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Q8N6I9

- Q8N6I9_HUMAN

UniProt

Q8N6I9 - Q8N6I9_HUMAN

Protein
Submitted name:

GNAO1 protein

Gene

GNAO1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 2 (01 Mar 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-KW
    3. signal transducer activity Source: UniProtKB-KW

    GO - Biological processi

    1. adenylate cyclase-modulating G-protein coupled receptor signaling pathway Source: InterPro

    Keywords - Molecular functioni

    TransducerSAAS annotation

    Keywords - Ligandi

    GTP-bindingSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GNAO1 proteinImported
    Gene namesi
    Name:GNAO1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA28771.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8N6I9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8N6I9.
    BgeeiQ8N6I9.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ8N6I9.
    SMRiQ8N6I9. Positions 1-293.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG063184.
    KOiK04534.

    Family and domain databases

    Gene3Di1.10.400.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR001408. Gprotein_alpha_I.
    IPR001019. Gprotein_alpha_su.
    IPR011025. GproteinA_insert.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR10218. PTHR10218. 1 hit.
    PfamiPF00503. G-alpha. 1 hit.
    [Graphical view]
    PRINTSiPR00318. GPROTEINA.
    PR00441. GPROTEINAI.
    SMARTiSM00275. G_alpha. 1 hit.
    [Graphical view]
    SUPFAMiSSF47895. SSF47895. 1 hit.
    SSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8N6I9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIIHEDGFS GEDVKQYKPV VYSNTIQSLA AIVRAMDTLG IEYGDKERKA    50
    DAKMVCDVVS RMEDTEPFSA ELLSAMMRLW GDSGIQECFN RSREYQLNDS 100
    AKYYLDSLDR IGAADYQPTE QDILRTRVKT TGIVETHFTF KNLHFRLFDV 150
    GGQRSERKKW IHCFEDVTAI IFCVALSGYD QVLHEDETTN RMHESLMLFD 200
    SICNNKFFID TSIILFLNKK DLFGEKIKKS PLTICFPEYT GPNTYEDAAA 250
    YIQAQFESKN RSPNKEIYCH MTCATDTNNI QVVFDAVTDI IIANNLRGCG 300
    LY 302
    Length:302
    Mass (Da):34,609
    Last modified:March 1, 2004 - v2
    Checksum:iB6902F0B0AA8DE09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC030027 mRNA. Translation: AAH30027.2.
    RefSeqiNP_066268.1. NM_020988.2.
    NP_620073.2. NM_138736.2.
    UniGeneiHs.644524.

    Genome annotation databases

    GeneIDi2775.
    KEGGihsa:2775.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC030027 mRNA. Translation: AAH30027.2 .
    RefSeqi NP_066268.1. NM_020988.2.
    NP_620073.2. NM_138736.2.
    UniGenei Hs.644524.

    3D structure databases

    ProteinModelPortali Q8N6I9.
    SMRi Q8N6I9. Positions 1-293.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q8N6I9.

    Proteomic databases

    PRIDEi Q8N6I9.

    Protocols and materials databases

    DNASUi 2775.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2775.
    KEGGi hsa:2775.

    Organism-specific databases

    CTDi 2775.
    PharmGKBi PA28771.

    Phylogenomic databases

    HOVERGENi HBG063184.
    KOi K04534.

    Miscellaneous databases

    ChiTaRSi GNAO1. human.
    GenomeRNAii 2775.
    NextBioi 10916.

    Gene expression databases

    ArrayExpressi Q8N6I9.
    Bgeei Q8N6I9.

    Family and domain databases

    Gene3Di 1.10.400.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR001408. Gprotein_alpha_I.
    IPR001019. Gprotein_alpha_su.
    IPR011025. GproteinA_insert.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR10218. PTHR10218. 1 hit.
    Pfami PF00503. G-alpha. 1 hit.
    [Graphical view ]
    PRINTSi PR00318. GPROTEINA.
    PR00441. GPROTEINAI.
    SMARTi SM00275. G_alpha. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47895. SSF47895. 1 hit.
    SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ8N6I9_HUMAN
    AccessioniPrimary (citable) accession number: Q8N6I9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: March 1, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.