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Q8N774

- Q8N774_HUMAN

UniProt

Q8N774 - Q8N774_HUMAN

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Protein
Submitted name: Serine/threonine-protein kinase Nek10
Gene
NEK10
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein tyrosine kinase activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase Nek10Imported
Submitted name:
cDNA FLJ25966 fis, clone TST05207Imported
Gene namesi
Name:NEK10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:18592. NEK10.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38594.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000095163.
KOiK08857.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N774-1 [UniParc]FASTAAdd to Basket

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MELIEGAPLG EHFSSLKEKH HHFTEERLWK IFIQLCLALR YLHKEKRIVH    50
RDLTPNNIML GDKDKVTVTD FGLAKQKQEN SKLTSVVGTI LYSCPEVLKS 100
EPYGEKADVW AVGCILYQMA TLSPPFYSTN MLSLATKIVE AVYEPVPEGI 150
YSEKVTDTIS RCLTPDAEAR PDIVEVSSMI SDVMMKYLDN LSTSQLSLEK 200
KLERERRRTQ RYFMEANRNT VTCHHELAVL SHETFEKASL SSSSSGAASL 250
KSELSESADL PPEGFQASYG KDEDRACDEI LSDDNFNLEN AEKDTYSEVD 300
DELDISDNSS SSSSSPLKES TFNILKRSFS ASGGERQSQT RDFTGGTGSR 350
PRPALLPLDL LLKVPPHMLR AHIKEIEAEL VTGWQSHSLP AVILRNLKDH 400
GSTY 404
Length:404
Mass (Da):45,281
Last modified:October 1, 2002 - v1
Checksum:iCAF5F519F843B88E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093555 Genomic DNA. No translation available.
AC098931 Genomic DNA. No translation available.
AC099535 Genomic DNA. No translation available.
AC133142 Genomic DNA. No translation available.
AK098832 mRNA. Translation: BAC05427.1.
RefSeqiNP_955379.2. NM_199347.2.
UniGeneiHs.506115.
Hs.743887.

Genome annotation databases

EnsembliENST00000357467; ENSP00000350059; ENSG00000163491.
GeneIDi152110.
KEGGihsa:152110.
UCSCiuc003cds.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093555 Genomic DNA. No translation available.
AC098931 Genomic DNA. No translation available.
AC099535 Genomic DNA. No translation available.
AC133142 Genomic DNA. No translation available.
AK098832 mRNA. Translation: BAC05427.1 .
RefSeqi NP_955379.2. NM_199347.2.
UniGenei Hs.506115.
Hs.743887.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000357467 ; ENSP00000350059 ; ENSG00000163491 .
GeneIDi 152110.
KEGGi hsa:152110.
UCSCi uc003cds.1. human.

Organism-specific databases

CTDi 152110.
HGNCi HGNC:18592. NEK10.
PharmGKBi PA38594.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000095163.
KOi K08857.

Miscellaneous databases

ChiTaRSi NEK10. human.
GenomeRNAii 152110.
NextBioi 86891.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  2. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ8N774_HUMAN
AccessioniPrimary (citable) accession number: Q8N774
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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