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Protein

Protein mab-21-like 3

Gene

MAB21L3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000173212-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein mab-21-like 3
Gene namesi
Name:MAB21L3
Synonyms:C1orf161
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:26787. MAB21L3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000173212.
PharmGKBiPA142672412.

Polymorphism and mutation databases

BioMutaiMAB21L3.
DMDMi147742988.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002865841 – 362Protein mab-21-like 3Add BLAST362

Proteomic databases

EPDiQ8N8X9.
PaxDbiQ8N8X9.
PRIDEiQ8N8X9.

Expressioni

Gene expression databases

BgeeiENSG00000173212.
CleanExiHS_C1orf161.
GenevisibleiQ8N8X9. HS.

Organism-specific databases

HPAiHPA046187.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
AGGF1Q6PIK73EBI-10268010,EBI-10268037
EMDP504023EBI-10268010,EBI-489887
FAM9BQ8IZU03EBI-10268010,EBI-10175124
KRTAP10-9P604113EBI-10268010,EBI-10172052
LZTS2Q9BRK45EBI-10268010,EBI-741037
MED4Q9NPJ63EBI-10268010,EBI-394607
PHC2Q8IXK03EBI-10268010,EBI-713786
STAC3Q96MF25EBI-10268010,EBI-745680

Protein-protein interaction databases

BioGridi126023. 9 interactors.
IntActiQ8N8X9. 14 interactors.
STRINGi9606.ENSP00000358512.

Structurei

3D structure databases

ProteinModelPortaliQ8N8X9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mab-21 family.Curated

Phylogenomic databases

eggNOGiKOG3963. Eukaryota.
ENOG410XNRJ. LUCA.
GeneTreeiENSGT00510000046791.
HOVERGENiHBG107559.
InParanoidiQ8N8X9.
OMAiPEGLQQW.
OrthoDBiEOG091G06D0.
PhylomeDBiQ8N8X9.
TreeFamiTF315012.

Family and domain databases

InterProiIPR024810. Mab-21_dom.
[Graphical view]
PfamiPF03281. Mab-21. 1 hit.
[Graphical view]
SMARTiSM01265. Mab-21. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N8X9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYLTVGDLE DCLLNKVDLR RQQISQAVEE VQKVVHHLTT NISNQDIRFQ
60 70 80 90 100
AVPYSDTYNE NIKVLAPSQF LVTVPIKGLA GYREAREQHW RYYTLQGTRL
110 120 130 140 150
PCPLRDPEGL QQWLEVEQFM KSLWQWHETD VNIDGDIVPA KVLLVFRKLV
160 170 180 190 200
ENAVRTCHLS GKVSLLGNRS AVWVAVETSA YQVELELVPA VEIPTTWSKK
210 220 230 240 250
ARWPRCLQRW PSQERVECIK SFGFNLLACS NYHWQLSFLR AEQVLLEQLD
260 270 280 290 300
EDGGCRRKCF QVMRHLKEDI WCPGNRPVIT SHHLQTVLFW TCEKYPHFKD
310 320 330 340 350
WQVFSKAFLR LVRKLHKCVS QHFLKHYFVR NSNLFQCTNP TELDTVAQKL
360
ATFLKNPQIG PP
Length:362
Mass (Da):42,357
Last modified:May 15, 2007 - v2
Checksum:iFE18C96B4E90CE42
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti338T → A in BAC04682 (PubMed:14702039).Curated1
Sequence conflicti338T → A in AAI28150 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096035 mRNA. Translation: BAC04682.1.
AL121982 Genomic DNA. Translation: CAI19381.1.
BC128148 mRNA. Translation: AAI28149.1.
BC128149 mRNA. Translation: AAI28150.1.
CCDSiCCDS886.1.
RefSeqiNP_689580.2. NM_152367.2.
XP_011538925.1. XM_011540623.2.
XP_011538927.1. XM_011540625.2.
XP_011538928.1. XM_011540626.2.
XP_016855749.1. XM_017000260.1.
UniGeneiHs.376194.

Genome annotation databases

EnsembliENST00000369500; ENSP00000358512; ENSG00000173212.
GeneIDi126868.
KEGGihsa:126868.
UCSCiuc001egc.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096035 mRNA. Translation: BAC04682.1.
AL121982 Genomic DNA. Translation: CAI19381.1.
BC128148 mRNA. Translation: AAI28149.1.
BC128149 mRNA. Translation: AAI28150.1.
CCDSiCCDS886.1.
RefSeqiNP_689580.2. NM_152367.2.
XP_011538925.1. XM_011540623.2.
XP_011538927.1. XM_011540625.2.
XP_011538928.1. XM_011540626.2.
XP_016855749.1. XM_017000260.1.
UniGeneiHs.376194.

3D structure databases

ProteinModelPortaliQ8N8X9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126023. 9 interactors.
IntActiQ8N8X9. 14 interactors.
STRINGi9606.ENSP00000358512.

Polymorphism and mutation databases

BioMutaiMAB21L3.
DMDMi147742988.

Proteomic databases

EPDiQ8N8X9.
PaxDbiQ8N8X9.
PRIDEiQ8N8X9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000369500; ENSP00000358512; ENSG00000173212.
GeneIDi126868.
KEGGihsa:126868.
UCSCiuc001egc.1. human.

Organism-specific databases

CTDi126868.
GeneCardsiMAB21L3.
HGNCiHGNC:26787. MAB21L3.
HPAiHPA046187.
neXtProtiNX_Q8N8X9.
OpenTargetsiENSG00000173212.
PharmGKBiPA142672412.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3963. Eukaryota.
ENOG410XNRJ. LUCA.
GeneTreeiENSGT00510000046791.
HOVERGENiHBG107559.
InParanoidiQ8N8X9.
OMAiPEGLQQW.
OrthoDBiEOG091G06D0.
PhylomeDBiQ8N8X9.
TreeFamiTF315012.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000173212-MONOMER.

Miscellaneous databases

GenomeRNAii126868.
PROiQ8N8X9.

Gene expression databases

BgeeiENSG00000173212.
CleanExiHS_C1orf161.
GenevisibleiQ8N8X9. HS.

Family and domain databases

InterProiIPR024810. Mab-21_dom.
[Graphical view]
PfamiPF03281. Mab-21. 1 hit.
[Graphical view]
SMARTiSM01265. Mab-21. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMB213_HUMAN
AccessioniPrimary (citable) accession number: Q8N8X9
Secondary accession number(s): Q5TDL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: November 30, 2016
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.