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Protein

Coiled-coil domain-containing protein 89

Gene

CCDC89

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 89
Alternative name(s):
Bc8 orange-interacting protein
Gene namesi
Name:CCDC89
Synonyms:BOIP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000179071.4
HGNCiHGNC:26762 CCDC89
neXtProtiNX_Q8N998

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179071
PharmGKBiPA144596457

Polymorphism and mutation databases

BioMutaiCCDC89
DMDMi74729632

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002710241 – 374Coiled-coil domain-containing protein 89Add BLAST374

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei16PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8N998
PeptideAtlasiQ8N998
PRIDEiQ8N998
ProteomicsDBi72509

PTM databases

iPTMnetiQ8N998
PhosphoSitePlusiQ8N998

Expressioni

Gene expression databases

BgeeiENSG00000179071
CleanExiHS_CCDC89

Organism-specific databases

HPAiHPA040628

Interactioni

Subunit structurei

Interacts with HEY1.By similarity

Protein-protein interaction databases

BioGridi128643, 11 interactors
IntActiQ8N998, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8N998
SMRiQ8N998
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili20 – 351Sequence analysisAdd BLAST332

Sequence similaritiesi

Belongs to the CCDC89 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IHI9 Eukaryota
ENOG4111GX6 LUCA
GeneTreeiENSGT00390000016046
HOGENOMiHOG000007171
HOVERGENiHBG081050
InParanoidiQ8N998
OMAiQSQLICI
OrthoDBiEOG091G0KSH
PhylomeDBiQ8N998
TreeFamiTF333232

Sequencei

Sequence statusi: Complete.

Q8N998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAPMLQKQQ APRMDTPPPE ERLEKQNEKL NNQEEETEFK ELDGLREALA
60 70 80 90 100
NLRGLSEEER SEKAMLRSRI EEQSQLICIL KRRSDEALER CQILELLNAE
110 120 130 140 150
LEEKMMQEAE KLKAQGEYSR KLEERFMTLA ANHELMLRFK DEYKSENIKL
160 170 180 190 200
REENEKLRLE NSSLFSQALK DEEAKVLQLT VRCEALTGEL ETLKERCAQD
210 220 230 240 250
ACQAQAREKE LLELQSQQAC THTKETEQLR SQLQTLKQQH QQAVEQIAKA
260 270 280 290 300
EETHSSLSQE LQARLQTVTR EKEELLQLSI ERGKVLQNKQ AEICQLEEKL
310 320 330 340 350
EIANEDRKHA LERFEQEAVA VDSNLRVREL QRKVDGIQKA YDELRLQSEA
360 370
FKKHSLDLLS KERELNGKLR HLSP
Length:374
Mass (Da):43,809
Last modified:October 1, 2002 - v1
Checksum:i161160AC06AC1491
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095478 mRNA Translation: BAC04556.1
BC044814 mRNA Translation: AAH44814.1
CCDSiCCDS8270.1
RefSeqiNP_689936.1, NM_152723.2
UniGeneiHs.376241

Genome annotation databases

EnsembliENST00000316398; ENSP00000320649; ENSG00000179071
GeneIDi220388
KEGGihsa:220388
UCSCiuc001pau.2 human

Similar proteinsi

Entry informationi

Entry nameiCCD89_HUMAN
AccessioniPrimary (citable) accession number: Q8N998
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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