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Protein
Submitted name:

TRAF3-interacting protein 2

Gene

Traf3ip2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • receptor binding Source: UniProtKB

GO - Biological processi

  • B cell apoptotic process Source: MGI
  • humoral immune response Source: MGI
  • immunoglobulin secretion Source: MGI
  • positive regulation of defense response to virus by host Source: MGI
  • positive regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
  • signal transduction Source: InterPro

Names & Taxonomyi

Protein namesi
Submitted name:
TRAF3-interacting protein 2Imported
Submitted name:
cDNA fis, clone TRACH2006870,moderately similar to Homo sapiens adaptor protein CIKS mRNAImported
Gene namesi
Name:Traf3ip2Imported
ORF Names:mCG_1382Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2143599. Traf3ip2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000019842.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • receptor binding Source: UniProtKB

Protein-protein interaction databases

IntActiQ8N7N6. 8 interactors.
STRINGi10090.ENSMUSP00000019987.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini390 – 531SEFIRInterPro annotationAdd BLAST142

Phylogenomic databases

eggNOGiENOG410IF9W. Eukaryota.
ENOG4111GTJ. LUCA.
GeneTreeiENSGT00390000007714.
HOVERGENiHBG002060.
KOiK21124.
OMAiNYPSPWD.
OrthoDBiEOG091G04TE.
TreeFamiTF329063.

Family and domain databases

Gene3Di3.40.50.10140. 1 hit.
InterProiView protein in InterPro
IPR013568. SEFIR_dom.
IPR000157. TIR_dom.
PfamiView protein in Pfam
PF08357. SEFIR. 1 hit.
PROSITEiView protein in PROSITE
PS51534. SEFIR. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8N7N6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRSIPVEVD ESEPFPSQLL KPIPEYSPEE ELEPPAPNTR NMAPSSLSVL
60 70 80 90 100
QCPPLKLANH QPVSQQVTCL RAKVLEEGEA SFFRRHPELG KDISSCSSGA
110 120 130 140 150
SEPESELGAL PPEHRFTLTE KRNRWLGSQL SAASPDTGHE SDKSDPSLPN
160 170 180 190 200
ALADSFSGGQ EMMPRPRPRP GPHRHRAAPD VPTIDTGYDS QPQDVLGIRQ
210 220 230 240 250
LERPLPLTSS CYLQDLPGPL RSRELPPQFE LERYPMNAQL LPPHPSPQAP
260 270 280 290 300
WNCQYYCPGG PYHHQVPHGH GYPPAAAYQQ VLQPALPGQV LPGARARGPR
310 320 330 340 350
PVQKVILNDS SPQDQEERPA QRDFSFPRLP RDQLYRPPSN GVEAPEESLD
360 370 380 390 400
LPAELRPHGP QAPSLAAVPR PPSNPLARGT LRTSNLPEEL RKVFITYSMD
410 420 430 440 450
TAMEVVKFVN FLLVNGFQTA IDIFEDRIRG IDIIKWMERY LRDKTVMIIV
460 470 480 490 500
AISPKYKQDV EGAESQLDED EHGLHTKYIH RMMQIEFISQ GSMNFRFIPV
510 520 530 540 550
LFPNAKKEHV PTWLQNTHVY SWPKNKKNIL LRLLREEEYV APPRGPLPTL

QVVPL
Length:555
Mass (Da):62,440
Last modified:October 1, 2002 - v1
Checksum:i54B40C8D81C3D827
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160403 Genomic DNA. No translation available.
BC096483 mRNA. Translation: AAH96483.1.
BC138234 mRNA. Translation: AAI38235.1.
BC138235 mRNA. Translation: AAI38236.1.
JX869941 mRNA. Translation: AFY98903.1.
AK098107 mRNA. Translation: BAC05236.1.
AK037407 mRNA. Translation: BAC29801.1.
AK052190 mRNA. Translation: BAC34875.1.
CH466540 Genomic DNA. Translation: EDL04930.1.
RefSeqiNP_598761.2. NM_134000.3.
UniGeneiMm.436686.

Genome annotation databases

EnsembliENSMUST00000019987; ENSMUSP00000019987; ENSMUSG00000019842.
GeneIDi103213.
KEGGimmu:103213.
UCSCiuc007ewa.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8N7N6_MOUSE
AccessioniPrimary (citable) accession number: Q8N7N6
Secondary accession number(s): Q8BH33
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: August 30, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported