Q8N8I0 (SAM12_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sterile alpha motif domain-containing protein 12
Short name=SAM domain-containing protein 12

Gene names

Name:

SAMD12

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SAM (sterile alpha motif) domain.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Sterile alpha motif domain-containing protein 12		PRO_0000279502
Regions
	Domain	77 – 143	67	SAM
Experimental info
	Sequence conflict	172	1	T → A in BAC04861. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q8N8I0 [UniParc]. Last modified May 1, 2007. Version 2. Checksum: AF6C7991A96B344D	FASTA	201	22,907
	10 20 30 40 50 60 MAVEALHCGL NPRGIDHPAH AEGIKLQIEG EGVESQSIKN KNFQKVPDQK GTPKRLQAEA 70 80 90 100 110 120 ETAKSATVKL SKPVALWTQQ DVCKWLKKHC PNQYQIYSES FKQHDITGRA LLRLTDKKLE 130 140 150 160 170 180 RMGIAQENLR QHILQQVLQL KVREEVRNLQ LLTQGTLLLP DGWMDGEIRR KTTLLLGQTG 190 200 VRENLLLFLH RISIIENSIQ I

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Prostate.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK096777 mRNA. Translation: BAC04861.1. BC121818 mRNA. Translation: AAI21819.1. BC124554 mRNA. Translation: AAI24555.1.
IPI	IPI00410332.
RefSeq	NP_997389.2. NM_207506.2.
UniGene	Hs.359393. Hs.701196.
3D structure databases
ProteinModelPortal	Q8N8I0.
SMR	Q8N8I0. Positions 71-154.
ModBase	Search...
Polymorphism databases
DMDM	146345509.
Proteomic databases
PRIDE	Q8N8I0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000314727; ENSP00000314173; ENSG00000177570.
GeneID	401474.
KEGG	hsa:401474.
NMPDR	fig|9606.3.peg.30671.
UCSC	uc003yom.2. human.
Organism-specific databases
CTD	401474.
GeneCards	GC08M119270.
HGNC	HGNC:31750. SAMD12.
HPA	HPA024634.
neXtProt	NX_Q8N8I0.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG09566.
GeneTree	ENSGT00390000008161.
HOGENOM	HBG716069.
HOVERGEN	HBG093930.
PhylomeDB	Q8N8I0.
Gene expression databases
ArrayExpress	Q8N8I0.
Bgee	Q8N8I0.
CleanEx	HS_SAMD12.
Genevestigator	Q8N8I0.
Family and domain databases
InterPro	IPR001660. SAM. IPR013761. SAM/pointed. IPR011510. SAM_2. [Graphical view]
Gene3D	G3DSA:1.10.150.50. SAM_type. 1 hit.
Pfam	PF07647. SAM_2. 1 hit. [Graphical view]
SMART	SM00454. SAM. 1 hit. [Graphical view]
SUPFAM	SSF47769. SAM_homology. 1 hit.
PROSITE	PS50105. SAM_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	106880.

Entry information

Entry name

SAM12_HUMAN

Accession

Primary (citable) accession number: Q8N8I0
Secondary accession number(s): Q0P502

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 6, 2007
Last sequence update:	May 1, 2007
Last modified:	January 25, 2012
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.