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Protein
Submitted name:

Exostoses (Multiple)-like 2, isoform CRA_b

Gene

EXTL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

CAZyiGT64. Glycosyltransferase Family 64.

Names & Taxonomyi

Protein namesi
Submitted name:
Exostoses (Multiple)-like 2, isoform CRA_bImported
Submitted name:
cDNA FLJ39595 fis, clone SKNSH2001931, highly similar to ExostosesImported
Gene namesi
Name:EXTL2Imported
ORF Names:hCG_32848Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 43HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27928.

PTM / Processingi

Proteomic databases

PRIDEiQ8N8F1.

Expressioni

Gene expression databases

BgeeiENSG00000162694.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359131.

Structurei

3D structure databases

ProteinModelPortaliQ8N8F1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 320Glyco_transf_64InterPro annotationAdd BLAST255

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1022. Eukaryota.
ENOG410XQYV. LUCA.
HOVERGENiHBG051525.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR015338. EXT_C.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF09258. Glyco_transf_64. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8N8F1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRCCHICKLP GRVMGIRVLR LSLVVILVLL LVAGALTALL PSVKEDKMLM
60 70 80 90 100
LRREIKSQGK STMDSFTLIM QTYNRTDLLL KLLNHYQAVP NLHKVIVVWN
110 120 130 140 150
NIGEKAPDEL WNSLGPHPIP VIFKQQTANR MRNRLQVFPE LETNVLMVDD
160 170 180 190 200
DTLISTPDLV FAFSVWQQFP DQIVGFVPRK HVSTSSGIYS YGSFEMQAPG
210 220 230 240 250
SGNGDQYSMV LIGASFFNSK YLELFQRQPA AVHALIDDTQ NCDDIAMNFI
260 270 280 290 300
IAKHIGKTSG IFVKPVNMDN LEKETNSGYS GMWHRAEHAL QRSYCINKLV
310 320
NIYDSMPLRY SNIMISQFGF PYANYKRKI
Length:329
Mass (Da):37,395
Last modified:October 1, 2002 - v1
Checksum:i7CE07064474BE340
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096914 mRNA. Translation: BAC04893.1.
CH471097 Genomic DNA. Translation: EAW72947.1.
RefSeqiNP_001248369.1. NM_001261440.1.
XP_016856140.1. XM_017000651.1.
UniGeneiHs.357637.

Genome annotation databases

GeneIDi2135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096914 mRNA. Translation: BAC04893.1.
CH471097 Genomic DNA. Translation: EAW72947.1.
RefSeqiNP_001248369.1. NM_001261440.1.
XP_016856140.1. XM_017000651.1.
UniGeneiHs.357637.

3D structure databases

ProteinModelPortaliQ8N8F1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359131.

Protein family/group databases

CAZyiGT64. Glycosyltransferase Family 64.

Proteomic databases

PRIDEiQ8N8F1.

Protocols and materials databases

DNASUi2135.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2135.

Organism-specific databases

CTDi2135.
PharmGKBiPA27928.

Phylogenomic databases

eggNOGiKOG1022. Eukaryota.
ENOG410XQYV. LUCA.
HOVERGENiHBG051525.

Miscellaneous databases

ChiTaRSiEXTL2. human.
GenomeRNAii2135.

Gene expression databases

BgeeiENSG00000162694.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR015338. EXT_C.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF09258. Glyco_transf_64. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8N8F1_HUMAN
AccessioniPrimary (citable) accession number: Q8N8F1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.