of glycosylation; when associated with Q-240. Ref.10
	Mutagenesis	240	1	N → Q: Loss of glycosylation; when associated with Q-230. Ref.10
	Mutagenesis	449	1	K → A: Loss of plasma membrane localization. Loss of cell sensitivity toward tunicamycin. Ref.10
	Sequence conflict	229	1	L → F in AAQ88999. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: C9933B79335BFBDE	FASTA	543	60,170
	10 20 30 40 50 60 MAKGEGAESG SAAGLLPTSI LQSTERPAQV KKEPKKKKQQ LSVCNKLCYA LGGAPYQVTG 70 80 90 100 110 120 CALGFFLQIY LLDVAQKDEE VVFCFSSFQV GPFSASIILF VGRAWDAITD PLVGLCISKS 130 140 150 160 170 180 PWTCLGRLMP WIIFSTPLAV IAYFLIWFVP DFPHGQTYWY LLFYCLFETM VTCFHVPYSA 190 200 210 220 230 240 LTMFISTEQT ERDSATAYRM TVEVLGTVLG TAIQGQIVGQ ADTPCFQDLN SSTVASQSAN 250 260 270 280 290 300 HTHGTTSHRE TQKAYLLAAG VIVCIYIICA VILILGVREQ REPYEAQQSE PIAYFRGLRL 310 320 330 340 350 360 VMSHGPYIKL ITGFLFTSLA FMLVEGNFVL FCTYTLGFRN EFQNLLLAIM LSATLTIPIW 370 380 390 400 410 420 QWFLTRFGKK TAVYVGISSA VPFLILVALM ESNLIITYAV AVAAGISVAA AFLLPWSMLP 430 440 450 460 470 480 DVIDDFHLKQ PHFHGTEPIF FSFYVFFTKF ASGVSLGIST LSLDFAGYQT RGCSQPERVK 490 500 510 520 530 540 FTLNMLVTMA PIVLILLGLL LFKMYPIDEE RRRQNKKALQ ALRDEASSSG CSETDSTELA SIL
	Isoform 2 [UniParc]. Checksum: 3B6978F4EA92C763	FASTA	530	58,624
	10 20 30 40 50 60 MAKGEGAESG SAAGLLPTSI LQSTERPAQV KKEPKKKKQQ LSVCNKLCYA LGGAPYQVTG 70 80 90 100 110 120 CALGFFLQIY LLDVAQVGPF SASIILFVGR AWDAITDPLV GLCISKSPWT CLGRLMPWII 130 140 150 160 170 180 FSTPLAVIAY FLIWFVPDFP HGQTYWYLLF YCLFETMVTC FHVPYSALTM FISTEQTERD 190 200 210 220 230 240 SATAYRMTVE VLGTVLGTAI QGQIVGQADT PCFQDLNSST VASQSANHTH GTTSHRETQK 250 260 270 280 290 300 AYLLAAGVIV CIYIICAVIL ILGVREQREP YEAQQSEPIA YFRGLRLVMS HGPYIKLITG 310 320 330 340 350 360 FLFTSLAFML VEGNFVLFCT YTLGFRNEFQ NLLLAIMLSA TLTIPIWQWF LTRFGKKTAV 370 380 390 400 410 420 YVGISSAVPF LILVALMESN LIITYAVAVA AGISVAAAFL LPWSMLPDVI DDFHLKQPHF 430 440 450 460 470 480 HGTEPIFFSF YVFFTKFASG VSLGISTLSL DFAGYQTRGC SQPERVKFTL NMLVTMAPIV 490 500 510 520 530 LILLGLLLFK MYPIDEERRR QNKKALQALR DEASSSGCSE TDSTELASIL
	Isoform 3 [UniParc]. Checksum: 4C470B6380870E38	FASTA	458	50,230
	10 20 30 40 50 60 MWLRWALSLP PSSCLWAEPG MPSQTPWWAS ASANPPGPAW VALCPGSSSP RPWPSLPTSS 70 80 90 100 110 120 SGSCPTSHTA RPIGTCFSIA SLKQWSRVSM FPTRLSPCSS ATEQTERDSA TAYRMTVEVL 130 140 150 160 170 180 GTVLGTAIQG QIVGQADTPC FQDLNSSTVA SQSANHTHGT TSHRETQKAY LLAAGVIVCI 190 200 210 220 230 240 YIICAVILIL GVREQREPYE AQQSEPIAYF RGLRLVMSHG PYIKLITGFL FTSLAFMLVE 250 260 270 280 290 300 GNFVLFCTYT LGFRNEFQNL LLAIMLSATL TIPIWQWFLT RFGKKTAVYV GISSAVPFLI 310 320 330 340 350 360 LVALMESNLI ITYAVAVAAG ISVAAAFLLP WSMLPDVIDD FHLKQPHFHG TEPIFFSFYV 370 380 390 400 410 420 FFTKFASGVS LGISTLSLDF AGYQTRGCSQ PERVKFTLNM LVTMAPIVLI LLGLLLFKMY 430 440 450 PIDEERRRQN KKALQALRDE ASSSGCSETD STELASIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M. Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2). Tissue: Placenta and Testis.
[3]	"Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas." Yamada S., Ohira M., Horie H., Ando K., Takayasu H., Suzuki Y., Sugano S., Hirata T., Goto T., Matsunaga T., Hiyama E., Hayashi Y., Ando H., Suita S., Kaneko M., Sasaki F., Hashizume K., Ohnuma N., Nakagawara A. Oncogene 23:5901-5911(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Hepatoblastoma.
[4]	"Large-scale cDNA transfection screening for genes related to cancer development and progression." Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X. , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J. Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
[5]	"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y. , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T. DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
[6]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Eye, Muscle and Testis.
[9]	"Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis." Angers M., Uldry M., Kong D., Gimble J.M., Jetten A.M. Biochem. J. 416:347-355(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
[10]	"A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin." Reiling J.H., Clish C.B., Carette J.E., Varadarajan M., Brummelkamp T.R., Sabatini D.M. Proc. Natl. Acad. Sci. U.S.A. 108:11756-11765(2011) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, GLYCOSYLATION, MUTAGENESIS OF ARG-103; ASP-106; ASP-110; ASN-230; ASN-240 AND LYS-449.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY358636 mRNA. Translation: AAQ88999.1. AK093223 mRNA. Translation: BAC04100.1. AB073383 mRNA. Translation: BAD38634.1. AF289609 mRNA. Translation: AAL55793.1. AK075183 mRNA. Translation: BAC11456.1. AK291540 mRNA. Translation: BAF84229.1. AL663070 Genomic DNA. Translation: CAI20268.1. AL663070 Genomic DNA. Translation: CAI20269.1. CH471059 Genomic DNA. Translation: EAX07248.1. BC006353 mRNA. Translation: AAH06353.2. BC011587 mRNA. Translation: AAH11587.1. BC092414 mRNA. Translation: AAH92414.1.
IPI	IPI00410391. IPI00647701. IPI00827704.
RefSeq	NP_001129965.1. NM_001136493.1. NP_116182.2. NM_032793.3.
UniGene	Hs.655177.
3D structure databases
ProteinModelPortal	Q8NA29.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-47306N.
STRING	9606.ENSP00000361895.
Protein family/group databases
TCDB	2.A.2.3.8. glycoside-pentoside-hexuronide (GPH):cation symporter family.
PTM databases
PhosphoSite	Q8NA29.
Polymorphism databases
DMDM	74751132.
Proteomic databases
PaxDb	Q8NA29.
PRIDE	Q8NA29.
Protocols and materials databases
DNASU	84879.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000372809; ENSP00000361895; ENSG00000168389. ENST00000372811; ENSP00000361898; ENSG00000168389.
GeneID	84879.
KEGG	hsa:84879.
UCSC	uc001ceu.3. human. uc001cev.3. human.
Organism-specific databases
CTD	84879.
GeneCards	GC01P040421.
HGNC	HGNC:25897. MFSD2A.
HPA	HPA043107.
MIM	614397. gene.
neXtProt	NX_Q8NA29.
PharmGKB	PA165751549.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG2211.
HOGENOM	HOG000294186.
HOVERGEN	HBG080097.
InParanoid	Q8NA29.
OMA	VAQVDPF.
OrthoDB	EOG49S66D.
PhylomeDB	Q8NA29.
Gene expression databases
ArrayExpress	Q8NA29.
Bgee	Q8NA29.
CleanEx	HS_MFSD2.
Genevestigator	Q8NA29.
Family and domain databases
InterPro	IPR016196. MFS_dom_general_subst_transpt. [Graphical view]
SUPFAM	SSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITE	PS50850. MFS. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	mfsd2a. human.
GenomeRNAi	84879.
NextBio	75189.
SOURCE	Search...

Entry information

Entry name

MFS2A_HUMAN

Accession

Primary (citable) accession number: Q8NA29
Secondary accession number(s): A8K675 , Q6UWU5, Q96F59, Q9BRC8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.