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Q8N8Y5 (ZFP41_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein 41 homolog

Short name=Zfp-41
Gene names
Name:ZFP41
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Contains 4 C2H2-type zinc fingers.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Zinc finger protein 41 homolog
PRO_0000296186

Regions

Zinc finger87 – 10923C2H2-type 1
Zinc finger115 – 13723C2H2-type 2
Zinc finger143 – 16523C2H2-type 3
Zinc finger171 – 19323C2H2-type 4

Sequences

Sequence LengthMass (Da)Tools
Q8N8Y5 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: A41841AA44CCBDE1

FASTA19822,806
        10         20         30         40         50         60 
MEKPAGRKKK TPTPREEADV QKSALREEKV SGDRKPPERP TVPRKPRTEP CLSPEDEEHV 

        70         80         90        100        110        120 
FDAFDASFKD DFEGVPVFIP FQRKKPYECS ECGRIFKHKT DHIRHQRVHT GEKPFKCAQC 

       130        140        150        160        170        180 
GKAFRHSSDV TKHQRTHTGE KPFKCGECGK AFNCGSNLLK HQKTHTGEKP YECTHCGKAF 

       190 
AYSSCLIRHQ KRHPRKKP 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney.
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK096024 mRNA. Translation: BAC04676.1.
CH471162 Genomic DNA. Translation: EAW82273.1.
CH471162 Genomic DNA. Translation: EAW82274.1.
CH471162 Genomic DNA. Translation: EAW82275.1.
BC034608 mRNA. Translation: AAH34608.1.
RefSeqNP_001258085.2. NM_001271156.2.
NP_776193.2. NM_173832.5.
UniGeneHs.668016.

3D structure databases

ProteinModelPortalQ8N8Y5.
SMRQ8N8Y5. Positions 58-198.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM74760014.

Proteomic databases

PRIDEQ8N8Y5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000330701; ENSP00000327427; ENSG00000181638.
ENST00000520584; ENSP00000430465; ENSG00000181638.
GeneID286128.
KEGGhsa:286128.
UCSCuc003yxw.4. human.

Organism-specific databases

CTD286128.
GeneCardsGC08P144331.
HGNCHGNC:26786. ZFP41.
HPAHPA056268.
neXtProtNX_Q8N8Y5.
PharmGKBPA142670529.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000234617.
HOVERGENHBG098192.
InParanoidQ8N8Y5.
OMAFTPFQRK.
PhylomeDBQ8N8Y5.
TreeFamTF337091.

Gene expression databases

BgeeQ8N8Y5.
CleanExHS_ZFP41.
GenevestigatorQ8N8Y5.

Family and domain databases

Gene3D3.30.160.60. 4 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 4 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi286128.
NextBio96001.
PROQ8N8Y5.

Entry information

Entry nameZFP41_HUMAN
AccessionPrimary (citable) accession number: Q8N8Y5
Secondary accession number(s): D3DWJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 8

Human chromosome 8: entries, gene names and cross-references to MIM