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Protein

Tubulin polyglutamylase TTLL6

Gene

TTLL6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS/MB21D1, leading to impair the DNA-binding activity of CGAS/MB21D1.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei216 – 2161ATPBy similarity
Binding sitei218 – 2181ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi203 – 2064ATP bindingBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin polyglutamylase TTLL6 (EC:6.-.-.-)
Alternative name(s):
Tubulin--tyrosine ligase-like protein 6
Gene namesi
Name:TTLL6Imported
Synonyms:TTL.61 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:26664. TTLL6.

Subcellular locationi

GO - Cellular componenti

  • ciliary basal body Source: UniProtKB
  • cytoplasm Source: UniProtKB-KW
  • microtubule Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Microtubule

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi396 – 3983KKK → EEE: Decreased binding to microtubules and polyglutamylase activity; when associated with E-416 and E-419. 1 Publication
Mutagenesisi416 – 4161R → E: Decreased binding to microtubules and polyglutamylase activity; when associated with 396-E--E-398 and E-419. 1 Publication
Mutagenesisi419 – 4191R → E: Decreased binding to microtubules and polyglutamylase activity; when associated with 396-E--E-398 and E-416. 1 Publication

Organism-specific databases

PharmGKBiPA143485662.

Polymorphism and mutation databases

BioMutaiTTLL6.
DMDMi172045779.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 843843Tubulin polyglutamylase TTLL6PRO_0000326160Add
BLAST

Proteomic databases

EPDiQ8N841.
PaxDbiQ8N841.
PRIDEiQ8N841.

PTM databases

iPTMnetiQ8N841.
PhosphoSiteiQ8N841.

Expressioni

Gene expression databases

BgeeiENSG00000170703.
ExpressionAtlasiQ8N841. baseline and differential.
GenevisibleiQ8N841. HS.

Organism-specific databases

HPAiHPA052397.

Interactioni

Subunit structurei

Found in a complex with CEP41.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi129751. 3 interactions.
IntActiQ8N841. 3 interactions.
STRINGi9606.ENSP00000377043.

Structurei

3D structure databases

ProteinModelPortaliQ8N841.
SMRiQ8N841. Positions 61-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini58 – 401344TTLPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni372 – 45180c-MTBD region1 PublicationAdd
BLAST

Domaini

The flexible c-MTBD (cationic microtubule binding domain) region mediates binding to microtubules. It is positively charged and becomes ordered when bound to microtubules: it interacts with a negatively charged patch on tubulin. The presence of positive charges in the c-MTBD region is essential for proper binding.By similarity1 Publication

Sequence similaritiesi

Belongs to the tubulin--tyrosine ligase family.Sequence analysis
Contains 1 TTL domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2158. Eukaryota.
ENOG410XNWC. LUCA.
HOVERGENiHBG108618.
InParanoidiQ8N841.
KOiK16582.
OrthoDBiEOG091G01RO.
PhylomeDBiQ8N841.
TreeFamiTF313087.

Family and domain databases

InterProiIPR004344. TTL/TTLL_fam.
IPR027754. TTLL6.
[Graphical view]
PANTHERiPTHR12241:SF96. PTHR12241:SF96. 1 hit.
PfamiPF03133. TTL. 1 hit.
[Graphical view]
PROSITEiPS51221. TTL. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 11 Publication (identifier: Q8N841-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPQCPTLESQ EGENSEEKGD SSKEDPKETV ALAFVRENPG AQNGLQNAQQ
60 70 80 90 100
QGKKKRKKKR LVINLSSCRY ESVRRAAQQY GFREGGEDDD WTLYWTDYSV
110 120 130 140 150
SLERVMEMKS YQKINHFPGM SEICRKDLLA RNMSRMLKMF PKDFRFFPRT
160 170 180 190 200
WCLPADWGDL QTYSRSRKNK TYICKPDSGC QGKGIFITRT VKEIKPGEDM
210 220 230 240 250
ICQLYISKPF IIDGFKFDLR IYVLVTSCDP LRIFVYNEGL ARFATTSYSR
260 270 280 290 300
PCTDNLDDIC MHLTNYSINK HSSNFSRDAH SGSKRKLSTF SAYLEDHSYN
310 320 330 340 350
VEQIWRDIED VIIKTLISAH PIIRHNYHTC FPNHTLNSAC FEILGFDILL
360 370 380 390 400
DHKLKPWLLE VNHSPSFSTD SRLDKEVKDG LLYDTLVLIN LESCDKKKVL
410 420 430 440 450
EEERQRGQFL QQCCSREMRI EEAKGFRAVQ LKKTETYEKE NCGGFRLIYP
460 470 480 490 500
SLNSEKYEKF FQDNNSLFQN TVASRAREEY ARQLIQELRL KREKKPFQMK
510 520 530 540 550
KKVEMQGESA GEQVRKKGMR GWQQKQQQKD KAATQASKQY IQPLTLVSYT
560 570 580 590 600
PDLLLSVRGE RKNETDSSLN QEAPTEEASS VFPKLTSAKP FSSLPDLRNI
610 620 630 640 650
NLSSSKLEPS KPNFSIKEAK SASAVNVFTG TVHLTSVETT PESTTQLSIS
660 670 680 690 700
PKSPPTLAVT ASSEYSGPET DRVVSFKCKK QQTPPHLTQK KMLKSFLPTK
710 720 730 740 750
SKSFWESPNT NWTLLKSDMN KPHLISELLT KLQLSGKLSF FPAHYNPKLG
760 770 780 790 800
MNNLSQNPSL PGECHSRSDS SGEKRQLDVS SLLLQSPQSY NVTLRDLLVI
810 820 830 840
ATPAQLDPRP CRSHASAMRD PCMQDQEAYS HCLISGQKGC ERS
Length:843
Mass (Da):96,401
Last modified:March 18, 2008 - v2
Checksum:iD1C24002A551D54D
GO
Isoform 22 Publications (identifier: Q8N841-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-274: Missing.
     275-284: FSRDAHSGSK → MEGCLGVAEL

Show »
Length:569
Mass (Da):64,547
Checksum:i0E5AE7873AA3E5E3
GO

Sequence cautioni

The sequence BAC04066 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti664 – 6641E → D.2 Publications
Corresponds to variant rs2032844 [ dbSNP | Ensembl ].
VAR_039993
Isoform 22 Publications (identifier: Q8N841-2)
Natural varianti9 – 91E → V.1 Publication
Corresponds to variant rs17853181 [ dbSNP | Ensembl ].

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 274274Missing in isoform 2. 2 PublicationsVSP_052727Add
BLAST
Alternative sequencei275 – 28410FSRDAHSGSK → MEGCLGVAEL in isoform 2. 2 PublicationsVSP_052728

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY898275 Genomic DNA. Translation: AAY28091.1.
AY898276 Genomic DNA. Translation: AAY28092.1.
AY898277 Genomic DNA. Translation: AAY28093.1.
AY898278 Genomic DNA. Translation: AAY28094.1.
AY898279 Genomic DNA. Translation: AAY28095.1.
AY898280 Genomic DNA. Translation: AAY28096.1.
AY898281 Genomic DNA. Translation: AAY28097.1.
AY898282 Genomic DNA. Translation: AAY28098.1.
AY898283 Genomic DNA. Translation: AAY28099.1.
AY898284 Genomic DNA. Translation: AAY28100.1.
AY898285 Genomic DNA. Translation: AAY28101.1.
AY898286 Genomic DNA. Translation: AAY28102.1.
AY898287 Genomic DNA. Translation: AAY28103.1.
AY898288 Genomic DNA. Translation: AAY28104.1.
AY898289 Genomic DNA. Translation: AAY28105.1.
AY898290 Genomic DNA. Translation: AAY28106.1.
AY898291 Genomic DNA. Translation: AAY28107.1.
AY898292 Genomic DNA. Translation: AAY28108.1.
AY898293 Genomic DNA. Translation: AAY28109.1.
AY898294 Genomic DNA. Translation: AAY28110.1.
AY898295 Genomic DNA. Translation: AAY28111.1.
AY898296 Genomic DNA. Translation: AAY28112.1.
AY898297 Genomic DNA. Translation: AAY28113.1.
AY898298 Genomic DNA. Translation: AAY28114.1.
AY898299 Genomic DNA. Translation: AAY28115.1.
AY898300 Genomic DNA. Translation: AAY28116.1.
AY898301 Genomic DNA. Translation: AAY28117.1.
AY898302 Genomic DNA. Translation: AAY28118.1.
AY898303 Genomic DNA. Translation: AAY28119.1.
AY898304 Genomic DNA. Translation: AAY28120.1.
AY898305 Genomic DNA. Translation: AAY28121.1.
AY898306 Genomic DNA. Translation: AAY28122.1.
AY898307 Genomic DNA. Translation: AAY28123.1.
AY898308 Genomic DNA. Translation: AAY28124.1.
AY898309 Genomic DNA. Translation: AAY28125.1.
AY898317 Genomic DNA. Translation: AAX86172.1.
AY898318 Genomic DNA. Translation: AAX86173.1.
AY898319 Genomic DNA. Translation: AAX86174.1.
AY898320 Genomic DNA. Translation: AAX86175.1.
AY898321 Genomic DNA. Translation: AAX86176.1.
AY898322 Genomic DNA. Translation: AAX86177.1.
AY898323 Genomic DNA. Translation: AAX86178.1.
AY898324 Genomic DNA. Translation: AAX86179.1.
AY898325 Genomic DNA. Translation: AAX86180.1.
AY898326 Genomic DNA. Translation: AAX86181.1.
AY898327 Genomic DNA. Translation: AAX86182.1.
AY898328 Genomic DNA. Translation: AAX86183.1.
AY898329 Genomic DNA. Translation: AAX86184.1.
AY898330 Genomic DNA. Translation: AAX86185.1.
AY898331 Genomic DNA. Translation: AAX86186.1.
AY898332 Genomic DNA. Translation: AAX86187.1.
AY898333 Genomic DNA. Translation: AAX86188.1.
AY898334 Genomic DNA. Translation: AAX86189.1.
AY898335 Genomic DNA. Translation: AAX86190.1.
AY898336 Genomic DNA. Translation: AAX86191.1.
AY898337 Genomic DNA. Translation: AAX86192.1.
AY898338 Genomic DNA. Translation: AAX86193.1.
AY898339 Genomic DNA. Translation: AAX86194.1.
AY898340 Genomic DNA. Translation: AAX86195.1.
AY898341 Genomic DNA. Translation: AAX86196.1.
AY898342 Genomic DNA. Translation: AAX86197.1.
AY898343 Genomic DNA. Translation: AAX86198.1.
AY898344 Genomic DNA. Translation: AAX86199.1.
AY898345 Genomic DNA. Translation: AAX86200.1.
AY898346 Genomic DNA. Translation: AAX86201.1.
AY898347 Genomic DNA. Translation: AAX86202.1.
AY898348 Genomic DNA. Translation: AAX86203.1.
AY898349 Genomic DNA. Translation: AAX86204.1.
AY898350 Genomic DNA. Translation: AAX86205.1.
AY898351 Genomic DNA. Translation: AAX86206.1.
AY898359 Genomic DNA. Translation: AAX86214.1.
AY898360 Genomic DNA. Translation: AAX86215.1.
AY898361 Genomic DNA. Translation: AAX86216.1.
AY898362 Genomic DNA. Translation: AAX86217.1.
AY898363 Genomic DNA. Translation: AAX86218.1.
AY898364 Genomic DNA. Translation: AAX86219.1.
AY898365 Genomic DNA. Translation: AAX86220.1.
AY898366 Genomic DNA. Translation: AAX86221.1.
AY898367 Genomic DNA. Translation: AAX86222.1.
AY898368 Genomic DNA. Translation: AAX86223.1.
AY898369 Genomic DNA. Translation: AAX86224.1.
AY898370 Genomic DNA. Translation: AAX86225.1.
AY898371 Genomic DNA. Translation: AAX86226.1.
AY898372 Genomic DNA. Translation: AAX86227.1.
AY898373 Genomic DNA. Translation: AAX86228.1.
AY898374 Genomic DNA. Translation: AAX86229.1.
AY898375 Genomic DNA. Translation: AAX86230.1.
AY898376 Genomic DNA. Translation: AAX86231.1.
AY898377 Genomic DNA. Translation: AAX86232.1.
AY898378 Genomic DNA. Translation: AAX86233.1.
AY898379 Genomic DNA. Translation: AAX86234.1.
AY898380 Genomic DNA. Translation: AAX86235.1.
AY898381 Genomic DNA. Translation: AAX86236.1.
AY898382 Genomic DNA. Translation: AAX86237.1.
AY898383 Genomic DNA. Translation: AAX86238.1.
AY898384 Genomic DNA. Translation: AAX86239.1.
AY898385 Genomic DNA. Translation: AAX86240.1.
AY898386 Genomic DNA. Translation: AAX86241.1.
AY898387 Genomic DNA. Translation: AAX86242.1.
AY898388 Genomic DNA. Translation: AAX86243.1.
AY898389 Genomic DNA. Translation: AAX86244.1.
AY898390 Genomic DNA. Translation: AAX86245.1.
AY898391 Genomic DNA. Translation: AAX86246.1.
AY898392 Genomic DNA. Translation: AAX86247.1.
AY898393 Genomic DNA. Translation: AAX86248.1.
AY898401 Genomic DNA. Translation: AAX86256.1.
AY898402 Genomic DNA. Translation: AAX86257.1.
AY898403 Genomic DNA. Translation: AAX86258.1.
AY898404 Genomic DNA. Translation: AAX86259.1.
AY898405 Genomic DNA. Translation: AAX86260.1.
AY898406 Genomic DNA. Translation: AAX86261.1.
AY898407 Genomic DNA. Translation: AAX86262.1.
AY898408 Genomic DNA. Translation: AAX86263.1.
AY898409 Genomic DNA. Translation: AAX86264.1.
AY898410 Genomic DNA. Translation: AAX86265.1.
AY898411 Genomic DNA. Translation: AAX86266.1.
AY898412 Genomic DNA. Translation: AAX86267.1.
AY898413 Genomic DNA. Translation: AAX86268.1.
AY898414 Genomic DNA. Translation: AAX86269.1.
AY898415 Genomic DNA. Translation: AAX86270.1.
AY898416 Genomic DNA. Translation: AAX86271.1.
AY898417 Genomic DNA. Translation: AAX86272.1.
AY898418 Genomic DNA. Translation: AAX86273.1.
AY898419 Genomic DNA. Translation: AAX86274.1.
AY898420 Genomic DNA. Translation: AAX86275.1.
AY898421 Genomic DNA. Translation: AAX86276.1.
AY898422 Genomic DNA. Translation: AAX86277.1.
AY898423 Genomic DNA. Translation: AAX86278.1.
AY898424 Genomic DNA. Translation: AAX86279.1.
AY898425 Genomic DNA. Translation: AAX86280.1.
AY898426 Genomic DNA. Translation: AAX86281.1.
AY898427 Genomic DNA. Translation: AAX86282.1.
AY898428 Genomic DNA. Translation: AAX86283.1.
AY898429 Genomic DNA. Translation: AAX86284.1.
AY898430 Genomic DNA. Translation: AAX86285.1.
AY898431 Genomic DNA. Translation: AAX86286.1.
AY898432 Genomic DNA. Translation: AAX86287.1.
AY898433 Genomic DNA. Translation: AAX86288.1.
AY898434 Genomic DNA. Translation: AAX86289.1.
AY898435 Genomic DNA. Translation: AAX86290.1.
AY898443 Genomic DNA. Translation: AAX86298.1.
AY898444 Genomic DNA. Translation: AAX86299.1.
AY898445 Genomic DNA. Translation: AAX86300.1.
AY898446 Genomic DNA. Translation: AAX86301.1.
AY898447 Genomic DNA. Translation: AAX86302.1.
AY898448 Genomic DNA. Translation: AAX86303.1.
AY898449 Genomic DNA. Translation: AAX86304.1.
AY898450 Genomic DNA. Translation: AAX86305.1.
AY898451 Genomic DNA. Translation: AAX86306.1.
AY898452 Genomic DNA. Translation: AAX86307.1.
AY898453 Genomic DNA. Translation: AAX86308.1.
AY898454 Genomic DNA. Translation: AAX86309.1.
AY898455 Genomic DNA. Translation: AAX86310.1.
AY898456 Genomic DNA. Translation: AAX86311.1.
AY898457 Genomic DNA. Translation: AAX86312.1.
AY898458 Genomic DNA. Translation: AAX86313.1.
AY898459 Genomic DNA. Translation: AAX86314.1.
AY898460 Genomic DNA. Translation: AAX86315.1.
AY898461 Genomic DNA. Translation: AAX86316.1.
AY898462 Genomic DNA. Translation: AAX86317.1.
AY898463 Genomic DNA. Translation: AAX86318.1.
AY898464 Genomic DNA. Translation: AAX86319.1.
AY898465 Genomic DNA. Translation: AAX86320.1.
AY898466 Genomic DNA. Translation: AAX86321.1.
AY898467 Genomic DNA. Translation: AAX86322.1.
AY898468 Genomic DNA. Translation: AAX86323.1.
AY898469 Genomic DNA. Translation: AAX86324.1.
AY898470 Genomic DNA. Translation: AAX86325.1.
AY898471 Genomic DNA. Translation: AAX86326.1.
AY898472 Genomic DNA. Translation: AAX86327.1.
AY898473 Genomic DNA. Translation: AAX86328.1.
AY898474 Genomic DNA. Translation: AAX86329.1.
AY898475 Genomic DNA. Translation: AAX86330.1.
AY898476 Genomic DNA. Translation: AAX86331.1.
AY898477 Genomic DNA. Translation: AAX86332.1.
AY898485 Genomic DNA. Translation: AAX86340.1.
AY898486 Genomic DNA. Translation: AAX86341.1.
AY898487 Genomic DNA. Translation: AAX86342.1.
AY898488 Genomic DNA. Translation: AAX86343.1.
AY898489 Genomic DNA. Translation: AAX86344.1.
AY898490 Genomic DNA. Translation: AAX86345.1.
AY898491 Genomic DNA. Translation: AAX86346.1.
AY898492 Genomic DNA. Translation: AAX86347.1.
AY898493 Genomic DNA. Translation: AAX86348.1.
AY898494 Genomic DNA. Translation: AAX86349.1.
AY898495 Genomic DNA. Translation: AAX86350.1.
AY898496 Genomic DNA. Translation: AAX86351.1.
AY898497 Genomic DNA. Translation: AAX86352.1.
AY898498 Genomic DNA. Translation: AAX86353.1.
AY898499 Genomic DNA. Translation: AAX86354.1.
AY898500 Genomic DNA. Translation: AAX86355.1.
AY898501 Genomic DNA. Translation: AAX86356.1.
AY898502 Genomic DNA. Translation: AAX86357.1.
AY898503 Genomic DNA. Translation: AAX86358.1.
AY898504 Genomic DNA. Translation: AAX86359.1.
AY898505 Genomic DNA. Translation: AAX86360.1.
AY898506 Genomic DNA. Translation: AAX86361.1.
AY898507 Genomic DNA. Translation: AAX86362.1.
AY898508 Genomic DNA. Translation: AAX86363.1.
AY898509 Genomic DNA. Translation: AAX86364.1.
AY898510 Genomic DNA. Translation: AAX86365.1.
AY898511 Genomic DNA. Translation: AAX86366.1.
AY898512 Genomic DNA. Translation: AAX86367.1.
AY898513 Genomic DNA. Translation: AAX86368.1.
AY898514 Genomic DNA. Translation: AAX86369.1.
AY898515 Genomic DNA. Translation: AAX86370.1.
AY898516 Genomic DNA. Translation: AAX86371.1.
AY898517 Genomic DNA. Translation: AAX86372.1.
AY898518 Genomic DNA. Translation: AAX86373.1.
AY898519 Genomic DNA. Translation: AAX86374.1.
AY898527 Genomic DNA. Translation: AAX86382.1.
AY898528 Genomic DNA. Translation: AAX86383.1.
AY898529 Genomic DNA. Translation: AAX86384.1.
AY898530 Genomic DNA. Translation: AAX86385.1.
AY898531 Genomic DNA. Translation: AAX86386.1.
AY898532 Genomic DNA. Translation: AAX86387.1.
AY898533 Genomic DNA. Translation: AAX86388.1.
AY898534 Genomic DNA. Translation: AAX86389.1.
AY898535 Genomic DNA. Translation: AAX86390.1.
AY898536 Genomic DNA. Translation: AAX86391.1.
AY898537 Genomic DNA. Translation: AAX86392.1.
AY898538 Genomic DNA. Translation: AAX86393.1.
AY898539 Genomic DNA. Translation: AAX86394.1.
AY898540 Genomic DNA. Translation: AAX86395.1.
AY898541 Genomic DNA. Translation: AAX86396.1.
AY898542 Genomic DNA. Translation: AAX86397.1.
AY898543 Genomic DNA. Translation: AAX86398.1.
AY898544 Genomic DNA. Translation: AAX86399.1.
AY898545 Genomic DNA. Translation: AAX86400.1.
AY898546 Genomic DNA. Translation: AAX86401.1.
AY898547 Genomic DNA. Translation: AAX86402.1.
AY898548 Genomic DNA. Translation: AAX86403.1.
AY898549 Genomic DNA. Translation: AAX86404.1.
AY898550 Genomic DNA. Translation: AAX86405.1.
AY898551 Genomic DNA. Translation: AAX86406.1.
AY898552 Genomic DNA. Translation: AAX86407.1.
AY898553 Genomic DNA. Translation: AAX86408.1.
AY898554 Genomic DNA. Translation: AAX86409.1.
AY898555 Genomic DNA. Translation: AAX86410.1.
AY898556 Genomic DNA. Translation: AAX86411.1.
AY898557 Genomic DNA. Translation: AAX86412.1.
AY898558 Genomic DNA. Translation: AAX86413.1.
AY898559 Genomic DNA. Translation: AAX86414.1.
AY898560 Genomic DNA. Translation: AAX86415.1.
AY898561 Genomic DNA. Translation: AAX86416.1.
AY898569 Genomic DNA. Translation: AAX86424.1.
AY898570 Genomic DNA. Translation: AAX86425.1.
AY898571 Genomic DNA. Translation: AAX86426.1.
AY898572 Genomic DNA. Translation: AAX86427.1.
AY898573 Genomic DNA. Translation: AAX86428.1.
AY898574 Genomic DNA. Translation: AAX86429.1.
AY898575 Genomic DNA. Translation: AAX86430.1.
AY898576 Genomic DNA. Translation: AAX86431.1.
AY898577 Genomic DNA. Translation: AAX86432.1.
AY898578 Genomic DNA. Translation: AAX86433.1.
AY898579 Genomic DNA. Translation: AAX86434.1.
AY898580 Genomic DNA. Translation: AAX86435.1.
AY898581 Genomic DNA. Translation: AAX86436.1.
AY898582 Genomic DNA. Translation: AAX86437.1.
AY898583 Genomic DNA. Translation: AAX86438.1.
AY898584 Genomic DNA. Translation: AAX86439.1.
AY898585 Genomic DNA. Translation: AAX86440.1.
AY898586 Genomic DNA. Translation: AAX86441.1.
AY898587 Genomic DNA. Translation: AAX86442.1.
AY898588 Genomic DNA. Translation: AAX86443.1.
AY898589 Genomic DNA. Translation: AAX86444.1.
AY898590 Genomic DNA. Translation: AAX86445.1.
AY898591 Genomic DNA. Translation: AAX86446.1.
AY898592 Genomic DNA. Translation: AAX86447.1.
AY898593 Genomic DNA. Translation: AAX86448.1.
AY898594 Genomic DNA. Translation: AAX86449.1.
AY898595 Genomic DNA. Translation: AAX86450.1.
AY898596 Genomic DNA. Translation: AAX86451.1.
AY898597 Genomic DNA. Translation: AAX86452.1.
AY898598 Genomic DNA. Translation: AAX86453.1.
AY898599 Genomic DNA. Translation: AAX86454.1.
AY898600 Genomic DNA. Translation: AAX86455.1.
AY898601 Genomic DNA. Translation: AAX86456.1.
AY898602 Genomic DNA. Translation: AAX86457.1.
AY898603 Genomic DNA. Translation: AAX86458.1.
AK093127 mRNA. Translation: BAC04066.1. Different initiation.
AK302952 mRNA. Translation: BAG64107.1.
AC068531 Genomic DNA. No translation available.
BC033563 mRNA. Translation: AAH33563.1.
RefSeqiNP_001124390.1. NM_001130918.1.
NP_775894.2. NM_173623.3.
UniGeneiHs.91930.

Genome annotation databases

EnsembliENST00000393382; ENSP00000377043; ENSG00000170703.
ENST00000433608; ENSP00000399211; ENSG00000170703.
GeneIDi284076.
KEGGihsa:284076.
UCSCiuc002iob.4. human. [Q8N841-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY898275 Genomic DNA. Translation: AAY28091.1.
AY898276 Genomic DNA. Translation: AAY28092.1.
AY898277 Genomic DNA. Translation: AAY28093.1.
AY898278 Genomic DNA. Translation: AAY28094.1.
AY898279 Genomic DNA. Translation: AAY28095.1.
AY898280 Genomic DNA. Translation: AAY28096.1.
AY898281 Genomic DNA. Translation: AAY28097.1.
AY898282 Genomic DNA. Translation: AAY28098.1.
AY898283 Genomic DNA. Translation: AAY28099.1.
AY898284 Genomic DNA. Translation: AAY28100.1.
AY898285 Genomic DNA. Translation: AAY28101.1.
AY898286 Genomic DNA. Translation: AAY28102.1.
AY898287 Genomic DNA. Translation: AAY28103.1.
AY898288 Genomic DNA. Translation: AAY28104.1.
AY898289 Genomic DNA. Translation: AAY28105.1.
AY898290 Genomic DNA. Translation: AAY28106.1.
AY898291 Genomic DNA. Translation: AAY28107.1.
AY898292 Genomic DNA. Translation: AAY28108.1.
AY898293 Genomic DNA. Translation: AAY28109.1.
AY898294 Genomic DNA. Translation: AAY28110.1.
AY898295 Genomic DNA. Translation: AAY28111.1.
AY898296 Genomic DNA. Translation: AAY28112.1.
AY898297 Genomic DNA. Translation: AAY28113.1.
AY898298 Genomic DNA. Translation: AAY28114.1.
AY898299 Genomic DNA. Translation: AAY28115.1.
AY898300 Genomic DNA. Translation: AAY28116.1.
AY898301 Genomic DNA. Translation: AAY28117.1.
AY898302 Genomic DNA. Translation: AAY28118.1.
AY898303 Genomic DNA. Translation: AAY28119.1.
AY898304 Genomic DNA. Translation: AAY28120.1.
AY898305 Genomic DNA. Translation: AAY28121.1.
AY898306 Genomic DNA. Translation: AAY28122.1.
AY898307 Genomic DNA. Translation: AAY28123.1.
AY898308 Genomic DNA. Translation: AAY28124.1.
AY898309 Genomic DNA. Translation: AAY28125.1.
AY898317 Genomic DNA. Translation: AAX86172.1.
AY898318 Genomic DNA. Translation: AAX86173.1.
AY898319 Genomic DNA. Translation: AAX86174.1.
AY898320 Genomic DNA. Translation: AAX86175.1.
AY898321 Genomic DNA. Translation: AAX86176.1.
AY898322 Genomic DNA. Translation: AAX86177.1.
AY898323 Genomic DNA. Translation: AAX86178.1.
AY898324 Genomic DNA. Translation: AAX86179.1.
AY898325 Genomic DNA. Translation: AAX86180.1.
AY898326 Genomic DNA. Translation: AAX86181.1.
AY898327 Genomic DNA. Translation: AAX86182.1.
AY898328 Genomic DNA. Translation: AAX86183.1.
AY898329 Genomic DNA. Translation: AAX86184.1.
AY898330 Genomic DNA. Translation: AAX86185.1.
AY898331 Genomic DNA. Translation: AAX86186.1.
AY898332 Genomic DNA. Translation: AAX86187.1.
AY898333 Genomic DNA. Translation: AAX86188.1.
AY898334 Genomic DNA. Translation: AAX86189.1.
AY898335 Genomic DNA. Translation: AAX86190.1.
AY898336 Genomic DNA. Translation: AAX86191.1.
AY898337 Genomic DNA. Translation: AAX86192.1.
AY898338 Genomic DNA. Translation: AAX86193.1.
AY898339 Genomic DNA. Translation: AAX86194.1.
AY898340 Genomic DNA. Translation: AAX86195.1.
AY898341 Genomic DNA. Translation: AAX86196.1.
AY898342 Genomic DNA. Translation: AAX86197.1.
AY898343 Genomic DNA. Translation: AAX86198.1.
AY898344 Genomic DNA. Translation: AAX86199.1.
AY898345 Genomic DNA. Translation: AAX86200.1.
AY898346 Genomic DNA. Translation: AAX86201.1.
AY898347 Genomic DNA. Translation: AAX86202.1.
AY898348 Genomic DNA. Translation: AAX86203.1.
AY898349 Genomic DNA. Translation: AAX86204.1.
AY898350 Genomic DNA. Translation: AAX86205.1.
AY898351 Genomic DNA. Translation: AAX86206.1.
AY898359 Genomic DNA. Translation: AAX86214.1.
AY898360 Genomic DNA. Translation: AAX86215.1.
AY898361 Genomic DNA. Translation: AAX86216.1.
AY898362 Genomic DNA. Translation: AAX86217.1.
AY898363 Genomic DNA. Translation: AAX86218.1.
AY898364 Genomic DNA. Translation: AAX86219.1.
AY898365 Genomic DNA. Translation: AAX86220.1.
AY898366 Genomic DNA. Translation: AAX86221.1.
AY898367 Genomic DNA. Translation: AAX86222.1.
AY898368 Genomic DNA. Translation: AAX86223.1.
AY898369 Genomic DNA. Translation: AAX86224.1.
AY898370 Genomic DNA. Translation: AAX86225.1.
AY898371 Genomic DNA. Translation: AAX86226.1.
AY898372 Genomic DNA. Translation: AAX86227.1.
AY898373 Genomic DNA. Translation: AAX86228.1.
AY898374 Genomic DNA. Translation: AAX86229.1.
AY898375 Genomic DNA. Translation: AAX86230.1.
AY898376 Genomic DNA. Translation: AAX86231.1.
AY898377 Genomic DNA. Translation: AAX86232.1.
AY898378 Genomic DNA. Translation: AAX86233.1.
AY898379 Genomic DNA. Translation: AAX86234.1.
AY898380 Genomic DNA. Translation: AAX86235.1.
AY898381 Genomic DNA. Translation: AAX86236.1.
AY898382 Genomic DNA. Translation: AAX86237.1.
AY898383 Genomic DNA. Translation: AAX86238.1.
AY898384 Genomic DNA. Translation: AAX86239.1.
AY898385 Genomic DNA. Translation: AAX86240.1.
AY898386 Genomic DNA. Translation: AAX86241.1.
AY898387 Genomic DNA. Translation: AAX86242.1.
AY898388 Genomic DNA. Translation: AAX86243.1.
AY898389 Genomic DNA. Translation: AAX86244.1.
AY898390 Genomic DNA. Translation: AAX86245.1.
AY898391 Genomic DNA. Translation: AAX86246.1.
AY898392 Genomic DNA. Translation: AAX86247.1.
AY898393 Genomic DNA. Translation: AAX86248.1.
AY898401 Genomic DNA. Translation: AAX86256.1.
AY898402 Genomic DNA. Translation: AAX86257.1.
AY898403 Genomic DNA. Translation: AAX86258.1.
AY898404 Genomic DNA. Translation: AAX86259.1.
AY898405 Genomic DNA. Translation: AAX86260.1.
AY898406 Genomic DNA. Translation: AAX86261.1.
AY898407 Genomic DNA. Translation: AAX86262.1.
AY898408 Genomic DNA. Translation: AAX86263.1.
AY898409 Genomic DNA. Translation: AAX86264.1.
AY898410 Genomic DNA. Translation: AAX86265.1.
AY898411 Genomic DNA. Translation: AAX86266.1.
AY898412 Genomic DNA. Translation: AAX86267.1.
AY898413 Genomic DNA. Translation: AAX86268.1.
AY898414 Genomic DNA. Translation: AAX86269.1.
AY898415 Genomic DNA. Translation: AAX86270.1.
AY898416 Genomic DNA. Translation: AAX86271.1.
AY898417 Genomic DNA. Translation: AAX86272.1.
AY898418 Genomic DNA. Translation: AAX86273.1.
AY898419 Genomic DNA. Translation: AAX86274.1.
AY898420 Genomic DNA. Translation: AAX86275.1.
AY898421 Genomic DNA. Translation: AAX86276.1.
AY898422 Genomic DNA. Translation: AAX86277.1.
AY898423 Genomic DNA. Translation: AAX86278.1.
AY898424 Genomic DNA. Translation: AAX86279.1.
AY898425 Genomic DNA. Translation: AAX86280.1.
AY898426 Genomic DNA. Translation: AAX86281.1.
AY898427 Genomic DNA. Translation: AAX86282.1.
AY898428 Genomic DNA. Translation: AAX86283.1.
AY898429 Genomic DNA. Translation: AAX86284.1.
AY898430 Genomic DNA. Translation: AAX86285.1.
AY898431 Genomic DNA. Translation: AAX86286.1.
AY898432 Genomic DNA. Translation: AAX86287.1.
AY898433 Genomic DNA. Translation: AAX86288.1.
AY898434 Genomic DNA. Translation: AAX86289.1.
AY898435 Genomic DNA. Translation: AAX86290.1.
AY898443 Genomic DNA. Translation: AAX86298.1.
AY898444 Genomic DNA. Translation: AAX86299.1.
AY898445 Genomic DNA. Translation: AAX86300.1.
AY898446 Genomic DNA. Translation: AAX86301.1.
AY898447 Genomic DNA. Translation: AAX86302.1.
AY898448 Genomic DNA. Translation: AAX86303.1.
AY898449 Genomic DNA. Translation: AAX86304.1.
AY898450 Genomic DNA. Translation: AAX86305.1.
AY898451 Genomic DNA. Translation: AAX86306.1.
AY898452 Genomic DNA. Translation: AAX86307.1.
AY898453 Genomic DNA. Translation: AAX86308.1.
AY898454 Genomic DNA. Translation: AAX86309.1.
AY898455 Genomic DNA. Translation: AAX86310.1.
AY898456 Genomic DNA. Translation: AAX86311.1.
AY898457 Genomic DNA. Translation: AAX86312.1.
AY898458 Genomic DNA. Translation: AAX86313.1.
AY898459 Genomic DNA. Translation: AAX86314.1.
AY898460 Genomic DNA. Translation: AAX86315.1.
AY898461 Genomic DNA. Translation: AAX86316.1.
AY898462 Genomic DNA. Translation: AAX86317.1.
AY898463 Genomic DNA. Translation: AAX86318.1.
AY898464 Genomic DNA. Translation: AAX86319.1.
AY898465 Genomic DNA. Translation: AAX86320.1.
AY898466 Genomic DNA. Translation: AAX86321.1.
AY898467 Genomic DNA. Translation: AAX86322.1.
AY898468 Genomic DNA. Translation: AAX86323.1.
AY898469 Genomic DNA. Translation: AAX86324.1.
AY898470 Genomic DNA. Translation: AAX86325.1.
AY898471 Genomic DNA. Translation: AAX86326.1.
AY898472 Genomic DNA. Translation: AAX86327.1.
AY898473 Genomic DNA. Translation: AAX86328.1.
AY898474 Genomic DNA. Translation: AAX86329.1.
AY898475 Genomic DNA. Translation: AAX86330.1.
AY898476 Genomic DNA. Translation: AAX86331.1.
AY898477 Genomic DNA. Translation: AAX86332.1.
AY898485 Genomic DNA. Translation: AAX86340.1.
AY898486 Genomic DNA. Translation: AAX86341.1.
AY898487 Genomic DNA. Translation: AAX86342.1.
AY898488 Genomic DNA. Translation: AAX86343.1.
AY898489 Genomic DNA. Translation: AAX86344.1.
AY898490 Genomic DNA. Translation: AAX86345.1.
AY898491 Genomic DNA. Translation: AAX86346.1.
AY898492 Genomic DNA. Translation: AAX86347.1.
AY898493 Genomic DNA. Translation: AAX86348.1.
AY898494 Genomic DNA. Translation: AAX86349.1.
AY898495 Genomic DNA. Translation: AAX86350.1.
AY898496 Genomic DNA. Translation: AAX86351.1.
AY898497 Genomic DNA. Translation: AAX86352.1.
AY898498 Genomic DNA. Translation: AAX86353.1.
AY898499 Genomic DNA. Translation: AAX86354.1.
AY898500 Genomic DNA. Translation: AAX86355.1.
AY898501 Genomic DNA. Translation: AAX86356.1.
AY898502 Genomic DNA. Translation: AAX86357.1.
AY898503 Genomic DNA. Translation: AAX86358.1.
AY898504 Genomic DNA. Translation: AAX86359.1.
AY898505 Genomic DNA. Translation: AAX86360.1.
AY898506 Genomic DNA. Translation: AAX86361.1.
AY898507 Genomic DNA. Translation: AAX86362.1.
AY898508 Genomic DNA. Translation: AAX86363.1.
AY898509 Genomic DNA. Translation: AAX86364.1.
AY898510 Genomic DNA. Translation: AAX86365.1.
AY898511 Genomic DNA. Translation: AAX86366.1.
AY898512 Genomic DNA. Translation: AAX86367.1.
AY898513 Genomic DNA. Translation: AAX86368.1.
AY898514 Genomic DNA. Translation: AAX86369.1.
AY898515 Genomic DNA. Translation: AAX86370.1.
AY898516 Genomic DNA. Translation: AAX86371.1.
AY898517 Genomic DNA. Translation: AAX86372.1.
AY898518 Genomic DNA. Translation: AAX86373.1.
AY898519 Genomic DNA. Translation: AAX86374.1.
AY898527 Genomic DNA. Translation: AAX86382.1.
AY898528 Genomic DNA. Translation: AAX86383.1.
AY898529 Genomic DNA. Translation: AAX86384.1.
AY898530 Genomic DNA. Translation: AAX86385.1.
AY898531 Genomic DNA. Translation: AAX86386.1.
AY898532 Genomic DNA. Translation: AAX86387.1.
AY898533 Genomic DNA. Translation: AAX86388.1.
AY898534 Genomic DNA. Translation: AAX86389.1.
AY898535 Genomic DNA. Translation: AAX86390.1.
AY898536 Genomic DNA. Translation: AAX86391.1.
AY898537 Genomic DNA. Translation: AAX86392.1.
AY898538 Genomic DNA. Translation: AAX86393.1.
AY898539 Genomic DNA. Translation: AAX86394.1.
AY898540 Genomic DNA. Translation: AAX86395.1.
AY898541 Genomic DNA. Translation: AAX86396.1.
AY898542 Genomic DNA. Translation: AAX86397.1.
AY898543 Genomic DNA. Translation: AAX86398.1.
AY898544 Genomic DNA. Translation: AAX86399.1.
AY898545 Genomic DNA. Translation: AAX86400.1.
AY898546 Genomic DNA. Translation: AAX86401.1.
AY898547 Genomic DNA. Translation: AAX86402.1.
AY898548 Genomic DNA. Translation: AAX86403.1.
AY898549 Genomic DNA. Translation: AAX86404.1.
AY898550 Genomic DNA. Translation: AAX86405.1.
AY898551 Genomic DNA. Translation: AAX86406.1.
AY898552 Genomic DNA. Translation: AAX86407.1.
AY898553 Genomic DNA. Translation: AAX86408.1.
AY898554 Genomic DNA. Translation: AAX86409.1.
AY898555 Genomic DNA. Translation: AAX86410.1.
AY898556 Genomic DNA. Translation: AAX86411.1.
AY898557 Genomic DNA. Translation: AAX86412.1.
AY898558 Genomic DNA. Translation: AAX86413.1.
AY898559 Genomic DNA. Translation: AAX86414.1.
AY898560 Genomic DNA. Translation: AAX86415.1.
AY898561 Genomic DNA. Translation: AAX86416.1.
AY898569 Genomic DNA. Translation: AAX86424.1.
AY898570 Genomic DNA. Translation: AAX86425.1.
AY898571 Genomic DNA. Translation: AAX86426.1.
AY898572 Genomic DNA. Translation: AAX86427.1.
AY898573 Genomic DNA. Translation: AAX86428.1.
AY898574 Genomic DNA. Translation: AAX86429.1.
AY898575 Genomic DNA. Translation: AAX86430.1.
AY898576 Genomic DNA. Translation: AAX86431.1.
AY898577 Genomic DNA. Translation: AAX86432.1.
AY898578 Genomic DNA. Translation: AAX86433.1.
AY898579 Genomic DNA. Translation: AAX86434.1.
AY898580 Genomic DNA. Translation: AAX86435.1.
AY898581 Genomic DNA. Translation: AAX86436.1.
AY898582 Genomic DNA. Translation: AAX86437.1.
AY898583 Genomic DNA. Translation: AAX86438.1.
AY898584 Genomic DNA. Translation: AAX86439.1.
AY898585 Genomic DNA. Translation: AAX86440.1.
AY898586 Genomic DNA. Translation: AAX86441.1.
AY898587 Genomic DNA. Translation: AAX86442.1.
AY898588 Genomic DNA. Translation: AAX86443.1.
AY898589 Genomic DNA. Translation: AAX86444.1.
AY898590 Genomic DNA. Translation: AAX86445.1.
AY898591 Genomic DNA. Translation: AAX86446.1.
AY898592 Genomic DNA. Translation: AAX86447.1.
AY898593 Genomic DNA. Translation: AAX86448.1.
AY898594 Genomic DNA. Translation: AAX86449.1.
AY898595 Genomic DNA. Translation: AAX86450.1.
AY898596 Genomic DNA. Translation: AAX86451.1.
AY898597 Genomic DNA. Translation: AAX86452.1.
AY898598 Genomic DNA. Translation: AAX86453.1.
AY898599 Genomic DNA. Translation: AAX86454.1.
AY898600 Genomic DNA. Translation: AAX86455.1.
AY898601 Genomic DNA. Translation: AAX86456.1.
AY898602 Genomic DNA. Translation: AAX86457.1.
AY898603 Genomic DNA. Translation: AAX86458.1.
AK093127 mRNA. Translation: BAC04066.1. Different initiation.
AK302952 mRNA. Translation: BAG64107.1.
AC068531 Genomic DNA. No translation available.
BC033563 mRNA. Translation: AAH33563.1.
RefSeqiNP_001124390.1. NM_001130918.1.
NP_775894.2. NM_173623.3.
UniGeneiHs.91930.

3D structure databases

ProteinModelPortaliQ8N841.
SMRiQ8N841. Positions 61-393.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129751. 3 interactions.
IntActiQ8N841. 3 interactions.
STRINGi9606.ENSP00000377043.

PTM databases

iPTMnetiQ8N841.
PhosphoSiteiQ8N841.

Polymorphism and mutation databases

BioMutaiTTLL6.
DMDMi172045779.

Proteomic databases

EPDiQ8N841.
PaxDbiQ8N841.
PRIDEiQ8N841.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000393382; ENSP00000377043; ENSG00000170703.
ENST00000433608; ENSP00000399211; ENSG00000170703.
GeneIDi284076.
KEGGihsa:284076.
UCSCiuc002iob.4. human. [Q8N841-1]

Organism-specific databases

CTDi284076.
GeneCardsiTTLL6.
HGNCiHGNC:26664. TTLL6.
HPAiHPA052397.
MIMi610849. gene.
neXtProtiNX_Q8N841.
PharmGKBiPA143485662.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2158. Eukaryota.
ENOG410XNWC. LUCA.
HOVERGENiHBG108618.
InParanoidiQ8N841.
KOiK16582.
OrthoDBiEOG091G01RO.
PhylomeDBiQ8N841.
TreeFamiTF313087.

Miscellaneous databases

GenomeRNAii284076.
PROiQ8N841.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000170703.
ExpressionAtlasiQ8N841. baseline and differential.
GenevisibleiQ8N841. HS.

Family and domain databases

InterProiIPR004344. TTL/TTLL_fam.
IPR027754. TTLL6.
[Graphical view]
PANTHERiPTHR12241:SF96. PTHR12241:SF96. 1 hit.
PfamiPF03133. TTL. 1 hit.
[Graphical view]
PROSITEiPS51221. TTL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTTLL6_HUMAN
AccessioniPrimary (citable) accession number: Q8N841
Secondary accession number(s): B4DZJ5
, C9J233, Q24KB1, Q24KB2, Q24KB6, Q24KF3, Q24KJ5, Q24KN7, Q24KS9, Q24KX1, Q24L13, Q24L55, Q24L76, Q8IYW6, Q8NA62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: September 7, 2016
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.