Q8N774 (Q8N774_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase Nek10 Ensembl ENSP00000350059

Submitted name:
cDNA FLJ25966 fis, clone TST05207 EMBL BAC05427.1

Gene names

Name:

NEK10 Ensembl ENSP00000350059

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAC05427.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein tyrosine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8N774 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: CAF5F519F843B88E	FASTA	404	45,281
	10 20 30 40 50 60 MELIEGAPLG EHFSSLKEKH HHFTEERLWK IFIQLCLALR YLHKEKRIVH RDLTPNNIML 70 80 90 100 110 120 GDKDKVTVTD FGLAKQKQEN SKLTSVVGTI LYSCPEVLKS EPYGEKADVW AVGCILYQMA 130 140 150 160 170 180 TLSPPFYSTN MLSLATKIVE AVYEPVPEGI YSEKVTDTIS RCLTPDAEAR PDIVEVSSMI 190 200 210 220 230 240 SDVMMKYLDN LSTSQLSLEK KLERERRRTQ RYFMEANRNT VTCHHELAVL SHETFEKASL 250 260 270 280 290 300 SSSSSGAASL KSELSESADL PPEGFQASYG KDEDRACDEI LSDDNFNLEN AEKDTYSEVD 310 320 330 340 350 360 DELDISDNSS SSSSSPLKES TFNILKRSFS ASGGERQSQT RDFTGGTGSR PRPALLPLDL 370 380 390 400 LLKVPPHMLR AHIKEIEAEL VTGWQSHSLP AVILRNLKDH GSTY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"NEDO human cDNA sequencing project." Oshima A., Takahashi-Fujii A., Tanase T., Imose N., Takeuchi K., Arita M., Musashino K., Yuuki H., Hara H., Suzuki Y., Hata H., Nakagawa K., Mizuno S., Morinaga M., Kawamura M., Sugiyama T., Irie R., Otsuki T. , Sato H., Nishikawa T., Sugiyama A., Kawakami B., Nagai K., Isogai T., Sugano S. Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL BAC05427.1.
[2]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC093555 Genomic DNA. No translation available. AC098931 Genomic DNA. No translation available. AC099535 Genomic DNA. No translation available. AC133142 Genomic DNA. No translation available. AK098832 mRNA. Translation: BAC05427.1.
IPI	IPI00941775.
RefSeq	NP_955379.2. NM_199347.2.
UniGene	Hs.506115. Hs.741638.
3D structure databases
SMR	Q8N774. Positions 10-213.
ModBase	Search...
Proteomic databases
PRIDE	Q8N774.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000357467; ENSP00000350059; ENSG00000163491.
GeneID	152110.
KEGG	hsa:152110.
UCSC	uc003cds.1. human.
Organism-specific databases
CTD	152110.
HGNC	HGNC:18592. NEK10.
PharmGKB	PA38594.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000095163.
KO	K08857.
Gene expression databases
ArrayExpress	Q8N774.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR008266. Tyr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NEK10. human.
GenomeRNAi	152110.
NextBio	86891.

Entry information

Entry name

Q8N774_HUMAN

Accession

Primary (citable) accession number: Q8N774

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.