ID   DNJ5G_HUMAN             Reviewed;         189 AA.
AC   Q8N7S2; Q8IYQ4; Q96RJ8;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-JAN-2012, entry version 70.
DE   RecName: Full=DnaJ homolog subfamily C member 5G;
DE   AltName: Full=Cysteine string protein-gamma;
DE            Short=CSP-gamma;
GN   Name=DNAJC5G;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA   Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA   Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA   Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA   Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA   Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA   Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA   Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA   Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA   Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA   Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA   Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA   Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA   Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA   Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA   Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA   Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA   Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA   Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA   Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 57-165.
RA   Tobaben S., Stahl B.;
RT   "Novel isoforms of the cysteine string protein.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-3, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Embryonic kidney;
RX   PubMed=19413330; DOI=10.1021/ac9004309;
RA   Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA   Mohammed S.;
RT   "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT   a refined SCX-based approach.";
RL   Anal. Chem. 81:4493-4501(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane; Lipid-anchor (By similarity).
CC   -!- TISSUE SPECIFICITY: Testis specific.
CC   -!- PTM: Palmitoylated (By similarity).
CC   -!- SIMILARITY: Contains 1 J domain.
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DR   EMBL; AK097736; BAC05155.1; -; mRNA.
DR   EMBL; BC035194; AAH35194.2; -; mRNA.
DR   EMBL; AF368277; AAK60572.1; -; mRNA.
DR   IPI; IPI00175217; -.
DR   RefSeq; NP_775921.1; NM_173650.1.
DR   UniGene; Hs.116303; -.
DR   ProteinModelPortal; Q8N7S2; -.
DR   SMR; Q8N7S2; 7-120.
DR   DMDM; 50400554; -.
DR   PRIDE; Q8N7S2; -.
DR   Ensembl; ENST00000296097; ENSP00000296097; ENSG00000163793.
DR   Ensembl; ENST00000402462; ENSP00000384305; ENSG00000163793.
DR   GeneID; 285126; -.
DR   KEGG; hsa:285126; -.
DR   UCSC; uc002rjl.1; human.
DR   CTD; 285126; -.
DR   GeneCards; GC02P027498; -.
DR   HGNC; HGNC:24844; DNAJC5G.
DR   HPA; HPA035504; -.
DR   MIM; 613946; gene.
DR   neXtProt; NX_Q8N7S2; -.
DR   GeneTree; ENSGT00600000084291; -.
DR   HOGENOM; HBG713019; -.
DR   HOVERGEN; HBG005414; -.
DR   InParanoid; Q8N7S2; -.
DR   OMA; CTLLTCC; -.
DR   OrthoDB; EOG4HDSVW; -.
DR   PhylomeDB; Q8N7S2; -.
DR   NextBio; 95281; -.
DR   ArrayExpress; Q8N7S2; -.
DR   Bgee; Q8N7S2; -.
DR   CleanEx; HS_DNAJC5G; -.
DR   Genevestigator; Q8N7S2; -.
DR   GermOnline; ENSG00000163793; Homo sapiens.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR001623; DnaJ_N.
DR   InterPro; IPR018253; Heat_shock_DnaJ_CS.
DR   InterPro; IPR003095; Hsp_DnaJ.
DR   Gene3D; G3DSA:1.10.287.110; DnaJ_N; 1.
DR   KO; K09525; -.
DR   Pfam; PF00226; DnaJ; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; DnaJ_N; 1.
DR   PROSITE; PS00636; DNAJ_1; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Complete proteome; Lipoprotein; Membrane; Palmitate;
KW   Phosphoprotein; Polymorphism; Reference proteome.
FT   CHAIN         1    189       DnaJ homolog subfamily C member 5G.
FT                                /FTId=PRO_0000071057.
FT   DOMAIN       17     98       J.
FT   COMPBIAS    131    147       Cys-rich.
FT   MOD_RES       3      3       Phosphothreonine.
FT   VARIANT       4      4       V -> G (in dbSNP:rs17005979).
FT                                /FTId=VAR_033882.
FT   VARIANT      51     51       H -> R (in dbSNP:rs13414011).
FT                                /FTId=VAR_033883.
SQ   SEQUENCE   189 AA;  21433 MW;  EF8FCAE0F1A841A1 CRC64;
     MSTVKEAAHR LSKSEMSLYA VLDLKKGASP EDFKKSYSHS ALLPHPPFEY HLGRKLALRY
     HPDKNPGNAQ AAEIFKEINA AHAILSDSKK RKIYDQHGSL GIYLYDHFGE EGVRYYFILN
     SCWFKTLVIL CTLLTCCCFC CCCCFCCGAL KPPPEQDSGR KYQQNVQSQP PRSGAKCDFR
     SEENSEDDF
//