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Q8N7B7

- CT454_HUMAN

UniProt

Q8N7B7 - CT454_HUMAN

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Protein
Cancer/testis antigen family 45 member A4/A6
Gene
CT45A4, CT45-4
CT45A6, CT45-6
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Organism-specific databases

Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A4/A6
Alternative name(s):
Cancer/testis antigen 45-4/6
Cancer/testis antigen 45A4/45A6
Gene namesi
Name:CT45A4
Synonyms:CT45-4
AND
Name:CT45A6
Synonyms:CT45-6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X
HGNCiHGNC:33269. CT45A4.
HGNC:33271. CT45A6.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164718204.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 189189Cancer/testis antigen family 45 member A4/A6
PRO_0000308949Add
BLAST

Proteomic databases

MaxQBiQ8N7B7.
PaxDbiQ8N7B7.
PRIDEiQ8N7B7.

PTM databases

PhosphoSiteiQ8N7B7.

Expressioni

Tissue specificityi

Testis specific. Expressed in cancer cell lines.1 Publication

Gene expression databases

BgeeiQ8N7B7.
GenevestigatoriQ8N7B7.

Structurei

3D structure databases

ProteinModelPortaliQ8N7B7.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG125008.
HOGENOMiHOG000082503.
HOVERGENiHBG095520.
InParanoidiQ8N7B7.
OrthoDBiEOG73V6MH.
PhylomeDBiQ8N7B7.

Family and domain databases

InterProiIPR029307. INT_SG_DDX_CT_C.
[Graphical view]
PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N7B7-1 [UniParc]FASTAAdd to Basket

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MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS    50
AMSKAKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS 100
SFSGDDLECR ETASSPKSQQ EINADIKRKL VKELRCVGQK YEKIFEMLEG 150
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI 189
Length:189
Mass (Da):21,245
Last modified:October 1, 2002 - v1
Checksum:i3C5E639CB3C02146
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY743712 mRNA. Translation: AAW66467.1.
AY743714 mRNA. Translation: AAW66469.1.
AK098689 mRNA. Translation: BAC05380.1.
AL590618 Genomic DNA. Translation: CAI41549.1.
AL590618 Genomic DNA. Translation: CAI41551.1.
CCDSiCCDS35405.1.
RefSeqiNP_001017436.1. NM_001017436.1.
UniGeneiHs.568346.
Hs.632281.
Hs.676560.

Genome annotation databases

EnsembliENST00000434966; ENSP00000405261; ENSG00000228836.
ENST00000448053; ENSP00000388119; ENSG00000226907.
ENST00000472834; ENSP00000422541; ENSG00000226907.
ENST00000487941; ENSP00000427342; ENSG00000228836.
ENST00000491002; ENSP00000427362; ENSG00000226907.
ENST00000494421; ENSP00000425805; ENSG00000228836.
GeneIDi441520.
KEGGihsa:441520.
hsa:541465.
UCSCiuc004ezb.3. human.

Polymorphism databases

DMDMi74751086.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY743712 mRNA. Translation: AAW66467.1 .
AY743714 mRNA. Translation: AAW66469.1 .
AK098689 mRNA. Translation: BAC05380.1 .
AL590618 Genomic DNA. Translation: CAI41549.1 .
AL590618 Genomic DNA. Translation: CAI41551.1 .
CCDSi CCDS35405.1.
RefSeqi NP_001017436.1. NM_001017436.1.
UniGenei Hs.568346.
Hs.632281.
Hs.676560.

3D structure databases

ProteinModelPortali Q8N7B7.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q8N7B7.

Polymorphism databases

DMDMi 74751086.

Proteomic databases

MaxQBi Q8N7B7.
PaxDbi Q8N7B7.
PRIDEi Q8N7B7.

Protocols and materials databases

DNASUi 441520.
541465.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000434966 ; ENSP00000405261 ; ENSG00000228836 .
ENST00000448053 ; ENSP00000388119 ; ENSG00000226907 .
ENST00000472834 ; ENSP00000422541 ; ENSG00000226907 .
ENST00000487941 ; ENSP00000427342 ; ENSG00000228836 .
ENST00000491002 ; ENSP00000427362 ; ENSG00000226907 .
ENST00000494421 ; ENSP00000425805 ; ENSG00000228836 .
GeneIDi 441520.
KEGGi hsa:441520.
hsa:541465.
UCSCi uc004ezb.3. human.

Organism-specific databases

CTDi 441520.
541465.
GeneCardsi GC0XM134926.
GC0XM134961.
HGNCi HGNC:33269. CT45A4.
HGNC:33271. CT45A6.
MIMi 300795. gene.
300797. gene.
neXtProti NX_Q8N7B7.
PharmGKBi PA164718204.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG125008.
HOGENOMi HOG000082503.
HOVERGENi HBG095520.
InParanoidi Q8N7B7.
OrthoDBi EOG73V6MH.
PhylomeDBi Q8N7B7.

Miscellaneous databases

NextBioi 110269.
PROi Q8N7B7.
SOURCEi Search...

Gene expression databases

Bgeei Q8N7B7.
Genevestigatori Q8N7B7.

Family and domain databases

InterProi IPR029307. INT_SG_DDX_CT_C.
[Graphical view ]
Pfami PF15300. INT_SG_DDX_CT_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, IDENTIFICATION AS A CANCER/TESTIS ANTIGEN.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  3. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCT454_HUMAN
AccessioniPrimary (citable) accession number: Q8N7B7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

Similar proteinsi