Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein C12orf29

Gene

C12orf29

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C12orf29
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000133641.17
HGNCiHGNC:25322 C12orf29
neXtProtiNX_Q8N999

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000133641
PharmGKBiPA143485359

Polymorphism and mutation databases

BioMutaiC12orf29
DMDMi158706467

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003052721 – 325Uncharacterized protein C12orf29Add BLAST325

Proteomic databases

EPDiQ8N999
MaxQBiQ8N999
PaxDbiQ8N999
PeptideAtlasiQ8N999
PRIDEiQ8N999
ProteomicsDBi72510
72511 [Q8N999-2]
72512 [Q8N999-3]

PTM databases

iPTMnetiQ8N999
PhosphoSitePlusiQ8N999

Expressioni

Gene expression databases

BgeeiENSG00000133641
CleanExiHS_C12orf29
ExpressionAtlasiQ8N999 baseline and differential
GenevisibleiQ8N999 HS

Organism-specific databases

HPAiHPA039663

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349358

Structurei

3D structure databases

ProteinModelPortaliQ8N999
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IEPK Eukaryota
ENOG4110N6G LUCA
GeneTreeiENSGT00500000044938
HOGENOMiHOG000057278
HOVERGENiHBG107705
InParanoidiQ8N999
OMAiREHQPFK
OrthoDBiEOG091G09NV
PhylomeDBiQ8N999
TreeFamiTF328501

Family and domain databases

InterProiView protein in InterPro
IPR038761 C12orf29
PANTHERiPTHR31219 PTHR31219, 1 hit

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8N999-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKRLGSVQRK MPCVFVTEVK EEPSSKREHQ PFKVLATETV SHKALDADIY
60 70 80 90 100
SAIPTEKVDG TCCYVTTYKD QPYLWARLDR KPNKQAEKRF KNFLHSKENP
110 120 130 140 150
KEFFWNVEED FKPAPECWIP AKETEQINGN PVPDENGHIP GWVPVEKNNK
160 170 180 190 200
QYCWHSSVVN YEFEIALVLK HHPDDSGLLE ISAVPLSDLL EQTLELIGTN
210 220 230 240 250
INGNPYGLGS KKHPLHLLIP HGAFQIRNLP SLKHNDLVSW FEDCKEGKIE
260 270 280 290 300
GIVWHCSDGC LIKVHRHHLG LCWPIPDTYM NSRPVIINMN LNKCDSAFDI
310 320
KCLFNHFLKI DNQKFVRLKD IIFDV
Length:325
Mass (Da):37,490
Last modified:October 2, 2007 - v2
Checksum:i348F2FB665137DAC
GO
Isoform 2 (identifier: Q8N999-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     31-38: PFKVLATE → ISHTFGLD
     39-325: Missing.

Show »
Length:38
Mass (Da):4,416
Checksum:iD2BB9CDD4F699045
GO
Isoform 3 (identifier: Q8N999-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-29: MKRLGSVQRKMPCVFVTEVKEEPSSKREH → MSLPF
     140-140: P → PG

Show »
Length:302
Mass (Da):34,724
Checksum:i123638567219DCC9
GO

Sequence cautioni

The sequence AAH35136 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence AAH58014 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti87E → K in AAH92422 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03519723P → L1 PublicationCorresponds to variant dbSNP:rs11541954Ensembl.1
Natural variantiVAR_035198238V → L2 PublicationsCorresponds to variant dbSNP:rs9262Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0283161 – 29MKRLG…SKREH → MSLPF in isoform 3. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_02831731 – 38PFKVLATE → ISHTFGLD in isoform 2. 2 Publications8
Alternative sequenceiVSP_02831839 – 325Missing in isoform 2. 2 PublicationsAdd BLAST287
Alternative sequenceiVSP_028319140P → PG in isoform 3. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095477 mRNA Translation: BAC04555.1
AL137488 mRNA Translation: CAB70767.2
BX537868 mRNA Translation: CAD97870.1
BX640968 mRNA Translation: CAE45983.1
BX648026 mRNA Translation: CAH10541.1
CH471054 Genomic DNA Translation: EAW97411.1
BC035136 mRNA Translation: AAH35136.2 Sequence problems.
BC058014 mRNA Translation: AAH58014.1 Sequence problems.
BC092422 mRNA Translation: AAH92422.1
CCDSiCCDS31866.1 [Q8N999-1]
PIRiT46472
RefSeqiNP_001009894.2, NM_001009894.2 [Q8N999-1]
UniGeneiHs.591009

Genome annotation databases

EnsembliENST00000356891; ENSP00000349358; ENSG00000133641 [Q8N999-1]
ENST00000453037; ENSP00000402018; ENSG00000133641 [Q8N999-2]
ENST00000550333; ENSP00000448194; ENSG00000133641 [Q8N999-2]
ENST00000552121; ENSP00000447327; ENSG00000133641 [Q8N999-2]
GeneIDi91298
KEGGihsa:91298
UCSCiuc001tao.4 human [Q8N999-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCL029_HUMAN
AccessioniPrimary (citable) accession number: Q8N999
Secondary accession number(s): Q569K5
, Q6AWA8, Q6PEK5, Q8IYQ5, Q9NT75
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: October 2, 2007
Last modified: June 20, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health