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Q8N6B5

- Q8N6B5_HUMAN

UniProt

Q8N6B5 - Q8N6B5_HUMAN

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Protein
Submitted name:

Forkhead box P2, isoform CRA_d

Gene

FOXP2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box P2, isoform CRA_dImported
Submitted name:
Forkhead box protein P2Imported
Submitted name:
Forkhead/winged helix transcription factorImported
Gene namesi
Name:FOXP2Imported
ORF Names:hCG_1813384Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:13875. FOXP2.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28242.

Expressioni

Gene expression databases

ExpressionAtlasiQ8N6B5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ8N6B5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00750000117475.
HOGENOMiHOG000092089.
KOiK09409.

Family and domain databases

InterProiIPR015880. Znf_C2H2-like.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8N6B5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQESATETIS NSSMNQNGMS TLSSQLDAGS RDGRSSGDTS SEVSTVELLH
60 70 80 90 100
LQQQQALQAA RQLLLQQQTS GLKSPKSSDK QRPLQELLPE TKLCICGHSS
110 120 130 140 150
GDGHPHNTFA VPVSVAMMTP QVITPQQMQQ ILQQQVLSPQ QLQALLQQQQ
160 170 180 190 200
AVMLQQQQLQ EFYKKQQEQL HLQLLQQQQQ QQQQQQQQQQ QQQQQQQQQQ
210 220 230 240 250
QQQQQQQQQQ QQQQQHPGKQ AKEQQQQQQQ QQQLAAQQLV FQQQLLQMQQ
260 270 280 290 300
LQQQQHLLSL QRQGLISIPP GQAALPVQSL PQAGLSPAEI QQLWKEVTGV
310 320 330 340 350
HSMEDNGIKH GGLDLTTNNS SSTTSSNTSK ASPPITHHSI VNGQSSVLSA
360 370 380 390 400
RRDSSSHEET GASHTLYGHG VCKWPGCESI CEDFGQFLKH LNNEHALDDR
410 420 430 440 450
STAQCRVQMQ VVQQLEIQLS KERERLQAMM THLHMRPSEP KPSPKPVSAY

CFINSK
Length:456
Mass (Da):51,279
Last modified:October 1, 2002 - v1
Checksum:iDC1F01FD84D75211
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei456 – 4561Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
KF458557 Genomic DNA. No translation available.
KF458560 Genomic DNA. No translation available.
KF458565 Genomic DNA. No translation available.
AF467259 mRNA. Translation: AAM60769.1.
CH471070 Genomic DNA. Translation: EAW83482.1.
RefSeqiNP_001166238.1. NM_001172767.2.
UniGeneiHs.282787.

Genome annotation databases

EnsembliENST00000390668; ENSP00000375084; ENSG00000128573.
GeneIDi93986.
KEGGihsa:93986.
UCSCiuc003vhc.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
KF458557 Genomic DNA. No translation available.
KF458560 Genomic DNA. No translation available.
KF458565 Genomic DNA. No translation available.
AF467259 mRNA. Translation: AAM60769.1 .
CH471070 Genomic DNA. Translation: EAW83482.1 .
RefSeqi NP_001166238.1. NM_001172767.2.
UniGenei Hs.282787.

3D structure databases

ProteinModelPortali Q8N6B5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000390668 ; ENSP00000375084 ; ENSG00000128573 .
GeneIDi 93986.
KEGGi hsa:93986.
UCSCi uc003vhc.3. human.

Organism-specific databases

CTDi 93986.
HGNCi HGNC:13875. FOXP2.
PharmGKBi PA28242.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00750000117475.
HOGENOMi HOG000092089.
KOi K09409.

Miscellaneous databases

ChiTaRSi FOXP2. human.
GenomeRNAii 93986.
NextBioi 78260.

Gene expression databases

ExpressionAtlasi Q8N6B5. baseline and differential.

Family and domain databases

InterProi IPR015880. Znf_C2H2-like.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "FOXP2: novel exons, splice variants, and CAG repeat length stability."
    Bruce H.A., Margolis R.L.
    Hum. Genet. 111:136-144(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AmygdalaImported.
  3. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ8N6B5_HUMAN
AccessioniPrimary (citable) accession number: Q8N6B5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3