Unreviewed, UniProtKB/TrEMBL Q8N9J3 (Q8N9J3_HUMAN)

Names and origin

Protein names	Submitted name:     cDNA FLJ37047 fis, clone BRACE2012232, highly similar to Homo sapiens cadherin 20 (CDH20) mRNA EMBL BAC04340.1
Organism	Homo sapiens (Human) EMBL BAC04340.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Cadherins are calcium dependent cell adhesion proteins By similarity. RuleBase RU004357V0
Subcellular location	Membrane; Single-pass type I membrane protein By similarity. RuleBase RU003318V0

Ontologies

Keywords
Biological process	Cell adhesion RuleBase RU003318V0 Spearmint SPM002126
Cellular component	Cell membrane Spearmint SPM002126 Membrane
Domain	Repeat Spearmint SPM002126 Transmembrane RuleBase RU003318V0 Spearmint SPM002126
Ligand	Calcium RuleBase RU000484V3 Spearmint SPM002126
Gene Ontology (GO)
Biological process	homophilic cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8N9J3-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: AD9BD604DE4CE1A0	FASTA	335	37,141
	10 20 30 40 50 60 MEMNNPSQVG SVPVTIKVLD VNDNAPEFPR FYEAFVCENA KAGQLIQTVS AVDQDDPRNG 70 80 90 100 110 120 QHFYYSLAPE AANNPNFTIR DNQDNTARIL TRRSGFRQQE QSVFHLPILI ADSGQPVLSS 130 140 150 160 170 180 TGTLTIQVCS CDDDGHVMSC SPEAYMLPVS LSRGALIAIL ACIFVLLVLV LLILSMRRHR 190 200 210 220 230 240 KQPYIIDDEE NIHENIVRYD DEGGGEEDTE AFDIAAMWNP REAQAGAAPK TRQDMLPEIE 250 260 270 280 290 300 SLSRYVPQTC AVNSTVHSYV LAKLYEADMD LWAPPFDSLQ TYMFEGDGSV AGSLSSLQSA 310 320 330 TSDSEQSFDF LTDWGPRFRK LAELYGASEG PAPLW

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAC04340.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK094366 mRNA. Translation: BAC04340.1.
IPI	IPI00307612.
UniGene	Hs.671510
3D structure databases
HSSP	HSSP built from PDB template 1I7X based on UniProtKB P09803.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000101542. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:1760. CDH20.
Phylogenomic databases
HOVERGEN	Q8N9J3.
Gene expression databases
ArrayExpress	Q8N9J3.
Bgee	Q8N9J3.
Family and domain databases
InterPro	IPR002126. Cadherin. IPR000233. Cadherin_C_term. [Graphical view]
Gene3D	G3DSA:2.60.40.60. Cadherin. 1 hit.
Pfam	PF00028. Cadherin. 1 hit. PF01049. Cadherin_C. 1 hit. [Graphical view]
SMART	SM00112. CA. 1 hit. [Graphical view]
PROSITE	PS00232. CADHERIN_1. 1 hit. PS50268. CADHERIN_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8N9J3_HUMAN

Accession

Primary (citable) accession number: Q8N9J3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)