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Protein

Protein FAM133A

Gene

FAM133A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM133A
Gene namesi
Name:FAM133A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000179083.6
HGNCiHGNC:26748 FAM133A
neXtProtiNX_Q8N9E0

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179083
PharmGKBiPA162386125

Polymorphism and mutation databases

BioMutaiFAM133A
DMDMi74751120

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002876191 – 248Protein FAM133AAdd BLAST248

Proteomic databases

EPDiQ8N9E0
MaxQBiQ8N9E0
PaxDbiQ8N9E0
PeptideAtlasiQ8N9E0
PRIDEiQ8N9E0
ProteomicsDBi72524

PTM databases

iPTMnetiQ8N9E0
PhosphoSitePlusiQ8N9E0

Expressioni

Gene expression databases

BgeeiENSG00000179083
CleanExiHS_FAM133A
GenevisibleiQ8N9E0 HS

Organism-specific databases

HPAiHPA066175
HPA069513

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi130395, 8 interactors
IntActiQ8N9E0, 13 interactors
STRINGi9606.ENSP00000318974

Structurei

3D structure databases

ProteinModelPortaliQ8N9E0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi45 – 240Lys-richAdd BLAST196
Compositional biasi82 – 198Ser-richAdd BLAST117

Sequence similaritiesi

Belongs to the FAM133 family.Curated

Phylogenomic databases

eggNOGiENOG410IY68 Eukaryota
ENOG41123P0 LUCA
GeneTreeiENSGT00730000111097
HOGENOMiHOG000059590
HOVERGENiHBG088046
InParanoidiQ8N9E0
OMAiKQHKKHS
OrthoDBiEOG091G0ZD9
PhylomeDBiQ8N9E0
TreeFamiTF350193

Family and domain databases

InterProiView protein in InterPro
IPR026766 Fam133
PANTHERiPTHR31911 PTHR31911, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N9E0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKRDNRVAY MNPIAMARWR GPTQSVGPTI QDYLNRPRPT WEEVKKQLEN
60 70 80 90 100
KKTGSKALAE FEEKMNENWK KELEKSREKL LSGNESSSKK RERKKKRKKK
110 120 130 140 150
SCRSSSSSSS SDSSSSSSDS EDEEKKQGKR RKKKKNRSYK SSQSSTHESE
160 170 180 190 200
SESKESVKKK KKSKDETEKE KDVRSLSKKR KKSYPDDKPL SSESSSESDY
210 220 230 240
EEDVQAKKKR RCEEREQAKE KVKKKKKKQH KKHSKKKKKK SGSSHKSR
Length:248
Mass (Da):28,941
Last modified:October 1, 2002 - v1
Checksum:iDB18B8F3FABFBAF6
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05390767E → K. Corresponds to variant dbSNP:rs34123774Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK094978 mRNA Translation: BAC04467.1
AL009173 Genomic DNA No translation available.
BC113387 mRNA Translation: AAI13388.1
BC113385 mRNA Translation: AAI13386.1
CCDSiCCDS14466.1
RefSeqiNP_001164580.1, NM_001171109.1
NP_001164581.1, NM_001171110.1
NP_001164582.1, NM_001171111.1
NP_775969.1, NM_173698.2
XP_006724704.1, XM_006724641.3
XP_011529227.1, XM_011530925.2
XP_011529228.1, XM_011530926.2
XP_011529229.1, XM_011530927.2
XP_011529230.1, XM_011530928.1
XP_011529231.1, XM_011530929.1
XP_011529233.1, XM_011530931.2
XP_016884943.1, XM_017029454.1
XP_016884944.1, XM_017029455.1
XP_016884945.1, XM_017029456.1
UniGeneiHs.110069

Genome annotation databases

EnsembliENST00000322139; ENSP00000318974; ENSG00000179083
ENST00000332647; ENSP00000362169; ENSG00000179083
GeneIDi286499
KEGGihsa:286499
UCSCiuc004efr.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiF133A_HUMAN
AccessioniPrimary (citable) accession number: Q8N9E0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

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