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Q8N6I9

- Q8N6I9_HUMAN

UniProt

Q8N6I9 - Q8N6I9_HUMAN

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Protein
Submitted name:

GNAO1 protein

Gene

GNAO1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-KW
  3. signal transducer activity Source: UniProtKB-KW

GO - Biological processi

  1. adenylate cyclase-modulating G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransducerSAAS annotation

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
GNAO1 proteinImported
Gene namesi
Name:GNAO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28771.

PTM / Processingi

Proteomic databases

PRIDEiQ8N6I9.

Expressioni

Gene expression databases

BgeeiQ8N6I9.
ExpressionAtlasiQ8N6I9. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ8N6I9.
SMRiQ8N6I9. Positions 1-293.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG063184.
KOiK04534.

Family and domain databases

Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
PR00441. GPROTEINAI.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8N6I9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIIHEDGFS GEDVKQYKPV VYSNTIQSLA AIVRAMDTLG IEYGDKERKA
60 70 80 90 100
DAKMVCDVVS RMEDTEPFSA ELLSAMMRLW GDSGIQECFN RSREYQLNDS
110 120 130 140 150
AKYYLDSLDR IGAADYQPTE QDILRTRVKT TGIVETHFTF KNLHFRLFDV
160 170 180 190 200
GGQRSERKKW IHCFEDVTAI IFCVALSGYD QVLHEDETTN RMHESLMLFD
210 220 230 240 250
SICNNKFFID TSIILFLNKK DLFGEKIKKS PLTICFPEYT GPNTYEDAAA
260 270 280 290 300
YIQAQFESKN RSPNKEIYCH MTCATDTNNI QVVFDAVTDI IIANNLRGCG

LY
Length:302
Mass (Da):34,609
Last modified:March 1, 2004 - v2
Checksum:iB6902F0B0AA8DE09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC030027 mRNA. Translation: AAH30027.2.
RefSeqiNP_066268.1. NM_020988.2.
NP_620073.2. NM_138736.2.
UniGeneiHs.644524.

Genome annotation databases

GeneIDi2775.
KEGGihsa:2775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC030027 mRNA. Translation: AAH30027.2 .
RefSeqi NP_066268.1. NM_020988.2.
NP_620073.2. NM_138736.2.
UniGenei Hs.644524.

3D structure databases

ProteinModelPortali Q8N6I9.
SMRi Q8N6I9. Positions 1-293.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q8N6I9.

Proteomic databases

PRIDEi Q8N6I9.

Protocols and materials databases

DNASUi 2775.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2775.
KEGGi hsa:2775.

Organism-specific databases

CTDi 2775.
PharmGKBi PA28771.

Phylogenomic databases

HOVERGENi HBG063184.
KOi K04534.

Miscellaneous databases

ChiTaRSi GNAO1. human.
GenomeRNAii 2775.
NextBioi 10916.

Gene expression databases

Bgeei Q8N6I9.
ExpressionAtlasi Q8N6I9. baseline and differential.

Family and domain databases

Gene3Di 1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR10218. PTHR10218. 1 hit.
Pfami PF00503. G-alpha. 1 hit.
[Graphical view ]
PRINTSi PR00318. GPROTEINA.
PR00441. GPROTEINAI.
SMARTi SM00275. G_alpha. 1 hit.
[Graphical view ]
SUPFAMi SSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiQ8N6I9_HUMAN
AccessioniPrimary (citable) accession number: Q8N6I9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: March 1, 2004
Last modified: October 29, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.