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Q8N7B7

- CT454_HUMAN

UniProt

Q8N7B7 - CT454_HUMAN

Protein

Cancer/testis antigen family 45 member A4/A6

Gene

CT45A4

more
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cancer/testis antigen family 45 member A4/A6
    Alternative name(s):
    Cancer/testis antigen 45-4/6
    Cancer/testis antigen 45A4/45A6
    Gene namesi
    Name:CT45A4
    Synonyms:CT45-4
    AND
    Name:CT45A6
    Synonyms:CT45-6
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:33269. CT45A4.
    HGNC:33271. CT45A6.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164718204.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 189189Cancer/testis antigen family 45 member A4/A6PRO_0000308949Add
    BLAST

    Proteomic databases

    MaxQBiQ8N7B7.
    PaxDbiQ8N7B7.
    PRIDEiQ8N7B7.

    PTM databases

    PhosphoSiteiQ8N7B7.

    Expressioni

    Tissue specificityi

    Testis specific. Expressed in cancer cell lines.1 Publication

    Gene expression databases

    BgeeiQ8N7B7.
    GenevestigatoriQ8N7B7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8N7B7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG125008.
    HOGENOMiHOG000082503.
    HOVERGENiHBG095520.
    InParanoidiQ8N7B7.
    OrthoDBiEOG73V6MH.
    PhylomeDBiQ8N7B7.

    Family and domain databases

    InterProiIPR029307. INT_SG_DDX_CT_C.
    [Graphical view]
    PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8N7B7-1 [UniParc]FASTAAdd to Basket

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    MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS    50
    AMSKAKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS 100
    SFSGDDLECR ETASSPKSQQ EINADIKRKL VKELRCVGQK YEKIFEMLEG 150
    VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI 189
    Length:189
    Mass (Da):21,245
    Last modified:October 1, 2002 - v1
    Checksum:i3C5E639CB3C02146
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY743712 mRNA. Translation: AAW66467.1.
    AY743714 mRNA. Translation: AAW66469.1.
    AK098689 mRNA. Translation: BAC05380.1.
    AL590618 Genomic DNA. Translation: CAI41549.1.
    AL590618 Genomic DNA. Translation: CAI41551.1.
    CCDSiCCDS35405.1.
    RefSeqiNP_001017436.1. NM_001017436.1.
    UniGeneiHs.568346.
    Hs.632281.
    Hs.676560.

    Genome annotation databases

    GeneIDi441520.
    KEGGihsa:441520.
    hsa:541465.
    UCSCiuc004ezb.3. human.

    Polymorphism databases

    DMDMi74751086.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY743712 mRNA. Translation: AAW66467.1 .
    AY743714 mRNA. Translation: AAW66469.1 .
    AK098689 mRNA. Translation: BAC05380.1 .
    AL590618 Genomic DNA. Translation: CAI41549.1 .
    AL590618 Genomic DNA. Translation: CAI41551.1 .
    CCDSi CCDS35405.1.
    RefSeqi NP_001017436.1. NM_001017436.1.
    UniGenei Hs.568346.
    Hs.632281.
    Hs.676560.

    3D structure databases

    ProteinModelPortali Q8N7B7.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8N7B7.

    Polymorphism databases

    DMDMi 74751086.

    Proteomic databases

    MaxQBi Q8N7B7.
    PaxDbi Q8N7B7.
    PRIDEi Q8N7B7.

    Protocols and materials databases

    DNASUi 441520.
    541465.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 441520.
    KEGGi hsa:441520.
    hsa:541465.
    UCSCi uc004ezb.3. human.

    Organism-specific databases

    CTDi 441520.
    541465.
    GeneCardsi GC0XM134926.
    GC0XM134961.
    HGNCi HGNC:33269. CT45A4.
    HGNC:33271. CT45A6.
    MIMi 300795. gene.
    300797. gene.
    neXtProti NX_Q8N7B7.
    PharmGKBi PA164718204.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG125008.
    HOGENOMi HOG000082503.
    HOVERGENi HBG095520.
    InParanoidi Q8N7B7.
    OrthoDBi EOG73V6MH.
    PhylomeDBi Q8N7B7.

    Miscellaneous databases

    NextBioi 110269.
    PROi Q8N7B7.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8N7B7.
    Genevestigatori Q8N7B7.

    Family and domain databases

    InterProi IPR029307. INT_SG_DDX_CT_C.
    [Graphical view ]
    Pfami PF15300. INT_SG_DDX_CT_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, IDENTIFICATION AS A CANCER/TESTIS ANTIGEN.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    3. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCT454_HUMAN
    AccessioniPrimary (citable) accession number: Q8N7B7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

    External Data

    Dasty 3