Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM216B

Gene

FAM216B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM216B
Gene namesi
Name:FAM216B
Synonyms:C13orf30
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

HGNCiHGNC:26883. FAM216B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA147358510.

Polymorphism and mutation databases

BioMutaiFAM216B.
DMDMi74729231.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 139139Protein FAM216BPRO_0000263728Add
BLAST

Proteomic databases

PaxDbiQ8N7L0.
PRIDEiQ8N7L0.

PTM databases

PhosphoSiteiQ8N7L0.

Expressioni

Gene expression databases

BgeeiQ8N7L0.
CleanExiHS_C13orf30.
GenevisibleiQ8N7L0. HS.

Organism-specific databases

HPAiHPA040118.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000319336.

Structurei

3D structure databases

ProteinModelPortaliQ8N7L0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM216 family.Curated

Phylogenomic databases

eggNOGiENOG410IZ14. Eukaryota.
ENOG4111CP3. LUCA.
GeneTreeiENSGT00390000014571.
HOGENOMiHOG000049059.
HOVERGENiHBG079984.
InParanoidiQ8N7L0.
OMAiVPRIPCI.
OrthoDBiEOG7GTT5X.
PhylomeDBiQ8N7L0.
TreeFamiTF337013.

Family and domain databases

InterProiIPR029373. FAM216.
[Graphical view]
PfamiPF15107. FAM216B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N7L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQNWKRQQK LWNVPQLPFI RVPPSIYDTS LLKALNQGQQ RYFYSIMRIY
60 70 80 90 100
NSRPQWEALQ TRYIHSLQHQ QLLGYITQRE ALSYALVLRD STKRASAKVA
110 120 130
PQRTIPRKTS AMTRRCPSVL PVSVVLPRAQ SKRRQVLRN
Length:139
Mass (Da):16,362
Last modified:October 1, 2002 - v1
Checksum:i1D4FBB5144446FAD
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti134 – 1341R → C.
Corresponds to variant rs35889214 [ dbSNP | Ensembl ].
VAR_033743

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098238 mRNA. Translation: BAC05268.1.
AL138819 Genomic DNA. Translation: CAM17952.1.
CH471075 Genomic DNA. Translation: EAX08682.1.
BC093659 mRNA. Translation: AAH93659.1.
BC112237 mRNA. Translation: AAI12238.1.
CCDSiCCDS9386.1.
RefSeqiNP_001305861.1. NM_001318932.1.
NP_872314.1. NM_182508.2.
UniGeneiHs.16970.

Genome annotation databases

EnsembliENST00000313851; ENSP00000319336; ENSG00000179813.
ENST00000537894; ENSP00000445786; ENSG00000179813.
GeneIDi144809.
KEGGihsa:144809.
UCSCiuc010tfk.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098238 mRNA. Translation: BAC05268.1.
AL138819 Genomic DNA. Translation: CAM17952.1.
CH471075 Genomic DNA. Translation: EAX08682.1.
BC093659 mRNA. Translation: AAH93659.1.
BC112237 mRNA. Translation: AAI12238.1.
CCDSiCCDS9386.1.
RefSeqiNP_001305861.1. NM_001318932.1.
NP_872314.1. NM_182508.2.
UniGeneiHs.16970.

3D structure databases

ProteinModelPortaliQ8N7L0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000319336.

PTM databases

PhosphoSiteiQ8N7L0.

Polymorphism and mutation databases

BioMutaiFAM216B.
DMDMi74729231.

Proteomic databases

PaxDbiQ8N7L0.
PRIDEiQ8N7L0.

Protocols and materials databases

DNASUi144809.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000313851; ENSP00000319336; ENSG00000179813.
ENST00000537894; ENSP00000445786; ENSG00000179813.
GeneIDi144809.
KEGGihsa:144809.
UCSCiuc010tfk.3. human.

Organism-specific databases

CTDi144809.
GeneCardsiFAM216B.
HGNCiHGNC:26883. FAM216B.
HPAiHPA040118.
neXtProtiNX_Q8N7L0.
PharmGKBiPA147358510.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZ14. Eukaryota.
ENOG4111CP3. LUCA.
GeneTreeiENSGT00390000014571.
HOGENOMiHOG000049059.
HOVERGENiHBG079984.
InParanoidiQ8N7L0.
OMAiVPRIPCI.
OrthoDBiEOG7GTT5X.
PhylomeDBiQ8N7L0.
TreeFamiTF337013.

Miscellaneous databases

GenomeRNAii144809.
PROiQ8N7L0.

Gene expression databases

BgeeiQ8N7L0.
CleanExiHS_C13orf30.
GenevisibleiQ8N7L0. HS.

Family and domain databases

InterProiIPR029373. FAM216.
[Graphical view]
PfamiPF15107. FAM216B. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Uterus.
  2. "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart and Lung.

Entry informationi

Entry nameiF216B_HUMAN
AccessioniPrimary (citable) accession number: Q8N7L0
Secondary accession number(s): B1ALI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.